“…Pancreatic cancer is without any doubt the malignancy with the poorest prognosis and the lowest survival rate. …”
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“…This paper reviewed the natural history of pancreatic cancer, the current clinical practice and the future in pancreatic cancer management.…”
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“…AIM OF DATABASE: The Danish Pancreatic Cancer Database aims to prospectively register the epidemiology, diagnostic workup, diagnosis, treatment, and outcome of patients with pancreatic cancer in Denmark at an institutional and national level. …”
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“…Abnormal expression in sugar moieties can impact the function of various glycoproteins, including mucins, surface receptors, adhesive proteins, proteoglycans, as well as their effectors and binding ligands, resulting in an increase in pancreatic cancer invasiveness and a cancer-favored microenvironment. …”
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“…Chemotherapy and radiotherapy can be both used in cases of non-resectable pancreatic cancer. In cases of pancreatic neoplasm that is locally advanced, non-resectable, but non-metastatic, it is possible to apply percutaneous treatments that are able to induce tumor cytoreduction. …”
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“…Pancreatic cancer remains a fatal disease in the majority of patients. …”
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“…Pancreatic cancer (PC) is one of the most common causes of cancer-related death. …”
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“…Treatment of pancreatic cancer is multimodal and surgery is an essential part, mandatory for curative potential. …”
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“…The incidence of pancreatic cancer is increasing as the population ages but treatment advancements continue to lag far behind. …”
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“…Pancreatic ductal adenocarcinoma (PDAC), commonly referred to as pancreatic cancer, ranks among the leading causes of cancer-related deaths in the Western world due to disease presentation at an advanced stage, early metastasis and generally a very limited response to chemotherapy or radiotherapy. …”
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“…Pancreatic cancer has been classified as a cancer of unmet need. …”
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“…Pancreatic cancer is one of the worst, as almost 100% of patients will die within 5 years after diagnosis. …”
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“…Pancreatic cancer is the third leading cause of cancer related death and by 2030, it will be second only to lung cancer. …”
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“…Pancreatic cancer is one of the most lethal malignancies. …”
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“…Pancreatic cancer is a growing source of cancer related death, yet has poor survival rates which have not improved in the last few decades. …”
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“…Pancreatic cancer is the fourth leading cause of cancer-related death in the United States, with increasing incidence. …”
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“…The diagnosis of pancreatic cancer relies on imaging and tissue biopsy, and the only curative therapy is complete surgical resection. …”
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“…Pancreatic cancer is the fourth most common cause of cancer-related deaths in both men and women. …”
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“…In this article, we aim to review current and future biomarkers that has potential serve as critical tools for early diagnostic, predictive and prognostic indications in pancreatic cancer.…”
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