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  1. 3881
    “…This article intends to present the practical approach of the concepts and guidelines illustrated in the routine aesthetic diagnosis, the anatomical changes in the various tissue layers that are externally appreciated, but detailing them under a regional approach (upper, middle, and lower thirds). Our paradigm seeks that as professionals of aesthetic and regenerative medicine we identify facial aging not only as the obvious wrinkles and other changes in the skin, but that we diagnose according to the proposed parameters, so that when considering the rejuvenation treatment, we identify which are facial tissues that have changed due to aging and must therefore be restored to harmonize the face according to the ideal forms and proportions that must prevail (morphometry).…”
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  2. 3882
  3. 3883
    “…Subsequently, the publication of the results of the main clinical trials showing a decrease in the progression of pulmonary emphysema has led to a debate over a possible change in the main objective of treatment, from biochemical efficacy to clinical efficacy in terms of lung densitometry deterioration prevention. This new paradigm has produced a series controversies and unanswered questions which face clinicians managing AAT deficiency. …”
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  4. 3884
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  6. 3886
    “…Methods: Employing a hybrid artificial intelligence (AI) paradigm that combines traditional rule-based morphological manipulations with modern statistical machine learning, we deployed a next generation software, ALICE (Automated Liquid Biopsy Cell Enumerator) to identify and enumerate minute amounts of tumor cell phenotypes bestrewed in massive populations of leukocytes. …”
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  7. 3887
    “…In the well-established psychological refractory period (PRP) paradigm, tasks are triggered by two stimuli with a short temporal delay (stimulus onset asynchrony; SOA), thereby allowing control of the degree of task overlap. …”
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  8. 3888
    “…In this work, we demonstrate an electrically pumped quantum dot (QD) random laser with visible emission based on a previously unexplored paradigm named coherent Förster resonance energy transfer (CFRET). …”
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  11. 3891
    “…With the advent of novel oral anticoagulants (NOAC's) with preserved efficacy and attenuated bleeding rates, anticoagulation in AF is undergoing paradigm shift. The spotlight is now shifting from conventional triple therapy (vitamin-K antagonist + dual antiplatelet therapy [VKA + DAPT]) to novel dual therapy (NOAC + single antiplatelet therapy [SAPT]) in situation of anticoagulated AF patients undergoing PCI. …”
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  12. 3892
    “…Using a novel aggression paradigm, we sought to explore the influence of approach‐motivated anger on neural responses to feedback indicating the opportunity to seek revenge against an offending opponent by examining the reward positivity (RewP), an event‐related potential indexing performance feedback. …”
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  14. 3894
    “…In the present study, based on a social approach paradigm using a single‐chamber apparatus, we have developed two reproducible and simple social approach tests, SAT1 and SAT2, in ICR mice. …”
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  15. 3895
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  20. 3900
    “…CONCLUSION: This regenerative cell therapy study using MSCs shows efficacy toward a low dose, which changes the paradigm that more cells lead to better wound healing outcome. …”
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