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961por Korc, Murray“…Beneficial responses were attributed to heparin-induced vascular normalization, ensuing CD8(+) T-cell infiltration, and M1 macrophage polarization, suggesting the potential for heparin-anchored therapies in cold tumors such as pancreatic cancer. See related article by Wei et al., p. 2525…”
Publicado 2023
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962por Rosenzweig, Allison, Berlin, Jordan, Chari, Suresh, Kindler, Hedy, Matrisian, Lynn, Mayoral, Allison, Mills, Jeannine, Nissen, Nicholas, Picozzi, Vincent, Zelada-Arenas, Fatima, Fleming, Jason“…Pancreatic cancer is one of the few cancer types in the US with incidence and death rates continuing to rise. …”
Publicado 2023
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963“…SIMPLE SUMMARY: Altered metabolism is one of the main driving forces of pancreatic cancer development, progression, and response to treatment. …”
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964por Willems, R. A. L., Michiels, N., Lanting, V. R., Bouwense, S., van den Broek, B. L. J., Graus, M., Klok, F. A., Groot Koerkamp, B., de Laat, B., Roest, M., Wilmink, J. W., van Es, N., Mieog, J. S. D., ten Cate, H., de Vos-Geelen, J.“…It is known that patients with pancreatic cancer have a high risk of developing thrombosis. …”
Publicado 2023
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965por Takada, Ryoji, Ikezawa, Kenji, Yamai, Takuo, Watsuji, Ko, Seiki, Yusuke, Kawamoto, Yasuharu, Hirao, Takeru, Higashi, Sena, Urabe, Makiko, Kai, Yugo, Nakabori, Tasuku, Uehara, Hiroyuki, Kotani, Michiyo, Yagi, Toshinari, Kimura, Miho, Nozaki, Keisuke, Takagi, Mari, Ohkawa, Kazuyoshi“…BACKGROUND: Nanoliposomal irinotecan (nal-IRI) plus 5-fluorouracil (5-FU)/levo-leucovorin (Levo-LV) was approved for unresectable pancreatic cancer (UR-PC) in March 2020 in Japan. Levo-LV is administered by intravenous infusion over 120 min following 90 min intravenous infusion of nal-IRI (conventional method), causing a significant burden on both patients and the outpatient chemotherapy room owing to the prolonged administration time. …”
Publicado 2023
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966por Wei, Ling, Sun, Jujie, Wang, Xingwu, Huang, Yizhou, Huang, Linying, Han, Linyu, Zheng, Yanxiu, Xu, Yuan, Zhang, Nasha, Yang, Ming“…Pancreatic cancer is the eighth leading cause of cancer-related deaths worldwide. …”
Publicado 2023
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967“…SIMPLE SUMMARY: Pancreatic cancer is a deadly disease with limited effective treatments. …”
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968“…Pancreatic cancer is a highly aggressive form of cancer with a five-year survival rate of only ten percent. …”
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970por Hernandez, Diego, Wagner, Fabienne, Hernandez-Villafuerte, Karla, Schlander, Michael“…PURPOSE: Pancreatic cancer is characterized by its high mortality, usually attributed to its diagnosis in already advanced stages. …”
Publicado 2022
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971“…He was ultimately diagnosed with pancreatic cancer using computed tomography. DISCUSSION: Leser-Trélat sign is a rare cutaneous marker for underlying malignancy. …”
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972por Storz, Peter“…During development of pancreatic cancer macrophage-mediated inflammatory processes and the formation of cancerous lesions are tightly connected. …”
Publicado 2023
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973por Levink, Iris J. M., Jansen, Maurice P. H. M., Azmani, Zakia, van IJcken, Wilfred, van Marion, Ronald, Peppelenbosch, Maikel P., Cahen, Djuna L., Fuhler, Gwenny M., Bruno, Marco J.“…Molecular profiling may enable earlier detection of pancreatic cancer (PC) in high-risk individuals undergoing surveillance and allow for personalization of treatment. …”
Publicado 2023
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974“…Pancreatic cancer commonly metastasizes to the liver, lung or adrenal glands, but rarely spreads to the colon. …”
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977“…Pancreatic cancer (PC) is one of the most common malignancies. …”
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978por Cammarota, Anna Lisa, Falco, Antonia, Basile, Anna, Molino, Carlo, Chetta, Massimiliano, D’Angelo, Gianni, Marzullo, Liberato, De Marco, Margot, Turco, Maria Caterina, Rosati, Alessandra“…At the molecular level, heterogeneous oncogenic and loss-of-function mutations in tumor suppressors, in which KRAS variants are the most frequent, characterize pancreatic cancer cells. Furthermore, altered ductal cells constitute only a modest portion of pancreatic cancer tumor mass, with the remainder made up of stromal cells and components. …”
Publicado 2023
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979por Miyashita, Yudai, Ose, Naoko, Okami, Jiro, Takami, Koji, Sakamaki, Yasushi, Ikeda, Naoki, Hayakawa, Masanobu, Higashiyama, Masahiko, Kodama, Ken, Susaki, Yoshiyuki, Funakoshi, Yasunobu, Maeda, Jun, Shintani, Yasushi“…PURPOSE: As the number of long-term survivors of pancreatic cancer is expected to increase thanks to recent advances in multidisciplinary treatment and earlier diagnoses of pancreatic cancer, we are likely to encounter more cases of postoperative pulmonary nodules. …”
Publicado 2023
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980