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  1. 2021
    “…First, it linearizes c-di-AMP into pApA which is further hydrolyzed to 5′-AMP. MtbPDE is novel compared to c-di-AMP specific phosphodiesterase, YybT (or GdpP) in being a soluble protein and hydrolyzing c-di-AMP to 5′-AMP. …”
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    Two-Step Synthesis and Hydrolysis of Cyclic di-AMP in Mycobacterium tuberculosis
  2. 2022
    “…These different clinical entities include PAPA (pyogenic arthritis, pyoderma gangrenosum and acne conglobata), PASH (pyoderma gangrenosum, acne and suppurative hidradenitis), PAPASH (pyoderma gangrenosum, acne, suppurative hidradenitis and pyogenic arthritis), PsAPASH (pyoderma gangrenosum, acne, suppurative hidradenitis and psoriatic arthritis), PASS (pyoderma gangrenosum, acne conglobata, suppurative hidradenitis, and axial spondyloarthritis) and PAC (pyoderma gangrenosum, acne and ulcerative colitis), which can be distinguished by their clinical presentation and the presence or absence of mutations in several genes, such as the genes encoding proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1), nicastrin (NCSTN), Mediterranean fever (MEFV) and nucleotide-binding oligomerization domain-containing protein (NOD). …”
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    Ancient friends, revisited: Systematic review and case report of pyoderma gangrenosum-associated autoinflammatory syndromes
  3. 2023
    “…We organised a public-funded, multidisciplinary follow-up programme for COVID-19 patients discharged from the emergency department or from the inpatient wards of ‘Papa Giovanni XXIII’ Hospital, the largest public hospital in the area. …”
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    Surviving COVID-19 in Bergamo province: a post-acute outpatient re-evaluation
  4. 2024
    por Zhang, Lingchun, Li, Fenfen, Li, Xiaotian
    Publicado 2022
    “…The detection rates of the iron acquisition-associated genes ChuT and IutA were 77.3% (n = 17) and 50% (n = 11) and those of P fimbria papA and papC genes were 45% (n = 10) and 50% (n = 11), respectively. …”
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    Studies on Virulence and Extended-Spectrum β-Lactamase-Producing Uropathogenic Escherichia coli Isolates and Therapeutic Effect of Fosfomycin in Acute Pyelonephritis Mice
  5. 2025
    “…DisA synthesizes c-di-AMP from two molecules of ATP, whereas PdeA degrades c-di-AMP, as well as the linear degradation intermediate phosphoadenylyl-(3′→5′)-adenosine (pApA) to two molecules of AMP. Here, we show that a ydaO/kimA-type c-di-AMP-dependent riboswitch controls the expression of the strictly regulated cell wall peptidase gene nlpC in C. glutamicum. …”
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    C-di-AMP Is a Second Messenger in Corynebacterium glutamicum That Regulates Expression of a Cell Wall-Related Peptidase via a Riboswitch
  6. 2026
    por Alm, Erik, Broberg, Eeva K, Connor, Thomas, Hodcroft, Emma B, Komissarov, Andrey B, Maurer-Stroh, Sebastian, Melidou, Angeliki, Neher, Richard A, O’Toole, Áine, Pereyaslov, Dmitriy, Beerenwinkel, Niko, Posada-Céspedes, Susana, Jablonski, Kim Philipp, Ferreira, Pedro Falé, Topolsky, Ivan, Avšič-Županc, Tatjana, Korva, Miša, Poljak, Mario, Zakotnik, Samo, Zorec, Tomaž Mark, Bragstad, Karoline, Hungnes, Olav, Stene-Johansen, Kathrine, Reusken, Chantal, Meijer, Adam, Vennema, Harry, Ruiz-Roldán, Lidia, Bracho, María Alma, García-González, Neris, Chiner-Oms, Álvaro, Cancino-Muñoz, Irving, Comas, Iñaki, Goig, Galo A, Torres-Puente, Manuela, López, Mariana G, Martínez-Priego, Llúcia, D'Auria, Giuseppe, Ferrús-Abad, Loreto, de Marco, Griselda, Galan-Vendrell, Inmaculada, Carbó-Ramirez, Sandra, Ruíz-Hueso, Paula, Coscollá, Mireia, Polackova, Katerina, Kramna, Lenka, Cinek, Ondrej, Richter, Jan, Krashias, George, Tryfonos, Christina, Bashiardes, Stavros, Koptides, Dana, Christodoulou, Christina, Bartolini, Barbara, Gruber, Cesare Em, Di Caro, Antonino, Castilletti, Concetta, Stefani, Fabrizio, Rimoldi, Sara Giordana, Romeri, Francesca, Salerno, Franco, Polesello, Stefano, Nagy, Alexander, Jirincova, Helena, Vecerova, Jaromira, Novakova, Ludmila, Cordey, Samuel, Murtskhvaladze, Marine, Kotaria, Nato, Schär, Tobias, Beisel, Christian, Vugrek, Oliver, Rokić, Filip, Trgovec-Greif, Lovro, Jurak, Igor, Rukavina, Tomislav, Sučić, Neven, Schønning, Kristian, Karst, Søren M, Kirkegaard, Rasmus H, Michaelsen, Thomas Y, Sørensen, Emil Aa, Knutson, Simon, Brandt, Jakob, Le-Quy, Vang, Sørensen, Trine, Petersen, Celine, Pedersen, Martin Schou, Larsen, Sanne Løkkegaard, Skov, Marianne Nielsine, Rasmussen, Morten, Fonager, Jannik, Fomsgaard, Anders, Maksyutov, Rinat Amirovich, Gavrilova, Elena Vasil'Evna, Pyankov, Oleg Victorovich, Bodnev, Sergey Alexandrovich, Tregubchak, Tatyana Vladimirovna, Shvalov, Alexander Nikolayevich, Antonets, Denis Victorovich, Resende, Paola Cristina, Goya, Stephanie, Perrin, Amandine, Lee, Raphael Tc, Yadahalli, Shilpa, Han, Alvin X, Russell, Colin A, Schmutz, Stefan, Zaheri, Maryam, Kufner, Verena, Huber, Michael, Trkola, Alexandra, Antwerpen, Markus, Walter, Mathias C, van der Werf, Sylvie, Gambaro, Fabiana, Behillil, Sylvie, Enouf, Vincent, Donati, Flora, Ustinova, Monta, Rovite, Vita, Klovins, Janis, Savicka, Oksana, Wienecke-Baldacchino, Anke K, Ragimbeau, Catherine, Fournier, Guillaume, Mossong, Joël, Aberle, Stephan W, Haukland, Mattias, Enkirch, Theresa, Advani, Abdolreza, Karlberg, Maria Lind, Lindsjö, Oskar Karlsson, Broddesson, Sandra, Sláviková, Monika, Ličková, Martina, Klempa, Boris, Staroňová, Edita, Tichá, Elena, Szemes, Tomáš, Rusňáková, Diana, Stadler, Tanja, Quer, Josep, Anton, Andres, Andres, Cristina, Piñana, Maria, Garcia-Cehic, Damir, Pumarola, Tomas, Izopet, Jacques, Gioula, Georgia, Exindari, Maria, Papa, Anna, Chatzidimitriou, Dimitrios, Metallidis, Symeon, Pappa, Stella, Macek Jr, Milan, Geryk, Jan, Brož, Petr, Briksí, Aleš, Hubáček, Petr, Dřevínek, Pavel, Zajac, Miroslav, Kvapil, Petr, Holub, Michal, Kvapilová, Kateřina, Novotný, Adam, Kašný, Martin, Klempt, Petr, Vapalahti, Olli, Smura, Teemu, Sironen, Tarja, Selhorst, Philippe, Anthony, Colin, Ariën, Kevin, Simon-Loriere, Etienne, Rabalski, Lukasz, Bienkowska-Szewczyk, Krystyna, Borges, Vítor, Isidro, Joana, Gomes, João Paulo, Guiomar, Raquel, Pechirra, Pedro, Costa, Inês, Duarte, Sílvia, Vieira, Luís, Pyrc, Krzysztof, Zuckerman, Neta S, Turdikulova, Shahlo, Abdullaev, Alisher, Dalimova, Dilbar, Abdurakhimov, Abror, Tagliabracci, Adriano, Alessandrini, Federica, Melchionda, Filomena, Onofri, Valerio, Turchi, Chiara, Bagnarelli, Patrizia, Menzo, Stefano, Caucci, Sara, Di Sante, Laura, Popa, Alexandra, Genger, Jakob-Wendelin, Agerer, Benedikt, Lercher, Alexander, Endler, Lukas, Smyth, Mark, Penz, Thomas, Schuster, Michael, Senekowitsch, Martin, Laine, Jan, Bock, Christoph, Bergthaler, Andreas, Shevtsov, Alexandr, Kalendar, Ruslan, Ramanculov, Yerlan, Graf, Alexander, Muenchhoff, Maximilian, Keppler, Oliver T, Krebs, Stefan, Blum, Helmut, Marcello, Alessandro, Licastro, Danilo, D'Agaro, Pierlanfranco, Laubscher, Florian, Vidanovic, Dejan, Tesovic, Bojana, Volkening, Jeremy, Clementi, Nicola, Mancini, Nicasio, Rupnik, Maja, Mahnic, Aleksander, Walker, Andreas, Houwaart, Torsten, Wienemann, Tobias, Vasconcelos, Malte Kohns, Strelow, Daniel, Jensen, Björn-Erik Ole, Senff, Tina, Hülse, Lisanna, Adams, Ortwin, Andree, Marcel, Hauka, Sandra, Feldt, Torsten, Keitel, Verena, Kindgen-Milles, Detlef, Timm, Jörg, Pfeffer, Klaus, Dilthey, Alexander T, Moore, Catherine, Ozdarendeli, Aykut, Pavel, Shaikh Terkis Islam, Yetiskin, Hazel, Aydin, Gunsu, Holyavkin, Can, Uygut, Muhammet Ali, Cevik, Ceren, Shchetinin, Alexey, Gushchin, Vladimir, Dinler-Doganay, Gizem, Doganay, Levent, Kizilboga-Akgun, Tugba, Karacan, Ilker, Pancer, Katarzyna, Maes, Piet, Martí-Carreras, Joan, Wawina-Bokalanga, Tony, Vanmechelen, Bert, Thürmer, Andrea, Wedde, Marianne, Dürrwald, Ralf, Von Kleist, Max, Drechsel, Oliver, Wolff, Thorsten, Fuchs, Stephan, Kmiecinski, Rene, Michel, Janine, Nitsche, Andreas, Casas, Inmaculada, Caballero, María Iglesias, Zaballos, Ángel, Jiménez, Pilar, Jiménez, Mercedes, Fernández, Sara Monzón, Fernández, Sarai Varona, De La Plaza, Isabel Cuesta, Fadeev, Artem, Ivanova, Anna, Sergeeva, Mariia, Stefanelli, Paola, Torok, M Estee, Hall, Grant, da Silva Filipe, Ana, Turtle, Lance, Afifi, Safiah, Mccluggage, Kathryn, Beer, Robert, Ledesma, Juan, Maksimovic, Joshua, Spellman, Karla, Hamilton, William L, Marchbank, Angela, Southgate, Joel Alexander, Underwood, Anthony, Taylor, Ben, Yeats, Corin, Abudahab, Khalil, Gemmell, Matthew R, Eccles, Richard, Lucaci, Anita, Nelson, Charlotte Abigail, Rainbow, Lucille, Whitehead, Mark, Gregory, Richard, Haldenby, Sam, Paterson, Steve, Hughes, Margaret A, Curran, Martin D, Baker, David, Tucker, Rachel, Green, Luke R, Feltwell, Theresa, Halstead, Fenella D, Wyles, Matthew, Jahun, Aminu S, Ahmad, Shazaad S Y, Georgana, Iliana, Goodfellow, Ian, Yakovleva, Anna, Meredith, Luke W, Gavriil, Artemis, Awan, Ali Raza, Fisher, Chloe, Edgeworth, Jonathan, Lynch, Jessica, Moore, Nathan, Williams, Rebecca, Kidd, Stephen P, Cortes, Nicholas, Brunker, Kirstyn, Mccrone, John T, Quick, Joshua, Duckworth, Nichola, Walsh, Sarah, Sloan, Tim, Ludden, Catherine, George, Ryan P, Eltringham, Gary, Brown, Julianne R, Aranday-Cortes, Elihu, Shepherd, James G, Hughes, Joseph, Li, Kathy K, Williams, Thomas C, Johnson, Natasha, Jesudason, Natasha, Mair, Daniel, Thomson, Emma, Shah, Rajiv, Parr, Yasmin A, Carmichael, Stephen, Robertson, David L, Nomikou, Kyriaki, Broos, Alice, Niebel, Marc, Smollett, Katherine, Tong, Lily, Miah, Shahjahan, Wittner, Anita, Phillips, Nicole, Payne, Brendan, Dewar, Rebecca, Holmes, Alison, Bolt, Frances, Price, James R, Mookerjee, Siddharth, Sethi, Dheeraj K, Potter, Will, Stanley, Rachael, Prakash, Reenesh, Dervisevic, Samir, Graham, Jonathan Clive, Nelson, Andrew, Smith, Darren, Young, Gregory R, Yew, Wen Chyin, Todd, John A, Trebes, Amy, Andersson, Monique, Bull, Matthew, Watkins, Joanne, Birchley, Alec, Gatica-Wilcox, Bree, Gilbert, Lauren, Kumžiene-Summerhayes, Sara, Rey, Sara, Chauhan, Anoop, Butcher, Ethan, Bicknell, Kelly, Elliott, Scott, Glaysher, Sharon, Lackenby, Angie, Bibby, David, Platt, Steven, Mohamed, Hodan, Machin, Nicholas William, Mbisa, Jean Lutamyo, Evans, Jonathan, Perry, Malorie, Pacchiarini, Nicole, Corden, Sally, Adams, Alexander Geraint, Gaskin, Amy, Coombs, Jason, Graham, Lee John, Cottrell, Simon, Morgan, Mari, Gifford, Laura, Kolyva, Anastasia, Rudder, Steven John, Trotter, Alexander J, Mather, Alison E, Aydin, Alp, Page, Andrew J, Kay, Gemma L, de Oliveira Martins, Leonardo, Yasir, Muhammad, Alikhan, Nabil-Fareed, Thomson, Nicholas M, Gilroy, Rachel, Kingsley, Robert A, O'Grady, Justin, Gutierrez, Ana Victoria, Diaz, Maria, Le Viet, Thanh, Tedim, Ana P, Adriaenssens, Evelien M, Mcclure, C Patrick, Moore, Christopher, Sang, Fei, Clark, Gemma, Howson-Wells, Hannah C, Debebe, Johnny, Ball, Jonathan, Chappell, Joseph, Khakh, Manjinder, Carlile, Matthew, Loose, Matthew, Lister, Michelle M, Holmes, Nadine, Tsoleridis, Theocharis, Fleming, Vicki M, Wright, Victoria, Smith, Wendy, Gallagher, Michael D, Parker, Matthew, Partridge, David G, Evans, Cariad, Baker, Paul, Essex, Sarah, Liggett, Steven, Keeley, Alexander J, Bashton, Matthew, Rooke, Stefan, Dervisevic, Samir, Meader, Emma Jane, Balcazar Lopez, Carlos Enrique, Angyal, Adrienn, Kristiansen, Mark, Tutill, Helena J, Findlay, Jacqueline, Mestek-Boukhibar, Lamia, Forrest, Leysa, Dyal, Patricia, Williams, Rachel J, Panchbhaya, Yasmin, Williams, Charlotte A, Roy, Sunando, Pandey, Sarojini, Stockton, Jo, Loman, Nicholas J, Poplawski, Radoslaw, Nicholls, Samuel, Rowe, W P M, Khokhar, Fahad, Pinckert, Malte Lars, Hosmillo, Myra, Chaudhry, Yasmin, Caller, Laura G, Davidson, Rose K, Griffith, Luke, Rambaut, Andrew, Jackson, Ben, Colquhoun, Rachel, Hill, Verity, Nichols, Jenna, Asamaphan, Patawee, Darby, Alistair, Jackson, Kathryn A, Iturriza-Gomara, Miren, Vamos, Ecaterina Edith, Green, Angie, Aanensen, David, Bonsall, David, Buck, David, Macintyre-Cockett, George, de Cesare, Mariateresa, Pybus, Oliver, Golubchik, Tanya, Scarlett, Garry, Loveson, Katie F, Robson, Samuel C, Beckett, Angela, Lindsey, Benjamin, Groves, Danielle C, Parsons, Paul J, Mchugh, Martin P, Barnes, James Daniel, Manso, Carmen F, Grammatopoulos, Dimitris, Menger, Katja Elisabeth, Harrison, Ewan, Gunson, Rory, Peacock, Sharon J, Gonzalez, Gabriel, Carr, Michael, Mihaela, Lazar, Popovici, Odette, Brytting, Mia, Bresner, Catherine, Fuller, William, Workman, Trudy, Mentis, Andreas F, Kossyvakis, Athanasios, Karamitros, Timokratis, Pogka, Vasiliki, Kalliaropoulos, Antonios, Horefti, Elina, Kontou, Aspasia, Martinez-Gonzalez, Beatriz, Labropoulou, Voula, Voulgari-Kokota, Androniki, Evangelidou, Maria, Bizta, Panagiota, Belimezi, Maria, Lambrechts, Laurens, Doymaz, Mehmet Z, Yazici, Merve Kalkan, Cetin, Nesibe S, Karaaslan, Elif, Kallio-Kokko, Hannimari, Virtanen, Jenni, Suvanto, Maija, Nguyen, Phuoc Truong, Ellonen, Pekka, Hannula, Sari, Kangas, Harri, Sreenu, Vattipally B, Burián, Katalin, Terhes, Gabriella, Gombos, Katalin, Gyenesei, Attila, Urbán, Péter, Herczeg, Róbert, Jakab, Ferenc, Kemenesi, Gábor, Tóth, Gábor Endre, Somogyi, Balázs, Zana, Brigitta, Zeghbib, Safia, Kuczmog, Anett, Földes, Fanni, Lanszki, Zsófia, Madai, Mónika, Papp, Henrietta, Nagy, Ágnes, Pereszlényi, Csaba István, Babinszky, Gergely Csaba, Dudás, Gábor, Csoma, Eszter, Abou Tayoun, Ahmad N, Alsheikh-Ali, Alawi A, Loney, Tom, Nowotny, Norbert, Abdul-Wahab, Osama, Gonzalez-Candelas, Fernando, Andersen, Martin H, Taylor, Sarah
    Publicado 2020
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    Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020
  7. 2027
    Video
    El abrazo partido
  8. 2028
    “…To develop a specific diagnostic test, we analyzed leukocyte gene expression profiles of 44 pediatric SoJIA patients, 94 pediatric patients with acute viral and bacterial infections, 38 pediatric patients with systemic lupus erythematosus (SLE), 6 patients with PAPA syndrome, and 39 healthy children. Statistical group comparison and class prediction identified genes differentially expressed in SoJIA patients compared with healthy children. …”
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    Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade
  9. 2029
    “…Among the potential substrates tested, DacA was able to utilize both ATP and ADP, but not AMP, pApA, c-di-AMP or GTP. By using gel filtration and analytical ultracentrifugation, we further demonstrated that DacA existed as an octamer, with the N-terminal domain contributing to tetramerization and the C-terminal domain providing additional dimerization. …”
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    Mycobacterium tuberculosis Rv3586 (DacA) Is a Diadenylate Cyclase That Converts ATP or ADP into c-di-AMP
  10. 2030
    “…In contrast, inhibition of platelet aggregation by NO donors was more potent with a fast NO releaser (DEA-NO, t (½) = 2 min) than slow NO releasers such as PAPA-NO (t (½) = 15 min) or other slow NO donors. …”
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    Inhibition of platelet aggregation by carbon monoxide-releasing molecules (CO-RMs): comparison with NO donors
  11. 2031
    “…Using a panel of techniques (UV, both steady state fluorescence and fluorescence lifetime measurements, circular dichroism (CD), NMR, and Job plots), we demonstrate that c-di-AMP, which contains only two adenine bases is an exception to this rule and that it can form complexes with coralyne, even at low micromolar concentrations. Interestingly, pApA (the linear analog of c-di-AMP that also contains two adenines) or cyclic diguanylate (c-di-GMP, another nucleotide second messenger in bacteria) did not form any complex with coralyne. …”
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    Unexpected Complex Formation between Coralyne and Cyclic Diadenosine Monophosphate Providing a Simple Fluorescent Turn-on Assay to Detect This Bacterial Second Messenger
  12. 2032
    “…In the analysis of fimH, papA, papC, iutA, ireA and fyuA genes, the highest frequency was observed in these two phylogroups. …”
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    Determination of virulence determinants of Escherichia coli strains isolated from patients with colorectal cancer compared to the healthy subjects
  13. 2033
    “…METHODS: Multicenter prospective observational study on adult patients with blunt splenic trauma managed between 2014 and 2016 in two Italian trauma centers (ASST Papa Giovanni XXIII in Bergamo and Sant’Anna University Hospital in Ferrara). …”
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    The World Society of Emergency Surgery (WSES) spleen trauma classification: a useful tool in the management of splenic trauma
  14. 2034
    “…The B2 phylogroup was over-represented (79.6%) and positively associated with the presence of numerous virulence factors (VFs), including those defining the extra-intestinal pathogenic E. coli isolates (presence of ≥2 VFs: papA, sfaS, focG, afaD, iutA, and kpsMTII) and those more specifically related to uropathogenic E. coli (cnf1, hlyD). …”
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    Pathogenic Escherichia coli in Dogs Reveals the Predominance of ST372 and the Human-Associated ST73 Extra-Intestinal Lineages
  15. 2035
    “…The province of Bergamo in Italy and in particular Papa Giovanni XXIII Hospital was one of the first areas to be hit by the SARS-CoV-2 outbreak and experience firsthand all the different phases of the crisis. …”
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    A Snapshot from the Department of Urology in Bergamo Evaluating the Timeline of the SARS-CoV-2 Outbreak: Which Patients Are We Missing?
  16. 2036
    por Cretti, Fabiola
    Publicado 2018
    “…INTRODUCTION: In light of both current Italian radioprotection law and the new European Directive, radiation dose monitoring was carried out on the interventional staff, of the new Papa Giovanni XXIII Hospital in Bergamo, Italy, potentially exposed to high radiation levels. …”
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    Assessment of occupational radiation dose in interventional settings
  17. 2037
    “…Conclusion: Herein, we report a novel variant in GLI1 gene, causing autosomal recessive post-axial polydactyly type A (PAPA) type 8. This confirms the critical role of GLI1 in digit development and might help in genotype–phenotype correlation in the future.…”
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    A Novel Homozygous Missense Mutation in the Zinc Finger DNA Binding Domain of GLI1 Causes Recessive Post-Axial Polydactyly
  18. 2038
    “…Mutations in the adaptor protein PSTPIP1 cause a spectrum of autoinflammatory diseases, including PAPA and PAMI; however, the mechanism underlying these diseases remains unknown. …”
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    PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders
  19. 2039
    por Genet, François, 1640-1702
    Publicado 1775
    Tabla de Contenidos: “…"Continens Tractatus de quinto, reliquis decalogi praeceptis; Epistolam Pastoralem Clementis Papae XI. iu ssuad Episcopos Scriptam: Resolutiones in materia Usurae, Edictum Romanum pro observatione Quadragesime; itemque tres Benedicti XIV. unam Clementis XIII. …”
    Libro
    Theologia moralis juxta sacrae scripturae. Canonum et ss. patrum mentem, Juffu Eminentifs. ac Reverendifs. Stephani Cardinalis Le camus Episcopi Gratianopolitani, Gallica lingua, & deinde Latina exarata. Tomus septimus.
  20. 2040
    Publicado 1994
    CD Audiom
    French chansons
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