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  1. 1481
    “…SIMPLE SUMMARY: Malignant tumors, especially pancreatic cancer, are the major contributors to cancer mortality worldwide, and their effective treatments are still limited. …”
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    Immune Checkpoint Neuropilins as Novel Biomarkers and Therapeutic Targets for Pancreatic Cancer
  2. 1482
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    EGFR Reloaded: Finding New Ways to Shape Pancreatic Cancer Epigenome
  3. 1483
    “…Finally, we demonstrated >80% selective cell death of two targeted pancreatic cancer cell lines in co-cultures using 4–9 sgRNAs, targeting noncoding regions, designed from the somatic PAM discovery approach. …”
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    CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers
  4. 1484
    “…S100A4 may be a useful biomarker for predicting EMT state, disease progression, and outcome in patients with pancreatic cancer. [Image: see text]…”
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    S100 family proteins are linked to organoid morphology and EMT in pancreatic cancer
  5. 1485
    “…BACKGROUND: Pancreatic cancer (PC) is one of the most aggressive cancers worldwide. …”
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    Genomic landscape of pancreatic cancer in the Japanese version of the Cancer Genome Atlas
  6. 1486
    “…As the cell-autonomous role of adenosine signaling through Adora2b has not been comprehensively studied in pancreatic cancer cells, we will also discuss published data from other malignancies to infer emerging therapeutic considerations for targeting the Adora2b adenosine receptor to reduce the proliferative, invasive, and metastatic potential of PDAC cells.…”
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    The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer
  7. 1487
    “…All the time, pancreatic cancer is a problem worldwide because of its high degree of malignancy and increased mortality. …”
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    A neural network model to screen feature genes for pancreatic cancer
  8. 1488
    “…Nevertheless, the functions of different STATs in pancreatic cancer (PC) and their relationship to the prognosis and immune infiltration as well as drug efficacy in PC patients have not been systematically elucidated. …”
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    The predictive value of prognosis and therapeutic response for STAT family in pancreatic cancer
  9. 1489
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    Effects of cancer stigma on quality of life of patients with hepatobiliary and pancreatic cancer
  10. 1490
    “…In this paper, Au nanocages (AuNCs) loaded with the MRI contrast agent gadolinium (Gd) and capped with the tumor-targeting gene survivin (Sur–AuNC•Gd–Cy7 nanoprobes) were designed and applied as a targeted imaging agent for pancreatic cancer. With its capacity to transport fluorescent dyes and MR imaging agents, the gold cage is an outstanding platform. …”
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    A Gold Nanocage Probe Targeting Survivin for the Diagnosis of Pancreatic Cancer
  11. 1491
    “…The most typical case is the occurrence and development of cancer. Pancreatic cancer (PC), one of the most aggressive and lethal types of cancer, has recently attracted the attention of researchers. …”
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    Microbiota Regulates Pancreatic Cancer Carcinogenesis through Altered Immune Response
  12. 1492
    “…INTRODUCTION: Pancreatic cancer has one of the worst prognoses of all cancers. …”
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    Intratumoral injection therapies for locally advanced pancreatic cancer: systematic review
  13. 1493
    “…The practice of precision therapy in pancreatic cancer was limited by the paucity of targetable genetic alterations, especially in the Asian population. …”
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    Pathogenic genomic alterations in Chinese pancreatic cancer patients and their therapeutical implications
  14. 1494
    “…INTRODUCTION: National Comprehensive Cancer Network (NCCN) 2019 Guidelines recommend universal germline (GL) testing for patients (pts) with pancreatic cancer (PC), given germline mutations (gMut) can occur at a similar rate irrespective of an individual’s family history of cancer. …”
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    Adherence to NCCN Genetic Testing Guidelines in Pancreatic Cancer and Impact on Treatment
  15. 1495
    “…To investigate this metabolic function, we used a genetic and a pharmacologic approach to target Arg1 in pancreatic cancer. Genetic inactivation of Arg1 in macrophages, using a dual recombinase genetically engineered mouse model of pancreatic cancer, delayed formation of invasive disease, while increasing CD8(+) T cell infiltration. …”
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    Arginase 1 is a key driver of immune suppression in pancreatic cancer
  16. 1496
    por Kikuyama, Masataka
    Publicado 2023
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    A Novel Diagnostic Imaging Method for the Early Detection of Pancreatic Cancer
  17. 1497
    “…Pancreatic cancer is a strongly malignant gastrointestinal carcinoma characterized by late detection, high mortality rates, poor patient prognosis and lack of effective treatments. …”
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    Pancreatic stellate cells in pancreatic cancer: as potential targets for future therapy
  18. 1498
    “…Pancreatic cancer stem cells (CSCs) play a key role in the initiation and progression of pancreatic adenocarcinoma (PDAC). …”
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    Role of RNA methylation in the regulation of pancreatic cancer stem cells (Review)
  19. 1499
    “…METHODS: All cases of locally advanced or metastatic pancreatic cancer treated with the SOXIRI or mFOLFIRINOX regimen in Sun Yat-sen University Cancer Centre from July 2012 to June 2021 were reviewed retrospectively. …”
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    Efficacy and safety of SOXIRI versus mFOLFIRINOX in advanced pancreatic cancer
  20. 1500
    “…The quality of US images using conventional probes highly depends on user proficiency and anatomical changes, which has severely hindered the use of US-based organ motion monitoring for pancreatic cancer. The flexible array transducer is a novel and promising solution to address the limitation of conventional US probes. …”
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    Ultrasound Imaging with Flexible Array Transducer for Pancreatic Cancer Radiation Therapy
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