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1521por Irajizad, Ehsan, Kenney, Ana, Tang, Tiffany, Vykoukal, Jody, Wu, Ranran, Murage, Eunice, Dennison, Jennifer B., Sans, Marta, Long, James P., Loftus, Maureen, Chabot, John A., Kluger, Michael D., Kastrinos, Fay, Brais, Lauren, Babic, Ana, Jajoo, Kunal, Lee, Linda S., Clancy, Thomas E., Ng, Kimmie, Bullock, Andrea, Genkinger, Jeanine M., Maitra, Anirban, Do, Kim-Anh, Yu, Bin, Wolpin, Brian M., Hanash, Sam, Fahrmann, Johannes F.“…Emerging evidence implicates microbiome involvement in the development of pancreatic cancer (PaCa). Here, we investigate whether increases in circulating microbial-related metabolites associate with PaCa risk by applying metabolomics profiling to 172 sera collected within 5 years prior to PaCa diagnosis and 863 matched non-subject sera from participants in the Prostate, Lung, Colorectal, and Ovarian (PLCO) cohort. …”
Publicado 2023
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1522“…SLE-associated pancreatitis is uncommon, and pancreatic cancer in SLE is very rare. Imaging findings in SLE with pancreatitis can mimic malignancy. …”
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1523por Viegas, Cláudia, Patrício, Ana B., Prata, João, Fonseca, Leonor, Macedo, Ana S., Duarte, Sofia O. D., Fonte, Pedro“…Pancreatic cancer represents one of the most lethal cancer types worldwide, with a 5-year survival rate of less than 5%. …”
Publicado 2023
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1524por Du, Jian, Tang, Bo, Wang, Jingwen, Sui, Hongtao, Jin, Xueli, Wang, Liming, Wang, ZhongyuEnlace del recurso
Publicado 2023
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1525por Khojasteh-Leylakoohi, Fatemeh, Mohit, Reza, Khalili-Tanha, Nima, Asadnia, Alireza, Naderi, Hamid, Pourali, Ghazaleh, Yousefli, Zahra, Khalili-Tanha, Ghazaleh, Khazaei, Majid, Maftooh, Mina, Nassiri, Mohammadreza, Hassanian, Seyed Mahdi, Ghayour-Mobarhan, Majid, Ferns, Gordon A., Shahidsales, Soodabeh, Lam, Alfred King-yin, Giovannetti, Elisa, Nazari, Elham, Batra, Jyotsna, Avan, Amir“…To identify DEGs, genome RNA sequencing and clinical data from pancreatic cancer patients were extracted from The Cancer Genome Atlas Database (TCGA). …”
Publicado 2023
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1526“…Targeting immunogenic cell death (ICD) may enable the response of pancreatic cancer to immune checkpoint inhibitors (ICIs). …”
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1527“…BACKGROUND: The relationship between red and processed meat consumption and pancreatic cancer risk is controversial and no study has looked specifically at the correlation for 6 years. …”
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1528por Caputo, Damiano, Quagliarini, Erica, Coppola, Alessandro, La Vaccara, Vincenzo, Marmiroli, Benedetta, Sartori, Barbara, Caracciolo, Giulio, Pozzi, DanielaEnlace del recurso
Publicado 2023
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1529por Maloney, Sarah, Clarke, Stephen J., Sahni, Sumit, Hudson, Amanda, Colvin, Emily, Mittal, Anubhav, Samra, Jaswinder, Pavlakis, Nick“…Despite modern advances in cancer medicine, pancreatic cancer survival remains unchanged at just 12%. …”
Publicado 2023
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1530Obstructive Jaundice Mimicking Pancreatic Cancer: An Unusual Presentation of Autoimmune Pancreatitispor Ogunlaja, Tiwalade, Oni, Efe, Ibeawuchi, Morris, Sattar, Lubna, Eshete, Filagot D, Agyebinti, Felix B“…It is known to mimic pancreatic cancer due to its similar clinical and radiological presentations. …”
Publicado 2023
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1531por Brayer, Kathryn J., Hanson, Joshua A., Cingam, Shashank, Martinez, Cathleen, Ness, Scott A., Rabinowitz, Ian“…We used RNA-sequencing to compare 14 matched tumor and normal (tumor adjacent) pancreatic cancer samples and found Malassezia RNA in both the PDAC and normal tissues. …”
Publicado 2023
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1532por Boursi, Ben, Wileyto, E. Paul, Mamtani, Ronac, Domchek, Susan M., Golan, Talia, Hood, Ryan, Reiss, Kim A.“…This cohort study compares the outcomes of patients with BRCA1 and BRCA-related pancreatic cancers using 2 large data sets.…”
Publicado 2023
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1533“…Abnormal expression and activities of both cyclooxygenases and lipoxygenases have been reported in pancreatic cancer. In this article, we aim to provide a brief summary of (1) our understanding of the roles of these enzymes in pancreatic cancer tumorigenesis and progression; and (2) the potential of using cyclooxygenase and lipoxygenase inhibitors for pancreatic cancer treatment and prevention.…”
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1534“…The early diagnosis of pancreatic cancer, as well as distinguishing between chronic pancreatitis and malignant pancreatic disease, remains still a clinical problem. …”
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1537por Barton, C. M., Staddon, S. L., Hughes, C. M., Hall, P. A., O'Sullivan, C., Klöppel, G., Theis, B., Russell, R. C., Neoptolemos, J., Williamson, R. C.“…We found immunodetectable p53 in 13 of 22 (60%) frozen pancreatic cancers and seven of 13 pancreatic cell lines. …”
Publicado 1991
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1538“…The in vivo administration of somatostatin (SS) or its analogues is capable of suppressing the growth of pancreatic cancer in experimental animals. We examined the effects of SS-14 and its analogue RC-160 on the in vitro growth of two human pancreatic cancer cell lines MiaPaCa-2 and Panc-1 stimulated with epidermal growth factor (EGF) or insulin-like growth factor 1 (IGF-1). …”
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1539por Gansauge, F., Gansauge, S., Parker, N., Beger, M. I., Poch, B., Link, K. H., Safi, F., Beger, H. G.“…We investigated the expression and release of CAM 17.1 in pancreatic carcinoma cell lines and tissue specimens of normal pancreas, chronic pancreatitis and pancreatic cancer. CAM 17.1 was weakly expressed on normal ductal cells and chronic pancreatitis, whereas it was overexpressed in pancreatic cancer. …”
Publicado 1996
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1540“…The deoxycytidine analogue 2′,2′-difluoro-2′-deoxycytidine (dFdC, gemcitabine) is a potent radiosensitiser, but has limited efficacy in combination with radiotherapy in patients with pancreatic cancer due to acute toxicity. We investigated whether cyclopentenyl cytosine (CPEC), targetting the ‘de novo’ biosynthesis of cytidine triphosphate (CTP), could increase dFdC cytotoxicity alone or in combination with irradiation in a panel of human pancreatic cancer cells (Panc-1, Miapaca-2, BxPC-3). …”
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