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1381“…Interventional EUS has modified the therapeutic approach, primarily for advanced pancreatic cancer. EUS-guided fiducial placement for local targeted radiotherapy treatment or EUS-guided radiofrequency ablation has been developed for local treatment, especially for patients with pancreatic cancer not suitable for surgical resection. …”
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1382por Wirth, MatthiasEnlace del recurso
Publicado 2022
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1383por Du, Jiali, Gu, Jichun, Deng, Junyuan, Kong, Lei, Guo, Yujie, Jin, Chen, Bao, Yun, Fu, Deliang, Li, Ji“…BACKGROUND: Sodium glucose transporters (SGLTs) play vital roles in glucose uptake in many solid cancers, including pancreatic cancer (PC). However, their expression profile in pancreatic cancer and correlation with prognosis are not clear. …”
Publicado 2022
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1384por Zhai, Shuyu, Huo, Zhen, Wang, Yue, Qian, Hao, Zhao, Shulin, Shi, Yusheng, Weng, Yuanchi, Deng, Xiaxing, Shen, Baiyong“…BACKGROUND: Pancreatic cancer is a highly aggressive cancer featured by early metastasis and multiple chemoresistance. …”
Publicado 2019
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1385por Roeyen, G., Berrevoet, F., Borbath, I., Geboes, K., Peeters, M., Topal, B., Van Cutsem, E., Van Laethem, J.-L.“…Pancreatic exocrine insufficiency (PEI) is a common condition in patients with pancreatic cancer (PC). PEI can be due to the tumor, which, if located in the head, causes obstruction of the pancreatic duct with subsequent atrophy of the pancreatic parenchyma, or it can be the consequence of pancreatic surgical resection. …”
Publicado 2022
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1386por Hinzman, Charles P, Bansal, Shivani, Li, Yaoxiang, Banerjee, Partha, Cheema, Amrita“…The purpose of this study was to perform qualitative and quantitative characterization of small-molecule profiles of EVs derived from various pancreatic cancer (PC) and normal pancreas cell lines, to provide proof-of-concept for evaluating the efficacy of leveraging EVs as potential biomarkers of PDAC. …”
Publicado 2020
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1387por Yeo, Dannel, Bastian, Althea, Strauss, Heidi, Saxena, Payal, Grimison, Peter, Rasko, John E. J.“…Pancreatic ductal adenocarcinoma (PDAC) is the most frequent pancreatic cancer type, characterized by a dismal prognosis due to late diagnosis, frequent metastases, and limited therapeutic response to standard chemotherapy. …”
Publicado 2022
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1388por Jaaks, Patricia, Coker, Elizabeth A., Vis, Daniel J., Edwards, Olivia, Carpenter, Emma F., Leto, Simonetta M., Dwane, Lisa, Sassi, Francesco, Lightfoot, Howard, Barthorpe, Syd, van der Meer, Dieudonne, Yang, Wanjuan, Beck, Alexandra, Mironenko, Tatiana, Hall, Caitlin, Hall, James, Mali, Iman, Richardson, Laura, Tolley, Charlotte, Morris, James, Thomas, Frances, Lleshi, Ermira, Aben, Nanne, Benes, Cyril H., Bertotti, Andrea, Trusolino, Livio, Wessels, Lodewyk, Garnett, Mathew J.“…Here we evaluate the potency and efficacy of 2,025 clinically relevant two-drug combinations, generating a dataset encompassing 125 molecularly characterized breast, colorectal and pancreatic cancer cell lines. We show that synergy between drugs is rare and highly context-dependent, and that combinations of targeted agents are most likely to be synergistic. …”
Publicado 2022
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1389por Papadakos, Stavros P., Dedes, Nikolaos, Pergaris, Alexandros, Gazouli, Maria, Theocharis, Stamatios“…This review aims to summarize the current pre-clinical and clinical evidence regarding the effects of exosomal applications in the timely diagnosis, prognosis, and therapeutic management of pancreatic cancer.…”
Publicado 2022
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1390“…Research from epidemiologic studies and experimental animal models provide insights into the role of pancreatic steatosis in the development of pancreatic cancer. Epidemiologic data demonstrate that pancreatic steatosis is widely prevalent and significantly associated with both development and progression of pancreatic cancer. …”
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1391por Pekarek, Leonel, Fraile-Martinez, Oscar, Garcia-Montero, Cielo, Saez, Miguel A., Barquero-Pozanco, Ines, del Hierro-Marlasca, Laura, de Castro Martinez, Patricia, Romero-Bazán, Adoración, Alvarez-Mon, Miguel A., Monserrat, Jorge, García-Honduvilla, Natalio, Buján, Julia, Alvarez-Mon, Melchor, Guijarro, Luis G., Ortega, Miguel A.“…SIMPLE SUMMARY: Pancreatic cancer is one of the most heterogeneous and aggressive tumours that exist. …”
Publicado 2022
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1392por Liang, Xiaoqiang, Hu, Cheng, Han, Mian, Liu, Congying, Sun, Xun, Yu, Kui, Gu, Honggang, Zhang, Jingzhe“…Pancreatic cancer is a highly fatal malignant tumor of the digestive system. …”
Publicado 2022
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1393por Moningi, Shalini, Lei, Xiudong, Fang, Penny, Taniguchi, Cullen M., Holliday, Emma B., Koay, Eugene J., Koong, Albert C., Ludmir, Ethan B., Minsky, Bruce D., Das, Prajnan, Giordano, Sharon H., Smith, Grace L.“…BACKGROUND: We assessed radiation treatment (RT) use and complications for unresectable pancreatic cancer in the US, comparing conventionally fractionated (CFRT) and stereotactic body radiation treatment (SBRT) to inform real-world expected outcomes and practice. …”
Publicado 2022
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1394“…OBJECTIVE: Pancreatic cancer is one of the deadliest solid malignancies. …”
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1395“…BACKGROUND: Pancreatic cancer patients often present with complications, which can impact treatment tolerance. …”
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1396por Porta, Miquel, Gasull, Magda, Pumarega, José, Kiviranta, Hannu, Rantakokko, Panu, Raaschou-Nielsen, Ole, Bergdahl, Ingvar A, Sandanger, Torkjel Manning, Agudo, Antoni, Rylander, Charlotta, Nøst, Therese Haugdahl, Donat-Vargas, Carolina, Aune, Dagfinn, Heath, Alicia K, Cirera, Lluís, Goñi-Irigoyen, Fernando, Alguacil, Juan, Giménez-Robert, Àlex, Tjønneland, Anne, Sund, Malin, Overvad, Kim, Mancini, Francesca Romana, Rebours, Vinciane, Boutron-Ruault, Marie-Christine, Kaaks, Rudolf, Schulze, Matthias B, Trichopoulou, Antonia, Palli, Domenico, Grioni, Sara, Tumino, Rosario, Naccarati, Alessio, Panico, Salvatore, Vermeulen, Roel, Quirós, J Ramón, Rodríguez-Barranco, Miguel, Colorado-Yohar, Sandra M, Chirlaque, María-Dolores, Ardanaz, Eva, Wareham, Nick, Key, Tim, Johansson, Mattias, Murphy, Neil, Ferrari, Pietro, Huybrechts, Inge, Chajes, Veronique, Gonzalez, Carlos Alberto, Bueno-de-Mesquita, Bas, Gunter, Marc, Weiderpass, Elisabete, Riboli, Elio, Duell, Eric J, Katzke, Verena, Vineis, Paolo“…BACKGROUND: Findings and limitations of previous studies on persistent organic pollutants (POPs) and pancreatic cancer risk support conducting further research in prospective cohorts. …”
Publicado 2021
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1397por Merz, Valeria, Mangiameli, Domenico, Zecchetto, Camilla, Quinzii, Alberto, Pietrobono, Silvia, Messina, Carlo, Casalino, Simona, Gaule, Marina, Pesoni, Camilla, Vitale, Pasquale, Trentin, Chiara, Frisinghelli, Michela, Caffo, Orazio, Melisi, Davide“…The mainstay treatment for patients with immediate resectable pancreatic cancer remains upfront surgery, which represents the only potentially curative strategy. …”
Publicado 2022
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1398por Dai, Hong, Abdullah, Razack, Wu, Xiaoqiu, Li, Fangfei, Ma, Yuan, Lu, Aiping, Zhang, Ge“…Pancreatic cancer (PC) is one of the most lethal cancers with an almost 10% 5-year survival rate. …”
Publicado 2022
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1399“…Sadly, the use of immunotherapy has yet to bring significant clinical breakthrough among pancreatic cancer patients, suggesting that pancreatic cancer has successfully evaded immunomodulation. …”
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1400por Hafiz, Sabrina S., Xavierselvan, Marvin, Gokalp, Sumeyra, Labadini, Daniela, Barros, Sebastian, Duong, Jeanne, Foster, Michelle, Mallidi, Srivalleesha“…Herein, we present a drug delivery strategy for photosensitizers based on a new liquid metal nanoplatform that leverages the tumor microenvironment to achieve photodynamic therapeutic effects in pancreatic cancer. Eutectic gallium indium (EGaIn) nanoparticles were successfully conjugated with a water-soluble cancer targeting ligand, hyaluronic acid, and a photosensitizer, benzoporphyrin derivative, creating EGaIn nanoparticles (EGaPs) via a simple green sonication method. …”
Publicado 2022
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