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1561por Angst, Eliane, Chen, Monica, Mojadidi, Michelle, Hines, O. Joe, Reber, Howard A., Eibl, Guido“…In this study, we sought to investigate pancreatic cancer angiogenesis in a genetically modified VEGFR2-luc-KI mouse. …”
Publicado 2010
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1562por Liu, Jun-Wei, Cai, Min-Xia, Xin, Ying, Wu, Qing-Song, Ma, Jun, Yang, Po, Xie, Hai-Yang, Huang, Dong-Sheng“…BACKGROUND: To explore the anti-tumor effects of parthenolide in human pancreatic cancer. METHODS: BxPC-3 cell, a human pancreatic cancer, was treated with parthenolide at different concentrations. …”
Publicado 2010
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1563por Rückert, Felix, Dawelbait, Gihan, Winter, Christof, Hartmann, Arndt, Denz, Axel, Ammerpohl, Ole, Schroeder, Michael, Schackert, Hans Konrad, Sipos, Bence, Klöppel, Günter, Kalthoff, Holger, Saeger, Hans-Detlev, Pilarsky, Christian, Grützmann, Robert“…Changes in apoptosis signaling in pancreatic cancer result in chemotherapy resistance and aggressive growth and metastasizing. …”
Publicado 2010
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1564por Garrido-Laguna, I, Tan, A C, Uson, M, Angenendt, M, Ma, W W, Villaroel, M C, Zhao, M, Rajeshkumar, N V, Jimeno, A, Donehower, R, Iacobuzio-Donahue, C, Barrett, M, Rudek, M A, Rubio-Viqueira, B, Laheru, D, Hidalgo, M“…Patients with advanced, gemcitabine-resistant pancreatic cancer were treated with sirolimus (5 mg daily). …”
Publicado 2010
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1565por George, Sherine, Bhalerao, Siddharth V, Lidstone, Erich A, Ahmad, Irfan S, Abbasi, Atiya, Cunningham, Brian T, Watkin, Kenneth L“…Our study focuses upon pancreatic cancer, due to its high mortality rate, that is attributed in part to the lack of an effective chemotherapeutic agent. …”
Publicado 2010
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1566por Su, Y, Loos, M, Giese, N, Hines, O J, Diebold, I, Görlach, A, Metzen, E, Pastorekova, S, Friess, H, Büchler, P“…EXPERIMENTAL DESIGN: PHD3 expression was analysed in human pancreatic cancer tissues and cancer cell lines by real-time quantitative PCR and immunohistochemistry. …”
Publicado 2010
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1569por Lahat, Guy, Sever, Ronen, Lubezky, Nir, Nachmany, Ido, Gerstenhaber, Fabian, Ben-Haim, Menahem, Nakache, Richard, Koriansky, Josef, Klausner, Josef M“…BACKGROUND: Compromised physiological reserve, comorbidities, and the natural history of pancreatic cancer may deny pancreatic resection from elderly patients. …”
Publicado 2011
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1570“…Superoxide plays an important role in pancreatic cancer cell proliferation and scavenging or decreasing the levels of superoxide inhibits pancreatic cancer cell growth both in vitro and in vivo. …”
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1571por Chan, Leo L., George, Sherine, Ahmad, Irfan, Gosangari, Saujanya L., Abbasi, Atiya, Cunningham, Brian T., Watkin, Kenneth L.“…In this work, rohituka and chittagonga, fractionated with petroleum ether, dichloromethane, and ethanol, were explored for their anticancer potential against two breast cancer (MCF-7 and HTB-126) and three pancreatic cancer (Panc-1, Mia-Paca2, and Capan1). The human foreskin fibroblast, Hs68, was also included. …”
Publicado 2011
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1572por Lister, Adam, Nedjadi, Taoufik, Kitteringham, Neil R, Campbell, Fiona, Costello, Eithne, Lloyd, Bryony, Copple, Ian M, Williams, Samantha, Owen, Andrew, Neoptolemos, John P, Goldring, Chris E, Park, B Kevin“…Here, we have investigated the integrity of the Nrf2/Keap1 system in pancreatic cancer. RESULTS: Keap1, Nrf2 and the Nrf2 target genes AKR1c1 and GCLC were detected in a panel of five pancreatic cancer cell lines. …”
Publicado 2011
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1573por Zhang, Kejun, Jiao, Xuelong, Liu, Xiaoyi, Zhang, Bingyuan, Wang, Jigang, Wang, Quan, Tao, Yan, Zhang, Dianliang“…The prognosis of patients with pancreatic cancer remains poor; only patients with small tumors and complete resection have a chance of a complete cure. …”
Publicado 2010
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1574por Khan, Jameel Ahmad, Kudgus, Rachel A., Szabolcs, Annamaria, Dutta, Shamit, Wang, Enfeng, Cao, Sheng, Curran, Geoffry L., Shah, Vijay, Curley, Steven, Mukhopadhyay, Debabrata, Robertson, J. David, Bhattacharya, Resham, Mukherjee, Priyabrata“…BACKGROUND: Pancreatic cancer is the fourth leading cause of cancer related deaths in America. …”
Publicado 2011
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1575por Kim, Eun Ran, Bae, Sun Youn, Lee, Kwang Hyuk, Lee, Kyu Taek, Son, Hee Jung, Rhee, Jong Chul, Lee, Jong Kyun“…Twenty patients diagnosed with pancreatic cancer were enrolled. During the same period, 40 patients were randomly selected from 2,202 patients diagnosed with pancreatic cancer at the Out Patient Clinic (OPC) for comparison. …”
Publicado 2011
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1576por Deeb, Dorrah, Gao, Xiaohua, Arbab, Ali S., Barton, Kenneth, Dulchavsky, Scott A., Gautam, Subhash C.“…Oleanolic acid-derived synthetic triterpenoids are potent antitumorigenic agents, but their efficacy or the mechanism of action for pancreatic cancer has not been adequately investigated. …”
Publicado 2010
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1577por Yachida, Shinichi, Jones, Siân, Bozic, Ivana, Antal, Tibor, Leary, Rebecca, Fu, Baojin, Kamiyama, Mihoko, Hruban, Ralph H., Eshleman, James R., Nowak, Martin A., Velculescu, Victor E., Kinzler, Kenneth W., Vogelstein, Bert, Iacobuzio-Donahue, Christine A.“…This is particularly true for pancreatic cancers, where most patients are diagnosed with metastatic disease and few show a sustained response to chemo- or radiation therapy (3). …”
Publicado 2010
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1578“…Pancreatic cancer is an aggressive solid tumour characterized by its local invasion, early metastasis and resistance to standard chemotherapy or radiation therapy. …”
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1579por Onda, Shinji, Okamoto, Tomoyoshi, Kanehira, Masaru, Fujioka, Shuichi, Harada, Tohru, Hano, Hiroshi, Fukunaga, Masaharu, Yanaga, Katsuhiko“…Autoimmune pancreatitis (AIP) can be difficult to distinguish from pancreatic cancer. We report a case of histopathologically proven AIP mimicking neuroendocrine tumor (NET) or pancreatic cancer in a 53-year-old man. …”
Publicado 2012
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1580por Fischer, Richard, Breidert, Matthias, Keck, Tobias, Makowiec, Frank, Lohrmann, Christian, Harder, Jan“…BACKGROUND/AIM: Adjuvant chemotherapy for 6 months is the current standard of care after potentially curative resection of pancreatic cancer and yields an overall survival of 15–20 months. …”
Publicado 2012
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