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781por Sun, Zhong, Xiong, ChengLong, Teh, Seoh Wei, Lim, Jonathan Chee Woei, Kumar, Suresh, Thilakavathy, Karuppiah“…Pancreatic cancer is a highly lethal disease, and most patients remain asymptomatic until the disease enters advanced stages. …”
Publicado 2019
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782
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783“…Metastasis is the main cause of high pancreatic cancer (PaCa) mortality and trials dampening PaCa mortality rates are not satisfying. …”
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785por Damanakis, Alexander I., Ostertag, Luisa, Waldschmidt, Dirk, Kütting, Fabian, Quaas, Alexander, Plum, Patrick, Bruns, Christiane J., Gebauer, Florian, Popp, FelixEnlace del recurso
Publicado 2019
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786por Fukushima, Daizo, Nishino, Noriyuki, Hamada, Koichi, Horikawa, Yoshinori, Shiwa, Yoshiki, Nishida, Shinya, Koyanagi, Ryota, Abe, Tsuyoshi, Suzuki, Nobuyasu, Takano, Yoshinao, Teranishi, Yasushi, Munechika, Hirotsugu, Miura, Yoshihiro, Nakasato, Tatsuhiko, Sakuma, Hideo“…OBJECTIVES: The aim of this study was to assess the characteristic radiological features of early-stage pancreatic cancer (PC). METHODS: Between 2009 and 2016, 510 PC patients were selected from our hospital cancer registry database based on International Classification of Diseases for Oncology-3 (C25). …”
Publicado 2020
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787“…Herein, we summarize the current evidence of different treatment strategies for pancreatic cancer with a focus on conversion surgery and the impact of neoadjuvant treatment in this setting.…”
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788por Azizian, Azadeh, Rühlmann, Felix, Krause, Tanja, Bernhardt, Markus, Jo, Peter, König, Alexander, Kleiß, Mathias, Leha, Andreas, Ghadimi, Michael, Gaedcke, Jochen“…We analyzed data of 93 patients with pancreatic cancer in the training set and 41 in the validation set, both retrospectively. …”
Publicado 2020
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789por Mahajan, Ujjwal M, Goni, Elisabetta, Langhoff, Enno, Li, Qi, Costello, Eithne, Greenhalf, William, Kruger, Stephan, Ormanns, Steffen, Halloran, Christopher, Ganeh, Paula, Marron, Manuela, Lämmerhirt, Felix, Zhao, Yue, Beyer, Georg, Weiss, Frank-Ulrich, Sendler, Matthias, Bruns, Christiane J, Kohlmann, Thomas, Kirchner, Thomas, Werner, Jens, D’Haese, Jan G, von Bergwelt-Baildon, Michael, Heinemann, Volker, Neoptolemos, John P, Büchler, Markus W, Belka, Claus, Boeck, Stefan, Lerch, Markus M, Mayerle, Julia“…METHODS: CatD expression quantified by immunohistochemistry of tumor-tissue microarrays of 403 resected pancreatic cancer patients from the ESPAC-Tplus trial, a translational study within the ESPAC (European Study Group for Pancreatic Cancer) trials, was dichotomously distributed to low and high H scores (cut off 22.35) for survival and multivariable analysis. …”
Publicado 2019
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790por Liu, Chen, Deng, Shengming, Jin, Kaizhou, Gong, Yitao, Cheng, He, Fan, Zhiyao, Qian, Yunzhen, Huang, Qiuyi, Ni, Quanxing, Luo, Guopei, Yu, Xianjun“…However, the characteristics of Lewis-negative pancreatic cancer are unidentified. Clinicopathological characteristics of 853 patients with pancreatic cancer were examined. …”
Publicado 2020
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791“…Novel therapeutics must be equipped to deal with this challenge. microRNAs (miRNAs) have emerged as strong candidates to fill this role due to their multitargeted function. miRNAs have been shown to have important roles in pancreatic cancer resistance. In this review, we summarize the recent advancement in miRNA research related to PDAC therapeutic resistance mechanisms and the potential of miRNAs as therapeutic agents for future clinical management of PDAC.…”
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792por Filippini, D. M., Grassi, E., Palloni, A., Carloni, R., Casadei, R., Ricci, C., Serra, C., Ercolani, G., Brandi, G., Di Marco, M.“…BACKGROUND: Metastatic pancreatic cancer has a median overall survival of less than 12 months, even if treated with chemotherapy. …”
Publicado 2020
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793por Su, Dan, Guo, Xiaofeng, Huang, Leyi, Ye, Huilin, Li, Zhiguo, Lin, Longfa, Chen, Rufu, Zhou, Quanbo“…In the present study, we aimed to determine whether interplay between pancreatic cancer cells and SCs via paracrine signaling contributes to cancer progression. …”
Publicado 2020
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794
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795por Wu, Bechien U., Butler, Rebecca K., Lustigova, Eva, Lawrence, Jean M., Chen, Wansu“…IMPORTANCE: New-onset diabetes after the age of 50 years is a potential indicator of pancreatic cancer. Understanding the associations between hyperglycemia, diabetes, and pancreatic cancer, including pancreatic ductal adenocarcinoma, is key to developing an approach to early detection. …”
Publicado 2020
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796
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797por Poulia, Kalliopi Anna, Sarantis, Panagiotis, Antoniadou, Dimitra, Koustas, Evangelos, Papadimitropoulou, Adriana, Papavassiliou, Athanasios G., Karamouzis, Michalis V.“…Cachexia is a major characteristic of multiple non-malignant diseases, advanced and metastatic cancers and it is highly prevalent in pancreatic cancer, affecting almost 70%–80% of the patients. …”
Publicado 2020
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798“…PURPOSE: Pancreatic cancer (PC) has poor prognosis despite systemic treatment. …”
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799“…Pancreatic cancer is a lethal disease in a large part due to the systemic nature at the time of diagnosis. …”
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800“…Pancreatic cancer (PC) is a highly lethal tumor with controversial high glucose uptake and hypomicrovascularity, and the hypomicrovasculature, which is considered to have poor perfusion, blocks the delivery of drugs to tumors. …”
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