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1681por Wang, Oliver H., Azizian, Nancy, Guo, Ming, Capello, Michela, Deng, Defeng, Zang, Fenglin, Fry, Jason, Katz, Matthew H., Fleming, Jason B., Lee, Jeffrey E., Wolff, Robert A., Hanash, Samir, Wang, Huamin, Maitra, Anirban“…The strong associations between low MAP4K5 expression and loss of E-cadherin, reduced CES2 expression and decreased overall survival may suggest an important role of MAP4K5 in epithelial-to-mesenchymal transition, chemotherapy resistance and tumor progression in pancreatic cancer. Targeting impaired MAP4K5 signaling may represent a new therapeutic strategy for pancreatic cancer.…”
Publicado 2016
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1682“…OBJECTIVES: New-onset diabetes mellitus (NODM) in adults is often an early manifestation of pancreatic cancer (PaCa), but the incidence of PaCa in this cohort is rather low. …”
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1683por Ko, Andrew H“…As such, nal-IRI represents an important landmark in cancer drug development, and potentially ushers in a new era where a greater number of patients with advanced pancreatic cancer can be sequenced through multiple lines of therapy translating into meaningful improvements in survival.…”
Publicado 2016
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1684“…The present study identified differentially-expressed genes (DEGs) between pancreatic cancer (PC) tissues and normal tissues, and assessed genetic factors associated with the pathogenesis of PC. …”
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1685“…CONCLUSIONS: Knockdown of ZFR might provide a novel alternative to targeted therapy of pancreatic cancer and deserves further investigation.…”
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1686“…Pancreatic cancer is a leading cause of cancer-related deaths in the western world. …”
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1687“…The development of targeted agents and chemotherapies for pancreatic cancer has only modestly affected clinical outcome and not changed 5-year survival. …”
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1688por Okuno, Mitsuru, Yasuda, Ichiro, Adachi, Seiji, Nakashima, Masanori, Kawaguchi, Junji, Doi, Shinpei, Iwashita, Takuji, Hirose, Yoshinobu, Kozawa, Osamu, Yoshimi, Naoki, Shimizu, Masahito, Moriwaki, Hisataka“…BACKGROUND AND AIM: The precise role of phosphorylated heat shock protein (HSP) 27 (p-HSP27) in pancreatic cancer remains to be elucidated. The aim of this study was to investigate whether the expression of p-HSP27 predicts the prognosis of patients with pancreatic cancer. …”
Publicado 2016
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1689“…Operable pancreatic cancer is characterized by a high risk of recurrence. …”
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1690por Shakeri, Ramin, Kamangar, Farin, Mohamadnejad, Mehdi, Tabrizi, Reza, Zamani, Farhad, Mohamadkhani, Ashraf, Nikfam, Sepideh, Nikmanesh, Arash, Sotoudeh, Masoud, Sotoudehmanesh, Rasoul, Shahbazkhani, Bijan, Ostovaneh, Mohammad Reza, Islami, Farhad, Poustchi, Hossein, Boffetta, Paolo, Malekzadeh, Reza, Pourshams, Akram“…BACKGROUND AND AIMS: Although several studies have suggested opium as a risk factor for cancers of the esophagus, stomach, larynx, lung, and bladder, no previous study has examined the association of opium with pancreatic cancer. We aimed to study the association between opium use and risk of pancreatic cancer in Iran, using a case-control design. …”
Publicado 2016
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1692por Korc, MurrayEnlace del recurso
Publicado 2016
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1693por Ankeny, J S, Court, C M, Hou, S, Li, Q, Song, M, Wu, D, Chen, J F, Lee, T, Lin, M, Sho, S, Rochefort, M M, Girgis, M D, Yao, J, Wainberg, Z A, Muthusamy, V R, Watson, R R, Donahue, T R, Hines, O J, Reber, H A, Graeber, T G, Tseng, H R, Tomlinson, J SEnlace del recurso
Publicado 2016
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1694por Parsons, Henrique A., Baracos, Vickie E., Hong, David S., Abbruzzese, James, Bruera, Eduardo, Kurzrock, Razelle“…Weight loss due to fat and muscle depletion is a hallmark of pancreatic cancer and is associated with worse outcomes. …”
Publicado 2016
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1695por Zechner, Dietmar, Kroemer, Tim, Albert, Ann-Christin, Schönrogge, Maria, Radecke, Tobias, Vollmar, Brigitte“…Activation of Wnt signaling was also noticed during growth of pancreatic cancer in an orthotopic syngeneic pancreas cancer model. …”
Publicado 2016
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1696por Meyer, Kevin A., Neeley, Christopher K., Baker, Nicki A., Washabaugh, Alexandra R., Flesher, Carmen G., Nelson, Barbara S., Frankel, Timothy L., Lumeng, Carey N., Lyssiotis, Costas A., Wynn, Michelle L., Rhim, Andrew D., O’Rourke, Robert W.Enlace del recurso
Publicado 2016
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1697por Chllamma, Muralidharan K, Cook, Natalie, Dhani, Neesha C, Giby, Kazim, Dodd, Anna, Wang, Lisa, Hedley, David W, Moore, Malcolm J, Knox, Jennifer J“…METHODS: This is a retrospective review of patients treated with FOLFIRINOX for pancreatic cancer at Princess Margaret Cancer Centre, between December 2011 and July 2014. …”
Publicado 2016
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1698por Xie, Zijun, Chen, Xiaoliang, Li, Jianzhong, Guo, Yunwei, Li, Haijiao, Pan, Xuemei, Jiang, Jie, Liu, Huiling, Wu, Bin“…Sensitive and non-invasive biomarkers for pancreatic cancer (PC) are lacking. We aimed to identify salivary long non-coding RNAs (lncRNAs) as biomarkers in diagnosis of resectable PC. …”
Publicado 2016
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1700por Yin, Tao, Zhang, Zhengle, Cao, Bin, Duan, Qingke, Shi, Pengfei, Zhao, Hengqiang, Camara, Soriba Naby, Shen, Qiang, Wang, Chunyou“…As the standard therapy for pancreatic cancer, gemcitabine shows limited efficacy in pancreatic cancer patients because of chemoresistance. …”
Publicado 2016
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