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1161“…The poor treatment outcomes of pancreatic cancer are linked to an enrichment of cancer stem cells (CSCs) in these tumors, which are resistant to chemotherapy and promote metastasis and tumor recurrence. …”
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1162por Matkar, Pratiek N., Jong, Eric D., Ariyagunarajah, Ramya, Prud'homme, Gerald J., Singh, Krishna K., Leong‐Poi, Howard“…Recent findings have indicated that NRPs are abundantly expressed in pancreatic cancer cell lines and pancreatic tumor tissues, where they mediate several essential cancer‐initiating and cancer‐promoting functional responses through their unique ability to bind multiple ligands. …”
Publicado 2018
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1163por Sun, Qiqing, Zhang, Bo, Hu, Qiangsheng, Qin, Yi, Xu, Wenyan, Liu, Wensheng, Yu, Xianjun, Xu, JinEnlace del recurso
Publicado 2018
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1164“…FGF10 is also implicated in pancreatic cancer, and that overexpression of FGFR2b is associated with metastatic invasion. …”
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1165“…AIM: To determine whether it is possible to identify different immune phenotypic subpopulations of cancer-associated fibroblasts (CAFs) in pancreatic cancer (PC). METHODS: We defined four different stromal compartments in surgical specimens with PC: The juxtatumoural, peripheral, lobular and septal stroma. …”
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1166“…Therefore, targeting CAFs may serve as a powerful weapon against pancreatic cancer and improve therapeutic effects. However, a previous study aiming to deplete CAFs by inhibiting sonic Hedgehog signaling failed to show any benefit in survival time of pancreatic cancer patients. …”
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1167por Cascetta, Priscilla, Cavaliere, Alessandro, Piro, Geny, Torroni, Lorena, Santoro, Raffaela, Tortora, Giampaolo, Melisi, Davide, Carbone, CarmineEnlace del recurso
Publicado 2018
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1168por Khanna, Amit, Mahalingam, Kulandaivelu, Chakrabarti, Debarshi, Periyasamy, Giridharan“…This study examines a hypothesis that implicates Ets-1 in the development of gemcitabine-resistance in pancreatic cancer cells. Ets-1 protein expression was assessed in parental pancreatic cancer cells and their gemcitabine-resistant clones. …”
Publicado 2010
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1169“…Glucose transporter 1 is upregulated in pancreatic cancer, enables rapid cellular uptake of glucose, and contributes to the invasiveness and metastatic ability of the disease. …”
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1170“…Pancreatic cancer (PC) induced cachexia is a complex metabolic syndrome associated with significantly increased morbidity and mortality and reduced quality of life. …”
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1173“…Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide. …”
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1174por Kim, Laurence, Nguyen, Nam, Singhal, Nimit, Phan, Vinh‐An, Iankov, Ivan, Le, Hien“…INTRODUCTION: The majority of pancreatic cancers present locally advanced and carry a high mortality rate. …”
Publicado 2018
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1175por Ehrenberg, Karl Roland, Gao, Jianpeng, Oppel, Felix, Frank, Stephanie, Kang, Na, Kindinger, Tim, Dieter, Sebastian M., Herbst, Friederike, Möhrmann, Lino, Dubash, Taronish D., Schulz, Erik R., Strakerjahn, Hendrik, Giessler, Klara M., Weber, Sarah, Oberlack, Ava, Rief, Eva-Maria, Strobel, Oliver, Bergmann, Frank, Lasitschka, Felix, Weitz, Jürgen, Glimm, Hanno, Ball, Claudia R.“…In highly aggressive malignancies like pancreatic cancer (PC), patient-derived tumor models can serve as disease-relevant models to understand disease-related biology as well as to guide clinical decision-making. …”
Publicado 2019
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1177por Idachaba, Samuel, Dada, Oluwafemi, Abimbola, Olalekan, Olayinka, Olamide, Uma, Akunnaya, Olunu, Esther, Fakoya, Adegbenro Omotuyi John“…Pancreatic cancer ranks among the causes of cancer-related deaths. …”
Publicado 2019
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1178por Lankadasari, Manendra Babu, Mukhopadhyay, Pramiti, Mohammed, Sabira, Harikumar, Kuzhuvelil B.“…Among all the deadly cancers, pancreatic cancer ranks seventh in mortality. The absence of any grave symptoms coupled with the unavailability of early prognostic and diagnostic markers make the disease incurable in most of the cases. …”
Publicado 2019
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1179por Jeon, Yun Ho, Ha, Mihyang, Kim, Sung Won, Kim, Mun Ju, Lee, Chi-Seung, Oh, Chang-Kyu, Han, Myoung-Eun, Oh, Sae-Ock, Kim, Yun Hak“…With the growing requirement for novel prognostic biomarkers for pancreatic cancer, many studies have focused on clinical and/or genomic variables. …”
Publicado 2019
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1180por Jung, Jinhong, Yoon, Sang Min, Park, Jin-hong, Seo, Dong-Wan, Lee, Sang Soo, Kim, Myung-Hwan, Lee, Sung Koo, Park, Do Hyun, Song, Tae Jun, Ryoo, Baek-Yeol, Chang, Heung-Moon, Kim, Kyu-pyo, Yoo, Changhoon, Jeong, Jae Ho, Kim, Song Cheol, Hwang, Dae Wook, Lee, Jae Hoon, Song, Ki Byung, Jo, Yoon Young, Park, Jongmoo, Kim, Jong Hoon“…PURPOSE: Stereotactic body radiation therapy (SBRT) is a promising treatment modality for locally advanced pancreatic cancer (LAPC). We evaluated the clinical outcomes of SBRT in patients with LAPC. …”
Publicado 2019
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