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1821“…BACKGROUND: Pancreatic cancer (PC) remains one of the most aggressive cancers worldwide. …”
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1822
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1823por Fujita, Mayumi, Somasundaram, Veena, Basudhar, Debashree, Cheng, Robert Y.S., Ridnour, Lisa A., Higuchi, Harumi, Imadome, Kaori, No, Jae Hong, Bharadwaj, Gaurav, Wink, David A.“…Pancreatic cancer is a highly metastatic tumor with an extremely low 5-year survival rate. …”
Publicado 2019
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1824por Yoo, Byunghee, Jordan, Veronica Clavijo, Sheedy, Patrick, Billig, Ann-Marie, Ross, Alana, Pantazopoulos, Pamela, Medarova, Zdravka“…However, the clinical results with these agents have demonstrated variability in the response. Pancreatic cancer, in particular, has proven resistant to initial immunotherapy approaches. …”
Publicado 2019
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1825“…In conclusion, ISOC1 exerts a role in pancreatic cancer cell growth and apoptosis, and may have a role in pancreatic cancer tumorigenesis.…”
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1826por Zhu, Xinxia, Burfeind, Kevin G., Michaelis, Katherine A., Braun, Theodore P., Olson, Brennan, Pelz, Katherine R., Morgan, Terry K., Marks, Daniel L.“…BACKGROUND: Up to 80% of pancreatic cancer patients suffer from cachexia, a devastating condition that exacerbates underlying disease, reduces quality of life, and increases treatment complications and mortality. …”
Publicado 2019
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1827por Hamada, Tsuyoshi, Yuan, Chen, Yurgelun, Matthew B., Perez, Kimberly, Khalaf, Natalia, Morales-Oyarvide, Vicente, Babic, Ana, Nowak, Jonathan A., Rubinson, Douglas A., Giannakis, Marios, Ng, Kimmie, Kraft, Peter, Stampfer, Meir J., Giovannucci, Edward L., Fuchs, Charles S., Ogino, Shuji, Wolpin, Brian M.“…BACKGROUND: Individuals with a family history of cancer may be at increased risk of pancreatic cancer. Ashkenazi Jewish (AJ) individuals carry increased risk for pancreatic cancer and other cancer types. …”
Publicado 2019
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1828
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1829
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1830“…However, the biological and molecular mechanisms of lncRNAs in pancreatic cancer are still unclear. Recent studies have reported that many lncRNAs are dysregulated in pancreatic cancer and closely associated with tumorigenesis, diagnosis and prognosis. …”
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1831por Adams, Christina R, Htwe, Htet Htwe, Marsh, Timothy, Wang, Aprilgate L, Montoya, Megan L, Subbaraj, Lakshmipriya, Tward, Aaron D, Bardeesy, Nabeel, Perera, Rushika MEnlace del recurso
Publicado 2019
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1832por Basile, Anna, De Marco, Margot, Festa, Michelina, Falco, Antonia, Iorio, Vittoria, Guerriero, Luana, Eletto, Daniela, Rea, Domenica, Arra, Claudio, Lamolinara, Alessia, Ballerini, Patrizia, Damiani, Verena, Rosati, Alessandra, Sala, Gianluca, Turco, Maria Caterina, Marzullo, Liberato, De Laurenzi, Vincenzo“…Furthermore, it specifically localizes into tumor tissues and significantly inhibits the growth of Mia PaCa‐2 pancreatic cancer cell xenografts. We propose BAG3‐H2L4 antibody as a potential clinical candidate for BAG3‐targeted therapy in pancreatic cancer.…”
Publicado 2019
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1833“…We examined the relationship of pancreatic ITGA3 expression with the clinical and pathological characteristics of patients with pancreatic cancer. Methods: Data mining was used to analyze pancreatic cancer data from The Cancer Genome Atlas database. …”
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1834“…Standard doses of conventionally fractionated radiation have had minimal to no impact on the survival duration of patients with locally advanced unresectable pancreatic cancer (LAPC). The use of low-dose stereotactic body radiation (SBRT) in 3- to 5-fractionshas thus far produced a modest improvement in median survival with minimal toxicity and shorter duration of treatment, but failed to produce a meaningful difference at 2 years and beyond. …”
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1835por Wallace, David R., Spandidos, Demetrios A., Tsatsakis, Aristidis, Schweitzer, Amie, Djordjevic, Vladimir, Djordjevic, Aleksandra Buha“…Pancreatic cancer (PC) is insidious with a high mortality rate due to the lack of symptomology prior to diagnosis. …”
Publicado 2019
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1836por Shi, Yu, Gao, Weina, Lytle, Nikki K., Huang, Peiwu, Yuan, Xiao, Dann, Amanda M., Ridinger-Saison, Maya, DelGiorno, Kathleen E., Antal, Corina E., Liang, Gaoyang, Atkins, Annette R., Erikson, Galina, Sun, Huaiyu, Meisenhelder, Jill, Terenziani, Elena, Woo, Gyunghwi, Fang, Linjing, Santisakultarm, Thom P., Manor, Uri, Xu, Ruilian, Becerra, Carlos R., Borazanci, Erkut, Von Hoff, Daniel D., Grandgenett, Paul M., Hollingsworth, Michael A., Leblanc, Mathias, Umetsu, Sarah E., Collisson, Eric A., Scadeng, Miriam, Lowy, Andrew M., Donahue, Timothy R., Reya, Tannishtha, Downes, Michael, Evans, Ronald M., Wahl, Geoffrey M., Pawson, Tony, Tian, Ruijun, Hunter, Tony“…The reciprocal interplay between PSCs and pancreatic cancer cells (PCCs) not only enhances tumour progression and metastasis but also sustains their own activation, facilitating a vicious cycle to exacerbate tumourigenesis and drug resistance(3–7). …”
Publicado 2019
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1837por Li, Hao, Zhang, Shi-Rong, Xu, Hua-Xiang, Wang, Wen-Quan, Li, Shuo, Li, Tian-Jiao, Ni, Quan-Xing, Yu, Xian-Jun, Liu, Liang, Wu, Chun-Tao“…Introduction: SRPX2 and RAB31 play important roles in tumorigenesis and metastasis; however, their prognostic value in pancreatic cancer remains unclear. This study aimed to investigate the potential interactions and effects of SRPX2 and RAB31 on the diagnosis and prognosis of pancreatic cancer. …”
Publicado 2019
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1838por Huang, Brian Z., Stram, Daniel O., Le Marchand, Loic, Haiman, Christopher A., Wilkens, Lynne R., Pandol, Stephen J., Zhang, Zuo‐Feng, Monroe, Kristine R., Setiawan, Veronica Wendy“…While disparity in pancreatic cancer incidence between blacks and whites has been observed, few studies have examined disparity in other ethnic minorities. …”
Publicado 2019
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1839“…BACKGROUND: This study aimed to use a network pharmacology approach to establish the effects of plumbagin on pancreatic cancer (PC) and to predict core targets and biological functions, pathways, and mechanisms of action. …”
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