Mostrando 1,201 - 1,220 Resultados de 15,611 Para Buscar '"pancreatic cancer"', tiempo de consulta: 0.35s Limitar resultados
  1. 1201
    “…Background: Pancreatic cancer is a catastrophic disease with high recurrence and death rates, even in early stages. …”
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  2. 1202
    por Furuse, Junji
    Publicado 2019
    “…Systemic chemotherapy plays an important role in the treatment of pancreatic cancer, to improve the survival of patients with pancreatic cancer. …”
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  3. 1203
  4. 1204
    “…We showed that, in one patient with pancreatic cancer, the expression of a truncated form of SPOP (p.Q360*) lacking the nuclear localization signal led to nuclear accumulation of NANOG, which promoted growth and metastasis of pancreatic cancer cells. …”
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  5. 1205
    por Chawla, Akhil, Ferrone, Cristina R.
    Publicado 2019
    “…Given the plethora of new data, there has been a shift in the paradigm of how resectable pancreatic cancer is treated at certain centers across the world. …”
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  6. 1206
    “…However, the prognostic role of serum GGT in pancreatic cancer (PC) survival lacks adequate evaluation. …”
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  7. 1207
    “…Pancreatic cancer is one of the carcinomas with the worst prognoses, as shown by its five-year survival rate of 9%. …”
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  8. 1208
    “…Pancreatic cancer is one of the most aggressive malignancies, accounting for more than 45,750 deaths annually in the U.S. alone. …”
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  9. 1209
    “…ABSTRACT: A severe lack of early diagnosis coupled with resistance to most available therapeutic options renders pancreatic cancer as a major clinical concern. The limited efficacy of current treatments necessitates the development of novel therapeutic strategies that are based on an understanding of the molecular mechanisms involved in pancreatic cancer progression. …”
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  10. 1210
    “…The KPC mouse model, driven by the Kras and Trp53 transgenes, is well regarded for faithful recapitulation of human pancreatic cancer biology. However, the extent that this model recapitulates the subclonal evolution of this tumor type is unknown. …”
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  11. 1211
  12. 1212
    “…Pancreatic cancer is an aggressive and intractable malignancy with high mortality. …”
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  13. 1213
  14. 1214
    “…Pancreatic cancer remains a devastating disease with dismal outcomes despite the development of novel chemotherapeutic regimens and radiation techniques. …”
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  15. 1215
    “…The number of patients with pancreatic cancer (PC) is currently increasing in both Korea and Japan. …”
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  16. 1216
    “…We used fluoro-5-deoxy-α-D-arabinofuranosyl)-2-nitroimidazole positron-emission tomography (FAZA-PET) imaging to quantify hypoxia before and after 5-fraction SBRT delivered to patient-derived pancreatic cancer xenografts orthotopically implanted in mice. …”
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  17. 1217
    “…Survival rates for pancreatic cancer (PC) remain dismal. Current standard of care treatment regimens provide transient clinical benefit but eventually chemoresistance develops leading to poor outcomes. …”
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  18. 1218
    “…Approximately 20% of pancreatic ductal adenocarcinoma (PDAC) patients have (borderline) resectable pancreatic cancer [(B)RPC] at diagnosis. Upfront resection with adjuvant chemotherapy has long been the standard of care for these patients. …”
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  19. 1219
    “…Pancreatic cancer is one of the most aggressive malignancies and is characterized by a low 5-year survival rate, a broad genetic diversity and a high resistance to conventional therapies. …”
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  20. 1220
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