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1701“…Pancreatic cancer is a formidable malignancy with poor outcomes. …”
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1702Diagnostic Value and Interreader Agreement of the Pancreaticolienal Gap in Pancreatic Cancer on MDCTpor Schawkat, Khoschy, Kühn, Wolfgang, Inderbitzin, Daniel, Gloor, Beat, Heverhagen, Johannes T., Runge, Val Murray, Christe, Andreas“…CONCLUSION: The significant interreader agreement supports the use of the PLG as a characterizing feature of pancreatic cancer independent of the tumor stage on an axial plane. …”
Publicado 2016
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1704por Chakedis, Jeffery, French, Randall, Babicky, Michele, Jaquish, Dawn, Mose, Evangeline, Cheng, Peter, Holman, Patrick, Howard, Haleigh, Miyamoto, Jaclyn, Porras, Paula, Walterscheid, Zakk, Schultz-Fademrecht, Carsten, Esdar, Christina, Schadt, Oliver, Eickhoff, Jan, Lowy, Andrew M.“…The RON tyrosine kinase receptor is under investigation as a novel target in pancreatic cancer. While RON mutations are uncommon, RON isoforms are produced in cancer cells via a variety of mechanisms. …”
Publicado 2016
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1705por Mandilaras, Victoria, Bouganim, Nathaniel, Yin, Hui, Asselah, Jamil, Azoulay, Laurent“…Recently, these drugs have been associated with a protective effect against pancreatic cancer, but data on this putative association remain limited. …”
Publicado 2017
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1706
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1707“…We hypothesized that targeting p300 can enhance the cytotoxicity of gemcitabine, which induces pancreatic cancer cell apoptosis by damaging DNA. Expression of p300 was confirmed in pancreatic cancer cell lines and human pancreatic adenocarcinoma tissues by western blotting and immunohistochemistry. …”
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1708“…Acute pancreatitis (AP) is a rare manifestation of pancreatic cancer (PC). The relationship between AP and PC remains less distinct. …”
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1709por Wang, Lei, Barth, Connor W., Sibrian-Vazquez, Martha, Escobedo, Jorge O., Lowry, Mark, Muschler, John, Li, Haiyan, Gibbs, Summer L., Strongin, Robert M.“…[Image: see text] Molecular probes that selectively highlight pancreatic cancer (PC) tissue have the potential to improve pancreatic ductal adenocarcinoma (PDAC) margin assessment through the selective highlighting of individual PC cells. …”
Publicado 2017
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1710por Wang, Jian, He, Peijun, Gaida, Matthias, Yang, Shouhui, Schetter, Aaron J., Gaedcke, Jochen, Ghadimi, B. Michael, Ried, Thomas, Yfantis, Harris, Lee, Dong, Weiss, Jonathan M., Stauffer, Jimmy, Hanna, Nader, Alexander, H. Richard, Hussain, S. Perwez“…Pancreatic cancer is one of the most lethal malignancies and is refractory to the available treatments. …”
Publicado 2016
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1711“…Pancreatic cancer is a type of common malignant tumors with high occurrence in the world. …”
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1712por Gbelcová, Helena, Rimpelová, Silvie, Ruml, Tomáš, Fenclová, Marie, Kosek, Vítek, Hajšlová, Jana, Strnad, Hynek, Kolář, Michal, Vítek, Libor“…Thus, the aim of this study was to identify the biological pathways affected by individual statins in an in vitro model of human pancreatic cancer. The study was performed on a human pancreatic cancer cell line MiaPaCa-2, exposed to all commercially available statins (12 μM, 24 h exposure). …”
Publicado 2017
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1713por Delitto, Daniel, Judge, Sarah M., Delitto, Andrea E., Nosacka, Rachel L., Rocha, Fernanda G., DiVita, Bayli B., Gerber, Michael H., George, Thomas J., Behrns, Kevin E., Hughes, Steven J., Wallet, Shannon M., Judge, Andrew R., Trevino, Jose G.“…Specifically, human PC xenografts were generated by implantation of pancreatic cancer cells, L3.6pl and PANC-1, either in the flank or orthotopically within the pancreas. …”
Publicado 2016
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1714por Subramani, Ramadevi, Gonzalez, Elizabeth, Nandy, Sushmita Bose, Arumugam, Arunkumar, Camacho, Fernando, Medel, Joshua, Alabi, Damilola, Lakshmanaswamy, Rajkumar“…INTRODUCTION: The lack of efficient treatment options for pancreatic cancer highlights the critical need for the development of novel and effective chemotherapeutic agents. …”
Publicado 2016
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1715“…The effects of IDO on pancreatic cancer are poorly understood. This study aimed to investigate the expression and prognostic significance of IDO in pancreatic cancer. …”
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1716por Sankpal, Umesh T., Goodison, Steve, Jones-Pauley, Michelle, Hurtado, Myrna, Zhang, Fan, Basha, Riyaz“…The gene expression studies identified new targets involved in TA's mode of action, while supporting the hypothesis about the association of Sp1 in TA mediated effects in pancreatic cancer.…”
Publicado 2017
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1719
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1720“…The reprogramming mechanism in pancreatic cancer involves deregulated uptake of glucose and glutamine and other opportunistic modes of satisfying energetic demands in a hypoxic and nutrient-poor environment. …”
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