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1121por Kamerkar, Sushrut, LeBleu, Valerie S., Sugimoto, Hikaru, Yang, Sujuan, Ruivo, Carolina F., Melo, Sonia A., Lee, J. Jack, Kalluri, Raghu“…The mutant form of the GTPase KRAS is a key driver of pancreatic cancer but remains a challenging therapeutic target. …”
Publicado 2017
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1122por Mohamadkhani, Ashraf, Pourshams, Akram, Viti, Jessica, Cellai, Filippo, Mortazavi, Kamran, Sharafkhah, Maryam, Sotoudeh, Masoud, Malekzadeh, Reza, Boffetta, Paolo, Peluso, Marco“…A number of conditional regression models confirmed associations of pancreatic cancer with oxidative DNA damage in peripheral leukocytes. …”
Publicado 2017
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1123por Zaytouni, Tamara, Tsai, Pei-Yun, Hitchcock, Daniel S., DuBois, Cory D., Freinkman, Elizaveta, Lin, Lin, Morales-Oyarvide, Vicente, Lenehan, Patrick J., Wolpin, Brian M., Mino-Kenudson, Mari, Torres, Eduardo M., Stylopoulos, Nicholas, Clish, Clary B., Kalaany, Nada Y.“…The specific dependency of PDA on ARG2 rather than the principal hepatic enzyme ARG1 opens a therapeutic window for obesity-associated pancreatic cancer.…”
Publicado 2017
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1124“…DISCUSSION: Irreversible electroporation for locally advanced pancreatic cancer is an emerging technique which attempts to improve local control of locally advanced, non-metastatic pancreatic cancer. …”
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1125por Brauswetter, Diána, Gurbi, Bianka, Varga, Attila, Várkondi, Edit, Schwab, Richárd, Bánhegyi, Gábor, Fábián, Orsolya, Kéri, György, Vályi-Nagy, István, Peták, István“…Pancreatic cancer is an increasing cause of cancer related death worldwide. …”
Publicado 2017
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1126por Mehta, Khyati Y., Wu, Hung-Jen, Menon, Smrithi S., Fallah, Yassi, Zhong, Xiaogang, Rizk, Nasser, Unger, Keith, Mapstone, Mark, Fiandaca, Massimo S., Federoff, Howard J., Cheema, Amrita K.“…Pancreatic cancer (PC) is an aggressive disease with high mortality rates, however, there is no blood test for early detection and diagnosis of this disease. …”
Publicado 2017
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1127“…Positive results have been reported with the use of targeted therapies, particularly poly (ADP-ribose) polymerase inhibitors in BRCA-mutated ovarian and breast cancers, and their use is currently being investigated in germline-mutated pancreatic cancer. The aim of this review is to provide an outline of germline DNA damage repair mutations in pancreatic cancer and their effect on the incidence, outcomes and responses to different therapeutic options.…”
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1128por Kenner, Barbara J., Go, Vay Liang W., Chari, Suresh T., Goldberg, Ann E., Rothschild, Laura J.“…A diagnosis of pancreatic cancer is devastating owing to its poor prognosis, with a 5-year survival rate of only 9%. …”
Publicado 2017
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1130por González-Santiago, Omar, Yeverino-Gutiérrez, Myrna L, del Rosario González-González, María, Corral-Symes, Ruth, Morales-San-Claudio, Pilar C“…The five-year survival rate remains low for pancreatic cancer (PC). The objective of this study was to describe PC mortality rates in Mexico and its seven socioeconomic regions. …”
Publicado 2017
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1132por Nogueira, Leticia, Stolzenberg-Solomon, Rachael, Gamborg, Michael, Sørensen, Thorkild IA, Baker, Jennifer L“…Background: Excess weight in adulthood is one of the few modifiable risk factors for pancreatic cancer, and height has associations as well. …”
Publicado 2017
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1133“…An increase of our knowledge in lipid metabolism in pancreatic cancer cells and in tumor stroma is important for developing novel strategies of future individualized therapies of pancreatic cancer.…”
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1134por Bauer, Andrea S., Nazarov, Petr V., Giese, Nathalia A., Beghelli, Stefania, Heller, Anette, Greenhalf, William, Costello, Eithne, Muller, Arnaud, Bier, Melanie, Strobel, Oliver, Hackert, Thilo, Vallar, Laurent, Scarpa, Aldo, Büchler, Markus W., Neoptolemos, John P., Kreis, Stephanie, Hoheisel, Jörg D.Enlace del recurso
Publicado 2017
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1135por Ansari, Daniel, Friess, Helmut, Bauden, Monika, Samnegård, Johan, Andersson, Roland“…Pancreatic cancer is known for its propensity to metastasize. …”
Publicado 2018
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1136por Ding, Song-Ming, Lu, Ai-Li, Zhang, Wu, Zhou, Lin, Xie, Hai-Yang, Zheng, Shu-Sen, Li, Qi-Yong“…However, few studies have explored the role of MRC-5 in pancreatic cancer (PC). In this study, we examined the exact role and associated mechanisms of MRC-5. …”
Publicado 2018
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1137por Jiang, Weiliang, Yuan, Qiongying, Jiang, Yuanye, huang, Li, Chen, Congying, Hu, Guoyong, Wan, Rong, Wang, Xingpeng, Yang, Lijuan“…Pancreatic cancer (PC) is an aggressive malignancy associated with a poor prognosis and low responsiveness to chemotherapy and radiotherapy. …”
Publicado 2018
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1138por White, Michael, Freistaedter, Andrew, Jones, Gwendolyn J. B., Zervos, Emmanuel, Roper, Rachel L.“…Pancreatic cancer is the 5(th) leading cause of cancer deaths, and there are no effective treatments. …”
Publicado 2018
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1139“…Pancreatic cancer is characterized by mutated signaling pathways and a high incidence of drug resistance. …”
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1140por Kumari, Sonam, Khan, Sheema, Gupta, Subash C., Kashyap, Vivek K., Yallapu, Murali M., Chauhan, Subhash C., Jaggi, Meena“…MUC13 functionally interacts and stabilizes Glut-1 to instigate downstream events responsible for higher glucose uptake in pancreatic cancer cells. Altered MUC13 expression by overexpression and knockdown techniques effectively modulated glucose uptake, lactate secretion, and metastatic phenotypes in pancreatic cancer cells. …”
Publicado 2018
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