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  1. 40021
    “…Despite its success as a longevity treatment in mice, higher doses and longer delivery paradigms for rapamycin may lead to a disconnect between life span and beneficial health outcomes.…”
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    Age‐related changes to adipose tissue and peripheral neuropathy in genetically diverse HET3 mice differ by sex and are not mitigated by rapamycin longevity treatment
  2. 40022
    “…CONCLUSIONS: Under the current submaximal angioplasty and/or stenting treatment paradigms, remodeling patterns may not influence the outcome of ischemic events and NICLs. …”
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    Patterns and implications of artery remodeling based on high-resolution vessel wall imaging in symptomatic severe basilar artery stenosis
  3. 40023
    “…To date, there is limited research integrating different paradigms to provide a cohesive view of the mechanisms and processes involved in preschool children’s word learning. …”
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    Understanding preschoolers’ word learning success in different scenarios: disambiguation meets statistical learning and eBook reading
  4. 40024
    “…A better understanding of OC biology could provide more effective therapeutic paradigms for different OC subtypes. METHODS: To reveal the heterogeneity of T cell-associated subclusters in OC, we performed an in-depth analysis of single-cell transcriptional profiles and clinical information of patients with OC. …”
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    Ovarian cancer-associated immune exhaustion involves SPP1+ T cell and NKT cell, symbolizing more malignant progression
  5. 40025
    “…Second, while the social environment is dynamic (i.e., our behaviors and reactions influence those of our social partners and vice-versa), the bulk of IL research employed noninteractive paradigms. Using a novel task, we examine whether IL is involved in the acquisition of regularities from a dynamic interaction with a realistic real-life-like agent. …”
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    Implicit and explicit learning of socio-emotional information in a dynamic interaction with a virtual avatar
  6. 40026
    “…Conclusion: EDL showed superior performance to TL systems for both (a) unbalanced and unaugmented and (b) balanced and augmented datasets for both (i) seen and (ii) unseen paradigms, validating both our hypotheses.…”
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    Ensemble Deep Learning Derived from Transfer Learning for Classification of COVID-19 Patients on Hybrid Deep-Learning-Based Lung Segmentation: A Data Augmentation and Balancing Framework
  7. 40027
    “…Infants completed standardized stress paradigms at one month and six months. There were several key findings. …”
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    Online Artículo Texto
    Maternal Early Life Adversity and Infant Stress Regulation: Intergenerational Associations and Mediation by Maternal Prenatal Mental Health
  8. 40028
    “…The software and virtual environment were mostly developed based on vision therapy and dichoptic training paradigms. CONCLUSION: It has been suggested that virtual reality technology offers a potentially effective tool for amblyopia, strabismus, and myopia studies. …”
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    Design and assessment of amblyopia, strabismus, and myopia treatment and vision training using virtual reality
  9. 40029
    “…Furthermore, integration of medical tr.AI.ning into the medical curriculum will enable long-term and large-scale detection of benefits and limitations of this approach, providing enhanced alternative teaching paradigms for VR technology.…”
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    Immersive training of clinical decision making with AI driven virtual patients – a new VR platform called medical tr.AI.ning
  10. 40030
    por Mulla, Daanish M., Keir, Peter J.
    Publicado 2023
    “…The combined efforts across the many disciplines aimed at understanding human movement has resulted in a rich and rapidly growing body of literature overflowing with theories, models, and experimental paradigms. As a result, gathering knowledge and drawing connections between the overlapping but seemingly disparate fields can be an overwhelming endeavour. …”
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    Neuromuscular control: from a biomechanist's perspective
  11. 40031
    “…This study hypothesizes that EBPRs may disagree about intervention ratings because they either use different rating paradigms or they use different studies as evidence of intervention effectiveness (or both). …”
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    Discrepancies in Ratings of Behavioral Healthcare Interventions Among Evidence-Based Program Resources Websites
  12. 40032
    “…RESULTS: We demonstrate that there is no performance loss when testing the proposed method against separately trained networks. Of the training paradigms investigated, the fully adversarial CycleGAN performs the worst, while the fully supervised U-Net generates more realistic voxel intensities and performed better than Pix2Pix in generating contrast images for use in a downstream segmentation task. …”
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    Multi-phase synthetic contrast enhancement in interventional computed tomography for guiding renal cryotherapy
  13. 40033
    “…In our initial round of screening, we employed the two-bottle-choice paradigms to assess alcohol, methamphetamine, and nicotine intake. …”
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    DISCOVERY AND VALIDATION OF GENES DRIVING DRUG-INTAKE AND RELATED BEHAVIORAL TRAITS IN MICE
  14. 40034
    “…In iMSN-TRAP-Drd2HET mice, increased Cartpt and reduced S100a10 (p11) expression recapitulated previous observations in cocaine paradigms. Electrophysiology experiments supported a higher GABA tone in iMSN-Drd2HET mice. …”
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    Low Dopamine D2 Receptor Expression Drives Gene Networks Related to GABA, cAMP, Growth and Neuroinflammation in Striatal Indirect Pathway Neurons
  15. 40035
    “…We also recapitulate a previously reported genetic interaction and show that Mvp(+/−);Mapk3(+/−) mice exhibit behavioral deficits, notably decreased anxiety-like traits detected in the elevated plus maze and open field paradigms. CONCLUSIONS: Our study highlights multiple gene drivers in neuroanatomical phenotypes, interacting with each other through complex relationships. …”
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    Dissecting the autism-associated 16p11.2 locus identifies multiple drivers in neuroanatomical phenotypes and unveils a male-specific role for the major vault protein
  16. 40036
    “…Studies evaluating and comparing TDCS to these structures have provided conflicting results, however, likely due to varying paradigms and stimulation parameters. Here we applied TDCS to CB and M1 within the same experimental design, to enable direct comparison of their roles in motor sequence learning. …”
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    Suppression of Motor Sequence Learning and Execution Through Anodal Cerebellar Transcranial Electrical Stimulation
  17. 40037
    “…The review uncovered different paradigms of LMIC to HIC innovation transfer and exchange, including unidirectional transfers from LMICs to HICs as well as bidirectional or multidirectional mutually beneficial exchanges. …”
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    Reversing the trend: a scoping review of health innovation transfer or exchange from low- and middle-income countries to high-income countries
  18. 40038
    “…INTRODUCTION: Chronic gastroduodenal symptoms are frequently overlapping within existing diagnostic paradigms, and current diagnostic tests are insensitive to underlying pathophysiologies. …”
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    Gastric Alimetry in the Management of Chronic Gastroduodenal Disorders: Impact to Diagnosis and Health Care Utilization
  19. 40039
    “…The proposed method, finding clear differences between bursting behavior in high and low beta bands, has clearly demonstrated the importance of considering wide frequency bands for beta burst behavior with implications for closed-loop DBS paradigms. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13311-023-01447-4.…”
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    Wavelet-Based Bracketing, Time–Frequency Beta Burst Detection: New Insights in Parkinson’s Disease
  20. 40040
    “…CONCLUSIONS: Taken together, the findings are of sufficient significance to warrant further studies to evaluate the systemic effects of SWCNT under workplace or environmental exposure paradigms.…”
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    Cardiovascular Effects of Pulmonary Exposure to Single-Wall Carbon Nanotubes
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