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  1. 40061
    “…BACKGROUND: There appears to be an inconsistency in experimental paradigms used in fMRI research on moral judgments. …”
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    Neural correlates of moral judgments in first- and third-person perspectives: implications for neuroethics and beyond
  2. 40062
    “…The majority of pre-clinical studies of hypoxic-ischemic encephalopathy at term-equivalent have focused on either relatively mild insults, or on functional paradigms of cerebral ischemia or hypoxia-ischemia/hypotension. …”
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    Status Epilepticus after Prolonged Umbilical Cord Occlusion Is Associated with Greater Neural Injury Fetal Sheep at Term-Equivalent
  3. 40063
    “…Although lower-order repetitive behaviors are measured in mouse models in several paradigms, so far there have been no high-throughput tests directly measuring cognitive rigidity. …”
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    A novel automated behavioral test battery assessing cognitive rigidity in two genetic mouse models of autism
  4. 40064
    “…The other 3 were performed as part of treatment paradigms for giant middle cerebral artery aneurysms. …”
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    Internal Maxillary Artery-Middle Cerebral Artery Bypass: Infratemporal Approach for Subcranial-Intracranial (SC-IC) Bypass
  5. 40065
    “…However, this elemental-contextual categorization scheme has only been tested in limited behavioral paradigms and it is largely unknown whether it can be generalized across different learning situations. …”
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    Elemental or contextual? It depends: individual difference in the hippocampal dependence of associative learning for a simple sensory stimulus
  6. 40066
    “…Importantly, F1-LPD mice are protected against high-fat-diet-induced obesity. Clearly, different paradigms of exposure to malnutrition may be associated with differences in energy expenditure, food intake, weight and different susceptibilities to various symptoms associated with metabolic syndrome. …”
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    Perinatal Protein Malnutrition Affects Mitochondrial Function in Adult and Results in a Resistance to High Fat Diet-Induced Obesity
  7. 40067
    “…The patient was scanned in a 1.5-T magnetic resonance scanner, prior to and after the 10-week VGT/CBT combined treatment, using two paradigms: (1) an emotional face-matching task, and (2) a multi-source interference task (MSIT). …”
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    Physiological and Brain Activity After a Combined Cognitive Behavioral Treatment Plus Video Game Therapy for Emotional Regulation in Bulimia Nervosa: A Case Report
  8. 40068
    “…These effects are related to the concept of metaplasticity. Behavioral paradigms are described that induce metaplastic effects within the spinal cord. …”
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    Metaplasticity and behavior: how training and inflammation affect plastic potential within the spinal cord and recovery after injury
  9. 40069
    “…Results from functional brain imaging studies investigating the neural profile of AN using cognitive and emotional task paradigms are difficult to reconcile. Task-related imaging studies often require a high level of compliance and can only partially explore the distributed nature and complexity of brain function. …”
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    Increased resting state functional connectivity in the fronto-parietal and default mode network in anorexia nervosa
  10. 40070
    “…Recent work has found that behaviorally inhibited (BI) individuals acquire conditioned eyeblinks faster than non-inhibited (NI) individuals in omission and yoked paradigms in which the predictive relationship between the conditioned stimulus (CS) and unconditional stimulus (US) is less than optimal as compared to standard training with CS-US paired trials (Holloway et al., 2014). …”
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    Avoidance prone individuals self reporting behavioral inhibition exhibit facilitated acquisition and altered extinction of conditioned eyeblinks with partial reinforcement schedules
  11. 40071
    “…METHODS: We studied the expression of HIP/PAP and two of its putative effectors, cAMP-regulated phosphoprotein 19 (ARPP19) and growth-associated protein 43 (GAP-43), in the neonatal brain, and the protective/regenerative properties of HIP/PAP in three paradigms of perinatal excitotoxicity: intracerebral injection of the NMDA agonist ibotenate in newborn pups, a pediatric model of traumatic brain injury, and cultured primary cortical neurons. …”
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    HIP/PAP prevents excitotoxic neuronal death and promotes plasticity
  12. 40072
    “…Urbahns, head of global discovery technologies at Merck research laboratories, gave insights from research practice in the pharmaceutical industry and introduced a shift in the view on present-day drug discovery paradigms.…”
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    Report on the 6th scientific meeting of the “Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie” (NEUROWIND e.V.) held in Motzen, Germany, Oct. 31th – Nov. 2nd, 2014
  13. 40073
    “…Compounds enhancing neuronal insulin receptor-mediated transmission exert an antidepressant-like effect in several pre-clinical paradigms of depression; similarly, such properties for DS were found with a stress-induced anhedonia model. …”
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    Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression
  14. 40074
    “…Tasks involving social recognition and olfactory conditioning paradigms showed that old nNOS(−/−) animals had improved retention of learning compared to similar aged wildtype controls. …”
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    Aged neuronal nitric oxide knockout mice show preserved olfactory learning in both social recognition and odor-conditioning tasks
  15. 40075
    “…Results revealed long-term body weight gain alterations in the growing rats and sex-specific impairments in spatial (female) and recognition (male) learning and memory paradigms. A markedly decreased expression of hippocampal NMDA receptor GluN1 subunit in female- and increased expression of AMPA GluR1 subunit protein expression in male rats were also found. …”
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    Repeated Neonatal Propofol Administration Induces Sex-Dependent Long-Term Impairments on Spatial and Recognition Memory in Rats
  16. 40076
    “…Integration of elotuzumab into multidrug therapeutic paradigms seems logical, as elotuzumab is more effective when combined with other agents, such as immunomodulatory drugs or proteasome inhibitors. …”
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    Profile of elotuzumab and its potential in the treatment of multiple myeloma
  17. 40077
    “…Social stressors that rely on the inclusion of confederates (i.e., Trier Social Stress Test, TSST) are often used in clinical laboratory research paradigms to elicit a measurable stress response in participants. …”
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    Stress reactivity to an electronic version of the Trier Social Stress Test: a pilot study
  18. 40078
    “…Our results demonstrated that long-term administration of memantine induces anxiety-like behavior in mice in the light–dark box and elevated plus-maze paradigms. Additionally, the administration of memantine decreased glutamate uptake activity in both the frontoparietal cortex and hippocampus without altering the immunocontent of either GLT-1 or GLAST. …”
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    Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype
  19. 40079
    “…On the contrary, reduced post-ischemic functional deficits due to NPC delivery were independent of transplantation paradigms. NPC-induced neuroprotection after acute cell delivery was due to stabilization of the blood–brain barrier (BBB), reduction in microglial activation and modulation of both peripheral and central immune responses. …”
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    Effects of acute versus post-acute systemic delivery of neural progenitor cells on neurological recovery and brain remodeling after focal cerebral ischemia in mice
  20. 40080
    “…These processes included the overarching perspective or point of reference of respondents (positionality), the frameworks used to describe the core concepts (paradigms, theories and models), and the way social and environmental factors were considered to act. …”
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    What is mental health? Evidence towards a new definition from a mixed methods multidisciplinary international survey
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