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162por Johansson, Henrik, Andersson, Roland, Bauden, Monika, Hammes, Sarah, Holdenrieder, Stefan, Ansari, Daniel“…Novel treatment modalities are necessary for pancreatic cancer. Immunotherapy with immune checkpoint inhibition has shown effect in other solid tumors, and could have a place in pancreatic cancer treatment. …”
Publicado 2016
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164por Kim, George“…BACKGROUND: Nanoparticle albumin-bound paclitaxel (nab-P) plus gemcitabine (Gem) became a standard treatment option for metastatic pancreatic cancer (MPC) following positive results from a global phase III trial (MPACT). …”
Publicado 2017
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165por Vujasinovic, Miroslav, Valente, Roberto, Del Chiaro, Marco, Permert, Johan, Löhr, J.-Matthias“…This, in turn, contributes to malnutrition, specifically a lack of fat-soluble vitamins, antioxidants, and other micronutrients. Patients with pancreatic cancer and pancreatic exocrine insufficiency have, overall, an extremely poor prognosis with regard to surgical outcome and overall survival. …”
Publicado 2017
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166por Andersen, Dana K., Korc, Murray, Petersen, Gloria M., Eibl, Guido, Li, Donghui, Rickels, Michael R., Chari, Suresh T., Abbruzzese, James L.“…Longstanding type 2 diabetes (T2DM) is a risk factor for pancreatic cancer, but increasing epidemiological data point to PDAC as also a cause of diabetes due to unknown mechanisms. …”
Publicado 2017
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167“…Pancreatic cancer is an extremely dismal malignance. Chemotherapy has been widely applied to treat this intractable tumor. …”
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168“…Pancreatic cancer (PC) is the third leading cause of adult cancer mortality in the United States. …”
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169por Okui, Masayuki, Yamamichi, Takashi, Asakawa, Ayaka, Harada, Masahiko, Horio, Hirotoshi“…BACKGROUND: Pancreatic cancer is a highly aggressive solid tumor. Patients with metastases from pancreatic cancer have poor survival rates. …”
Publicado 2017
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170“…The accumulated risk of pancreatic cancer (PC) in LS patients is around 3.7% and developed tumors often present a characteristically medullary appearance with prominent lymphocytic infiltration. …”
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171“…The use of neoadjuvant therapies has played a major role for borderline resectable and locally advanced pancreatic cancers (PCs). For this group of patients, preoperative chemotherapy or chemoradiation has increased the likelihood of surgery with negative resection margins and overall survival. …”
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172“…This review summarizes the multiple functions accomplished by one major factor of pancreatic cancer cell stress response, the stress protein p8.…”
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173por Asai, Yasutsugu, Itoi, Takao, Sugimoto, Masahiro, Sofuni, Atsushi, Tsuchiya, Takayoshi, Tanaka, Reina, Tonozuka, Ryosuke, Honjo, Mitsuyoshi, Mukai, Shuntaro, Fujita, Mitsuru, Yamamoto, Kenjiro, Matsunami, Yukitoshi, Kurosawa, Takashi, Nagakawa, Yuichi, Kaneko, Miku, Ota, Sana, Kawachi, Shigeyuki, Shimazu, Motohide, Soga, Tomoyoshi, Tomita, Masaru, Sunamura, Makoto“…Detection of pancreatic cancer (PC) at a resectable stage is still difficult because of the lack of accurate detection tests. …”
Publicado 2018
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175“…Importantly, there has been limited success in the use of immunotherapy in the treatment of pancreatic cancer. Investigation into the complex tumor microenvironment of pancreatic cancer that is composed of immune cells, stromal cells, and extracellular matrix proteins has begun to shed light on important attributes of this microenvironment that act as barriers to the effective use of immunotherapy. …”
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176por Qi, Zi-Hao, Xu, Hua-Xiang, Zhang, Shi-Rong, Xu, Jin-Zhi, Li, Shuo, Gao, He-Li, Jin, Wei, Wang, Wen-Quan, Wu, Chun-Tao, Ni, Quan-Xing, Yu, Xian-Jun, Liu, Liang“…In this review, we focused on the latest discoveries and advancements of liquid biopsy technology in pancreatic cancer research and demonstrated how this technology is being used in clinical applications.…”
Publicado 2018
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177“…Moreover, CLDN18.2 is aberrantly expressed in malignancies of several other organs, such as pancreatic cancer (PC). A monoclonal antibody, zolbetuximab (formerly known as IMAB362), has been generated against CLDN18.2. …”
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178por Yeo, Charles J.Enlace del recurso
Publicado 2015
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