Mostrando 1,121 - 1,140 Resultados de 15,611 Para Buscar '"pancreatic cancer"', tiempo de consulta: 0.79s Limitar resultados
  1. 1121
    “…The mutant form of the GTPase KRAS is a key driver of pancreatic cancer but remains a challenging therapeutic target. …”
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  2. 1122
    “…A number of conditional regression models confirmed associations of pancreatic cancer with oxidative DNA damage in peripheral leukocytes. …”
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  3. 1123
  4. 1124
    por Orcutt, Sonia, Kis, Bela, Malafa, Mokenge
    Publicado 2017
    “…DISCUSSION: Irreversible electroporation for locally advanced pancreatic cancer is an emerging technique which attempts to improve local control of locally advanced, non-metastatic pancreatic cancer. …”
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  5. 1125
  6. 1126
    “…Pancreatic cancer (PC) is an aggressive disease with high mortality rates, however, there is no blood test for early detection and diagnosis of this disease. …”
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  7. 1127
    “…Positive results have been reported with the use of targeted therapies, particularly poly (ADP-ribose) polymerase inhibitors in BRCA-mutated ovarian and breast cancers, and their use is currently being investigated in germline-mutated pancreatic cancer. The aim of this review is to provide an outline of germline DNA damage repair mutations in pancreatic cancer and their effect on the incidence, outcomes and responses to different therapeutic options.…”
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  8. 1128
    “…A diagnosis of pancreatic cancer is devastating owing to its poor prognosis, with a 5-year survival rate of only 9%. …”
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  9. 1129
  10. 1130
    “…The five-year survival rate remains low for pancreatic cancer (PC). The objective of this study was to describe PC mortality rates in Mexico and its seven socioeconomic regions. …”
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  11. 1131
  12. 1132
    “…Background: Excess weight in adulthood is one of the few modifiable risk factors for pancreatic cancer, and height has associations as well. …”
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  13. 1133
    “…An increase of our knowledge in lipid metabolism in pancreatic cancer cells and in tumor stroma is important for developing novel strategies of future individualized therapies of pancreatic cancer.…”
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  14. 1134
  15. 1135
  16. 1136
    “…However, few studies have explored the role of MRC-5 in pancreatic cancer (PC). In this study, we examined the exact role and associated mechanisms of MRC-5. …”
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  17. 1137
    “…Pancreatic cancer (PC) is an aggressive malignancy associated with a poor prognosis and low responsiveness to chemotherapy and radiotherapy. …”
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  18. 1138
  19. 1139
    “…Pancreatic cancer is characterized by mutated signaling pathways and a high incidence of drug resistance. …”
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  20. 1140
    “…MUC13 functionally interacts and stabilizes Glut-1 to instigate downstream events responsible for higher glucose uptake in pancreatic cancer cells. Altered MUC13 expression by overexpression and knockdown techniques effectively modulated glucose uptake, lactate secretion, and metastatic phenotypes in pancreatic cancer cells. …”
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