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982por Awais, Nimra, Satnarine, Travis, Ahmed, Areeg, Haq, Ayesha, Patel, Deepkumar, Hernandez, Grethel N, Seffah, Kofi D, Zaman, Mustafa Abrar, Khan, Safeera“…Pancreatic cancer is a malignant tumor with one of the worst prognosis. …”
Publicado 2023
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983“…OBJECTIVE: The efficacy of platinum-based chemotherapy (PtCh) for pancreatic cancer (PC) patients with DNA damage repair gene mutations (DDRm) compared to those without DDRm remains uncertain. …”
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984por Wang, Jing, Koch, Dominik T., Hofmann, Felix O., Härtwig, Daniel, Beirith, Iris, Janssen, Klaus Peter, Bazhin, Alexandr V., Niess, Hanno, Werner, Jens, Renz, Bernhard W., Ilmer, Matthias“…These findings shed new insights into regulatory mechanisms for the canonical WNT pathway in pancreatic cancer cells. It may also have potential value for treatment stratification of PDAC.…”
Publicado 2023
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985“…Pancreatic cancer (PDAC) is one of the most aggressive solid tumors and is showing increasing incidence. …”
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986por Zervos, Emmanuel E, Osborne, Dana, Boe, Brian A, Luzardo, German, Goldin, Steven B, Rosemurgy, Alexander S“…BACKGROUND: The purpose of this study was to determine risk factors for development of malignant ascites and its prognostic significance in patients with pancreatic cancer. METHODS: A prospective database was queried to identify patients with pancreatic cancer who develop ascites. …”
Publicado 2006
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987por Oikawa, T., Kushuhara, M., Ishikawa, S., Hitomi, J., Kono, A., Iwanaga, T., Yamaguchi, K.“…ET-1 was detected in 11 of 12 pancreatic cancer cell lines (92%) while ET-2 and ET-3 were detectable in only one cell line. …”
Publicado 1994
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988
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989por Carmichael, J., Fink, U., Russell, R. C., Spittle, M. F., Harris, A. L., Spiessi, G., Blatter, J.“…For these reasons and because of its novel mode of action, gemcitabine warrants further investigation in combination studies in pancreatic cancer. IMAGES:…”
Publicado 1996
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990por Li, Junsheng, Kleeff, Jörg, Guo, Junchao, Fischer, Lars, Giese, Nathalia, Büchler, Markus W, Friess, Helmut“…BACKGROUND: Pancreatic cancer is an aggressive malignancy characterized by low responsiveness to chemotherapy and radiotherapy. …”
Publicado 2003
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991por Kaufman, Howard L, Kim-Schulze, Seunghee, Manson, Kelledy, DeRaffele, Gail, Mitcham, Josephine, Seo, Kang Seok, Kim, Dae Won, Marshall, John“…PATIENTS AND METHODS: Ten patients with advanced pancreatic cancer were treated on a Phase I clinical trial. …”
Publicado 2007
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992por Kayed, Hany, Bekasi, Sandor, Keleg, Shereen, Michalski, Christoph W, Giese, Thomas, Friess, Helmut, Kleeff, Jörg“…CONCLUSION: BGLAP is expressed in pancreatic cancer cells, where it potentially increases pancreatic cancer cell growth and invasion through autocrine and/or paracrine mechanisms.…”
Publicado 2007
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993“…The possible association of specific fatty acid (FA) intake and pancreatic cancer risk was investigated in a population-based case–control study of 462 histologically confirmed cases and 4721 frequency-matched controls in eight Canadian provinces between 1994 and 1997. …”
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994por Stocken, D D, Büchler, M W, Dervenis, C, Bassi, C, Jeekel, H, Klinkenbijl, J H G, Bakkevold, K E, Takada, T, Amano, H, Neoptolemos, J P“…These results show that chemotherapy is effective adjuvant treatment in pancreatic cancer but not chemoradiation. Further studies with chemoradiation are warranted in patients with positive resection margins, as chemotherapy appeared relatively ineffective in this patient subgroup.…”
Publicado 2005
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995por Evans, J D, Stark, A, Johnson, C D, Daniel, F, Carmichael, J, Buckels, J, Imrie, C W, Brown, P, Neoptolemos, J P“…Pancreatic cancer has a poor response to conventional chemotherapy and radiotherapy. …”
Publicado 2001
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996por Stevenson, A J, Giles, M S, Hall, K T, Goodwin, D J, Calderwood, M A, Markham, A F, Whitehouse, A“…These data suggest that herpesvirus saimiri may have potential as an oncolytic agent for the treatment of pancreatic cancer. © 2000 Cancer Research Campaign…”
Publicado 2000
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997“…Thus, the ability of hK7 to degrade desmogleins was assessed and the effect of hK7 expression on desmoglein 2 was examined in cultured pancreatic cancer cells. METHODS: The expression of Dsg1, Dsg2, and Dsg3 in pancreatic tissues was examined by immunohistochemistry and their expression in two pancreatic cancer cell lines, BxPC-3 and Panc-1, was determined by western blot analysis. …”
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998por Walsh, Naomi, O'Donovan, Norma, Kennedy, Susan, Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul“…BACKGROUND: Markers of pancreatic cancer invasion were investigated in two clonal populations of the cell line, MiaPaCa-2, Clone #3 (high invasion) and Clone #8 (low invasion) using proteomic profiling of an in vitro model of pancreatic cancer. …”
Publicado 2009
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999“…BACKGROUND: Factors mediating the invasion of pancreatic cancer cells through the extracellular matrix (ECM) are not fully understood. …”
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1000“…BACKGROUND: The aim of this study was to characterise the familial association of pancreatic cancer with other malignancies. METHODS: Relative risks (RRs) of pancreatic cancer according to family history of cancer were calculated using the updated Swedish Family-Cancer Database, which includes over 11.5 million individuals. …”
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