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1281por Takahashi, Kei, Ehata, Shogo, Miyauchi, Kensuke, Morishita, Yasuyuki, Miyazawa, Keiji, Miyazono, Kohei“…Pancreatic cancer is one of the cancers with the poorest prognosis, with a 5‐year survival rate of approximately 5–10%. …”
Publicado 2020
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1282por Hang, Junjie, Lau, Steven Yuk-Fai, Yin, Ruohan, Zhu, Lina, Zhou, Siyuan, Yuan, Xin, Wu, Lixia“…Compelling evidence suggests that phosphoprotein phosphatases (PPPs) are involved in a large spectrum of physiological and pathological processes, but little is known about their roles in pancreatic cancer. We investigated the expression level, prognostic value, and potential function of PPPs with data from Oncomine, GEPIA, THPA, and TCGA databases and an independent cohort of patients with pancreatic cancer. …”
Publicado 2021
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1283“…Pancreatic cancer with synchronous liver metastasis has an extremely poor prognosis, and surgery is not recommended for such patients by the current guidelines. …”
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1284por Kimura, Nana, Yamada, Suguru, Takami, Hideki, Murotani, Kenta, Yoshioka, Isaku, Shibuya, Kazuto, Sonohara, Fuminori, Hoshino, Yui, Hirano, Katsuhisa, Watanabe, Toru, Baba, Hayato, Mori, Kosuke, Miwa, Takeshi, Kanda, Mitsuro, Hayashi, Masamichi, Matsui, Koshi, Okumura, Tomoyuki, Kodera, Yasuhiro, Fujii, Tsutomu“…SIMPLE SUMMARY: For borderline pancreatic cancer, upfront surgery was standard in the past, and the usefulness of neoadjuvant treatment has been reported in recent years. …”
Publicado 2020
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1285por Qian, Weikun, Chen, Ke, Qin, Tao, Xiao, Ying, Li, Jie, Yue, Yangyang, Zhou, Cancan, Ma, Jiguang, Duan, Wanxing, Lei, Jianjun, Han, Liang, Li, Li, Shen, Xin, Wu, Zheng, Ma, Qingyong, Wang, Zheng“…Besides, the pharmacological inhibition of EGFR suppressed the initiation of pancreatic cancer and the activation of HSF1 in vivo. Indeed, we demonstrated that the EGFR activation that mediated pancreatic cancer tumorigenesis was partly HSF1-dependent in vitro. …”
Publicado 2021
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1286por Ghidini, Michele, Lampis, Andrea, Mirchev, Milko B., Okuducu, Ali Fuat, Ratti, Margherita, Valeri, Nicola, Hahne, Jens C.“…Pancreatic cancer is one of the most aggressive malignancies with limited treatment options thus resulting in high morbidity and mortality. …”
Publicado 2020
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1287por Casolino, R., Braconi, C., Malleo, G., Paiella, S., Bassi, C., Milella, M., Dreyer, S.B., Froeling, F.E.M., Chang, D.K., Biankin, A.V., Golan, T.“…This review summarises the recent evidence on preoperative therapeutic strategies in pancreatic cancer and discusses the rationale for an imminent need for a personalised therapeutic approach in non-metastatic disease. …”
Publicado 2021
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1288
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1289por Laramie, Matthew D., Fouts, Benjamin L., MacCuaig, William M., Buabeng, Emmanuel, Jones, Meredith A., Mukherjee, Priyabrata, Behkam, Bahareh, McNally, Lacey R., Henary, MagedEnlace del recurso
Publicado 2021
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1290por Kato, Shunsuke“…However, the improvements in the prognosis of pancreatic cancer and biliary tract cancer is delayed compared to other carcinomas, and the 5-year survival rates of distal-stage disease are approximately 10 and 20%, respectively. …”
Publicado 2021
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1291por Sántha, Petra, Lenggenhager, Daniela, Finstadsveen, Anette, Dorg, Linda, Tøndel, Kristin, Amrutkar, Manoj, Gladhaug, Ivar P., Verbeke, Caroline“…SIMPLE SUMMARY: Pancreatic cancer has a poor prognosis, which is largely due to resistance to treatment. …”
Publicado 2021
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1292“…The role of ERAD inhibition in enhancing the therapeutic efficacy of FTS was further investigated in pancreatic cancer cells using pharmaceutical and genetic approaches. …”
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1293
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1294por Alpertunga, Ipek, Sadiq, Rabail, Pandya, Deep, Lo, Tammy, Dulgher, Maxim, Evans, Sarah, Bennett, Bridget, Rennert, Nancy, Frank, Richard C.Enlace del recurso
Publicado 2021
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1295por CONSTANTINESCU, ALEXANDRU, ŞANDRU, VASILE, ILIE, MADALINA, UNGUREANU, BOGDAN SILVIU, GHEONEA, DAN IONUŢ, CIUREA, TUDOREL, CAZACU, SERGIU MARIAN, VERE, CRISTIN-CONSTANTIN, CONSTANTINESCU, GABRIEL“…Conclusions: Malignant obstruction secondary to pancreatic cancer is amenable by ERCP. However, choosing the right stents still varies. …”
Publicado 2020
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1296“…These findings suggest that pathogenic ATM alterations may be prognostic for improved outcomes in patients with pancreatic cancer.…”
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1297
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1298“…The aim of this review was to summarize knowledge about IL-4 and IL-13 and their receptors in pancreatic cancer in order understand the implication of IL-4 and IL-13 and their receptors for pancreatic tumorigenesis and progression and for developing possible new diagnostic and therapeutic targets.…”
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1299por Iwasaki, Eisuke, Fukuhara, Seiichiro, Horibe, Masayasu, Kawasaki, Shintaro, Seino, Takashi, Takimoto, Yoichi, Tamagawa, Hiroki, Machida, Yujiro, Kayashima, Atsuto, Noda, Marin, Hayashi, Hideyuki, Kanai, Takanori“…Pancreatic cancer is the most lethal solid malignancy, and the number of patients with pancreatic cancer is increasing. …”
Publicado 2021
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1300“…SIMPLE SUMMARY: Improving outcomes in pancreatic cancer is achievable through the accumulation of marginal gains. …”
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