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1041“…This study was conducted to make the network of miRNAs-mRNAs interactions in pancreatic cancer as the fourth leading cause of cancer death. …”
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1042
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1043“…Clinical presentation of AIP overlaps that of pancreatic cancer (PC). Sometimes serum IgG4 and CA 19-9 levels are unable to differentiate AIP from PC. …”
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1044por Johns, Amber L, Miller, David K, Simpson, Skye H, Gill, Anthony J, Kassahn, Karin S, Humphris, Jeremy L, Samra, Jaswinder S, Tucker, Katherine, Andrews, Lesley, Chang, David K, Waddell, Nicola, Pajic, Marina, Pearson, John V, Grimmond, Sean M, Biankin, Andrew V, Zeps, Nikolajs“…METHODS: The Australian Pancreatic Cancer Genome Initiative (APGI) is an Australian contribution to the International Cancer Genome Consortium (ICGC), that involves prospective sequencing of tumor and normal genomes of study participants with pancreatic cancer in Australia. …”
Publicado 2014
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1045por Zhou, Yufeng“…Pancreatic cancer is under high mortality but has few effective treatment modalities. …”
Publicado 2014
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1046por Cardin, Dana B, Goff, Laura, Li, Chung-I, Shyr, Yu, Winkler, Charles, DeVore, Russell, Schlabach, Larry, Holloway, Melanie, McClanahan, Pam, Meyer, Krista, Grigorieva, Julia, Berlin, Jordan, Chan, EmilyEnlace del recurso
Publicado 2014
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1047“…METHODS: Here, we examined the effects of KLT on the PI3K/Akt/mTOR pathway in pancreatic cancer xenografts in mice, and assessed its therapeutic potential. …”
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1048por NINOMIYA, ITASU, YAMAZAKI, KEISUKE, OYAMA, KATSUNOBU, HAYASHI, HIRONORI, TAJIMA, HIDEHIRO, KITAGAWA, HIROHISA, FUSHIDA, SACHIO, FUJIMURA, TAKASHI, OHTA, TETSUO“…PPAR-γ ligands are known to inhibit numerous cancer cell processes, including pancreatic cancer cell proliferation through terminal differentiation. …”
Publicado 2014
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1049por Chan, Michelle T, Lim, Gareth E, Skovsø, Søs, Yang, Yu Hsuan Carol, Albrecht, Tobias, Alejandro, Emilyn U, Hoesli, Corinne A, Piret, James M, Warnock, Garth L, Johnson, James D“…However, the actions of insulin at the various stages of pancreatic cancer progression remain poorly defined. METHODS: Here, we examined the effects of a range of insulin doses on signalling, proliferation and survival in three human cell models meant to represent three stages in pancreatic cancer progression: primary pancreatic duct cells, the HPDE immortalized pancreatic ductal cell line, and the PANC1 metastatic pancreatic cancer cell line. …”
Publicado 2014
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1051por Degrate, Luca, Bagnariol, Francesca, Nobili, Cinzia, Ogolong, Patricia, Poli, Silvia, Franciosi, Claudio, Romano, Fabrizio, Caprotti, Roberto, Uggeri, FrancoEnlace del recurso
Publicado 2009
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1052
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1053“…BACKGROUND: Pancreatic cancer is one of the most common causes of cancer-related deaths in the United States, it is difficult to detect early and typically has a very poor prognosis. …”
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1054por Zechner, Dietmar, Radecke, Tobias, Amme, Jonas, Bürtin, Florian, Albert, Ann-Christin, Partecke, Lars Ivo, Vollmar, Brigitte“…BACKGROUND: We explored if known risk factors for pancreatic cancer such as type II diabetes and chronic inflammation, influence the pathophysiology of an established primary tumor in the pancreas and if administration of metformin has an impact on tumor growth. …”
Publicado 2015
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1055por Jin, Kaizhou, Luo, Guopei, Xiao, Zhiwen, Liu, Zuqiang, Liu, Chen, Ji, Shunrong, Xu, Jin, Liu, Liang, Long, Jiang, Ni, Quanxing, Yu, XianjunEnlace del recurso
Publicado 2015
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1056por Leach, Steven D.Enlace del recurso
Publicado 2015
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1057por Arem, Hannah, Yu, Kai, Xiong, Xiaoqin, Moy, Kristin, Freedman, Neal D., Mayne, Susan T., Albanes, Demetrius, Arslan, Alan A., Austin, Melissa, Bamlet, William R., Beane-Freeman, Laura, Bracci, Paige, Canzian, Federico, Cotterchio, Michelle, Duell, Eric J., Gallinger, Steve, Giles, Graham G., Goggins, Michael, Goodman, Phyllis J., Hartge, Patricia, Hassan, Manal, Helzlsouer, Kathy, Henderson, Brian, Holly, Elizabeth A., Hoover, Robert, Jacobs, Eric J., Kamineni, Aruna, Klein, Alison, Klein, Eric, Kolonel, Laurence N., Li, Donghui, Malats, Núria, Männistö, Satu, McCullough, Marjorie L., Olson, Sara H., Orlow, Irene, Peters, Ulrike, Petersen, Gloria M., Porta, Miquel, Severi, Gianluca, Shu, Xiao-Ou, Visvanathan, Kala, White, Emily, Yu, Herbert, Zeleniuch-Jacquotte, Anne, Zheng, Wei, Tobias, Geoffrey S., Maeder, Dennis, Brotzman, Michelle, Risch, Harvey, Sampson, Joshua N., Stolzenberg-Solomon, Rachael Z.“…Our study included 3,583 pancreatic cancer cases and 7,053 controls from the genome-wide association studies of pancreatic cancer PanScans-I-III. …”
Publicado 2015
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1059“…Enhanced efforts to target subsets of patients with pancreatic cancer in order to optimize therapy benefit are warranted.…”
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1060“…FOLFIRINOX (FFX) was introduced to clinical practice in 2010 following publication of the PRODIGE 4/ACCORD 11 study, which compared this novel regimen to gemcitabine in metastatic pancreatic cancer. Median overall survival, progression-free survival, and objective responses were all superior with FFX and there was improved time to definitive deterioration in quality of life. …”
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