“…CONCLUSIONS: We validated two experimental design paradigms for cDNA microarray experiments capable of detecting small (<2-fold) changes in gene expression with excellent fidelity that revealed potentially important genes associated with the anti-proliferative effects of neuregulin on MCF10AT breast epithelial cells.…”
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“…In total, 25 male and 20 female C57BL/6J mice, weaned after three (W3) or four (W4) weeks of age, were subjected to a series of behavioural paradigms widely used to assess anxiety-like behaviour, exploratory locomotion, and nest building performance. …”
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“…Using a similar fMRI approach, we use two paradigms that elicit a strong ventral striatum (VS) blood oxygen-level dependency (BOLD) response in a sample of young, healthy individuals (N=82). …”
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“…Notwithstanding, within the scientific culture of the 21(st) Century all healthcare paradigms require evidential support which in regard these early concepts are in large part, absent. …”
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“…The current study employed two task paradigms to evaluate whether treatment-induced changes depend on the probed cognitive domain. …”
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“…Future studies should extend these findings by employing larger sample sizes, by investigating specific task-based paradigms in these patients and by exploring the implications for treatment.…”
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“…In normal-hearing listeners, rippled-spectrum discrimination was psychophysically investigated in both silence and with a simultaneous masker background using the following two paradigms: measuring the ripple density resolution with the phase-reversal test and measuring the ripple-shift threshold with the ripple-shift test. …”
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“…Validated cognitive-behavioral paradigms were used to assess both mTBI and PTSD-like behavior on days 7–14 following the blast. …”
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“…METHODS: Before treatment, 38 SAD patients completed implicit and explicit emotion regulation paradigms during fMRI. Implicit regulation involved attentional control over negative distractors. …”
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“…The feeling of owning and controlling the body relies on the integration and interpretation of sensory input from multiple sources with respect to existing representations of the bodily self. Illusion paradigms involving multisensory manipulations have demonstrated that while the senses of ownership and agency are strongly related, these two components of bodily experience may be dissociable and differentially affected by alterations to sensory input. …”
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“…We evaluated several screening paradigms and incorporated pharmacokinetic monitoring to establish drug exposure levels. …”
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“…We suggest that future research will benefit from the development of standardized experimental paradigms, and common principles for recording and reporting environmental conditions, especially light spectra and intensities.…”
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“…However, the BrainMap.org data analyses also showed that the aforementioned segregations are generated by paradigms in which subjects act in response to conditional stimuli rather than while driven by their own intentions. …”
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“…Motor adaptation paradigms provide a quantitative method to study short-term modification of motor commands. …”
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“…By integrating recently described, though sporadic information of pivotal adhesive and chemokine homing signatures within the tumor microenvironment with better established paradigms of T cell trafficking under homeostatic or infectious disease scenarios, we seek to refine currently incomplete models of T(eff) cell entry into tumor tissue. …”
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“…With the emerging utility of microarrays for cancer prognosis, it will be important to establish paradigms to meta-analyze disparate gene expression data for prognostic signatures of potential clinical use.…”
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“…We operationalized microscale damage to neurons as the formation of pores on the neuronal membrane based on research using blast paradigms, and in our model, pores were simulated by a change in membrane conductance. …”
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“…For this, we characterized electroencephalograhy dynamics (EEG), the evoked potentials and related neural generators involved in various visual paradigms. Time-frequency analysis showed modulation of alpha-beta oscillations indicating the presence of stronger prediction and after-effects of the 3D-tunnel with respect to the checkerboard. …”
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“…None of the stimulation paradigms resulted in improved WM performance or enhanced WM training gains. …”
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“…Future study of neuromodulation paradigms that leverage adaptive CON-H activation may yield clinically relevant gains in lower limb motor function poststroke.…”
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