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1021“…Forty-one patients with confirmed pancreatic cancer (PC) selected dimensions of health related to the impact of the disease. …”
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1022“…Chronic inflammation drives initiation and progression of many malignancies, including pancreatic cancer. In this issue, Liou et al. (2013. J. …”
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1023“…Pancreatic cancer is a devastating disease with dismal prognosis. …”
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1024“…Laboratory evidence of aberrant coagulation is found in the majority of patients with advanced pancreatic cancer and a clinical consequence of this is the high incidence and prevalence of vascular thromboembolic events. …”
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1025“…Despite all improvements in both surgical and other conservative therapies, pancreatic cancer is steadily associated with a poor overall prognosis and remains a major cause of cancer mortality. …”
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1026por Chu, Zhengtao, Abu-Baker, Shadi, Palascak, Mary B., Ahmad, Syed A., Franco, Robert S., Qi, Xiaoyang“…Only a small number of promising drugs target pancreatic cancer, which is the fourth leading cause of cancer deaths with a 5-year survival of less than 5%. …”
Publicado 2013
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1027por Fang, Yantian, Yao, Qizhi, Chen, Zongyou, Xiang, Jianbin, William, Fisher E., Gibbs, Richard A., Chen, Changyi“…This review aims to summarize recent advances of important genes, proteins, and microRNAs that play a critical role in the pathogenesis of pancreatic cancer, and to provide implications for personalized medicine in pancreatic cancer.…”
Publicado 2013
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1028por Folch-Puy, Emma“…We have recently demonstrated that silencing REG3β in a pancreatic cancer model impairs tumor growth by skewing macrophage polarization.…”
Publicado 2013
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1029por Neesse, Albrecht, Krug, Sebastian, Gress, Thomas M, Tuveson, David A, Michl, Patrick“…This review focuses on current and future developments in pancreatic cancer medicine, with a particular emphasis on biophysical and biochemical approaches that target the tumor microenvironment.…”
Publicado 2013
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1030“…Purpose of the review: Pancreatic cancer is extremely aggressive, forming highly chemo-resistant tumors, and has one of the worst prognoses. …”
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1031por Javle, Milind, Li, Yanan, Tan, Dongfeng, Dong, Xiaoqun, Chang, Ping, Kar, Siddhartha, Li, Donghui“…BACKGROUND: Transforming growth factor (TGF)-β signaling pathway, may act both as a tumor suppressor and as a tumor promoter in pancreatic cancer, depending on tumor stage and cellular context. …”
Publicado 2014
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1032“…Pancreatic cancer is one of the deadliest human malignancies and little progress has been achieved in its treatment over the past decades. …”
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1034por Jabbar, Karolina S., Verbeke, Caroline, Hyltander, Anders G., Sjövall, Henrik, Hansson, Gunnar C., Sadik, Riadh“…Consequently, it may improve pancreatic cancer prevention and reduce the morbidity burden of unwarranted pancreatic surgery.…”
Publicado 2014
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1035“…In this study, we investigated the effect of the water decoctions from the leaves of Taxus cuspidate on pancreatic cancer cell proliferation and the potential mechanism(s); though its antitumor activity and mechanism in vitro remain to be elucidated, the water soluble constituents from Taxus cuspidate could be used in clinical for cancer patients.…”
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1036por Chou, Angela, Waddell, Nicola, Cowley, Mark J, Gill, Anthony J, Chang, David K, Patch, Ann-Marie, Nones, Katia, Wu, Jianmin, Pinese, Mark, Johns, Amber L, Miller, David K, Kassahn, Karin S, Nagrial, Adnan M, Wasan, Harpreet, Goldstein, David, Toon, Christopher W, Chin, Venessa, Chantrill, Lorraine, Humphris, Jeremy, Mead, R Scott, Rooman, Ilse, Samra, Jaswinder S, Pajic, Marina, Musgrove, Elizabeth A, Pearson, John V, Morey, Adrienne L, Grimmond, Sean M, Biankin, Andrew V“…BACKGROUND: Pancreatic cancer is one of the most lethal and molecularly diverse malignancies. …”
Publicado 2013
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1037“…Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) are responsible for the development of pancreatic cancer. …”
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1038por Kumar, Rahul, Chaudhary, Kumardeep, Singla, Deepak, Gautam, Ankur, Raghava, Gajendra P. S.“…Pancreatic cancer remains the most devastating disease with worst prognosis. …”
Publicado 2014
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1039“…AIMS/INTRODUCTION: Pancreatic cancer (PC) is related to diabetes. Long‐standing diabetes should be a prerequisite, whereas new‐onset hyperglycemia might be a result of PC. …”
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1040por Błogowski, Wojciech, Deskur, Anna, Budkowska, Marta, Sałata, Daria, Madej-Michniewicz, Anna, Dąbkowski, Krzysztof, Dołęgowska, Barbara, Starzyńska, Teresa“…BACKGROUND/AIMS: Recent experimental studies have suggested that various cytokines may be important players in the development and progression of pancreatic cancer. However, these findings have not yet been verified in a clinical setting. …”
Publicado 2014
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