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  1. 40761
    “…However, research that seeks to inform health care change may have difficulty translating core components of implementation and improvement sciences within the traditional paradigms used to evaluate efficacy and effectiveness research. …”
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    Standardizing an approach to the evaluation of implementation science proposals
  2. 40762
    “…Furthermore, our results suggest that naturalistic paradigms can dissociate between groups of DoC patients with and without covert awareness based on the functional integrity of brain networks.…”
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    Do Patients Thought to Lack Consciousness Retain the Capacity for Internal as Well as External Awareness?
  3. 40763
    “…A shift towards personalised cancer management based on mutation profiling offers the possibility of new treatment paradigms. This study has explored whether actionable, oncogenic driver mutations are present in CUP that have potential to better inform treatment decisions. …”
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    Genetic characterisation of molecular targets in carcinoma of unknown primary
  4. 40764
    “…These data are helpful in framing the shifting paradigms in paediatric appendicitis because it adds transparency to the debate.…”
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    Publication status of completed registered studies in paediatric appendicitis: a cross-sectional analysis
  5. 40765
    “…There was a discordance between paradigms regarding emerging concepts. Four concepts emerged from qualitative papers which were not present in quantitative papers: (1) expert by experience, (2) vigilance, (3) shared care and (4) time. …”
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    ’Who Cares?' The experiences of caregivers of adults living with heart failure, chronic obstructive pulmonary disease and coronary artery disease: a mixed methods systematic review
  6. 40766
    “…As a novel contribution, the reviewed BCI control paradigms for wearable LL and assistive-robots are presented by a general control framework fitting in hierarchical layers. …”
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    EEG-Based BCI Control Schemes for Lower-Limb Assistive-Robots
  7. 40767
    “…Our studies are the first to show, using two null mutant models on different genetic backgrounds, that Kcnj9 (−/−) mice demonstrate significantly less severe alcohol withdrawal than wildtype littermates using acute and repeated exposure paradigms. We also demonstrate that Kcnj9 (−/−) voluntarily consume significantly more alcohol (20%, two-bottle choice) than wildtype littermates. …”
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    Distinct Roles for Two Chromosome 1 Loci in Ethanol Withdrawal, Consumption, and Conditioned Place Preference
  8. 40768
    “…The transplantation of Schwann cells (SCs) has been shown to provide tissue preservation and support axon growth and remyelination as well as improve functional recovery across a diverse range of experimental spinal cord injury (SCI) paradigms. The autologous use of SCs has progressed to Phase 1 SCI clinical trials in humans where their use has been shown to be both feasible and safe. …”
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    Schwann Cell Transplantation Subdues the Pro-Inflammatory Innate Immune Cell Response after Spinal Cord Injury
  9. 40769
    “…While the deficits were typically more pronounced in homozygotes, an intermediate phenotype was observed for heterozygotes in many paradigms. As in other Shank3 mouse models, stereotypies, including increased grooming, were observed. …”
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    Behavioral Phenotyping of an Improved Mouse Model of Phelan–McDermid Syndrome with a Complete Deletion of the Shank3 Gene
  10. 40770
    “…Similarly, in cueing paradigms (where, on cued trials, a cued target requires a speeded response), cues are known to speed up response times (RTs), suggesting that motor preparation has occurred. …”
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    Proactive Inhibition Activation Depends on Motor Preparation: A Single Pulse TMS Study
  11. 40771
    “…A better understanding of how various causal and/or risk factors affecting disease onset and progression will enhance the likelihood of conceiving effective treatment paradigms, which may involve personalized treatment strategies for individual patients at varying stages of disease progression.…”
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    Amyloid, tau, pathogen infection and antimicrobial protection in Alzheimer’s disease –conformist, nonconformist, and realistic prospects for AD pathogenesis
  12. 40772
    “…Collectively, our results demonstrate that the beneficial effects of long-term exposure to fish oil-enriched diet in behavioral paradigms known to recapitulate diverse abnormalities related to the depressive state specifically in mice with a partial loss of BDNF. …”
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    Anxiolytic- and Antidepressant-Like Effects of Fish Oil-Enriched Diet in Brain-Derived Neurotrophic Factor Deficient Mice
  13. 40773
    “…To study how radiation affects neurogenesis, we combine phenotyping of subpopulations of hippocampal neural stem and progenitor cells with double- and triple S-phase labeling paradigms. Using this approach, we reveal new features of division, survival, and differentiation of neural stem and progenitor cells after exposure to gamma radiation. …”
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    Radiation Induces Distinct Changes in Defined Subpopulations of Neural Stem and Progenitor Cells in the Adult Hippocampus
  14. 40774
    “…Only few studies using varied paradigms and often overlapping samples have been conducted. …”
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    Functional Neuroimaging Correlates of Aggression in Psychosis: A Systematic Review With Recommendations for Future Research
  15. 40775
    “…Additional trainee oversight and education, improved electronic health record tools, and novel academic rounding paradigms are needed to address this potential source of medical error.…”
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    Data Omission by Physician Trainees on ICU Rounds*
  16. 40776
    “…BACKGROUND: Archipelagos of islands have played an important role in shaping some of the paradigms of biology, including the theory of the evolution of species. …”
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    The ethnobotany and biogeography of wild vegetables in the Adriatic islands
  17. 40777
    “…CONCLUSIONS: These findings suggest that the leaflets would be appropriate to promote healthy eating through 2 distinct approaches (health and pleasure paradigms) and propose that different effects on attitude could be observed from these 2 approaches.…”
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    Promoting Healthy Eating in Adults: An Evaluation of Pleasure-Oriented versus Health-Oriented Messages
  18. 40778
    “…Also, most standard paradigms investigating individual behavioral differences are framed in a fearful context, therefore the present study aimed to add a test in a more positive context, the feeding context. …”
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    Testing for Behavioral and Physiological Responses of Domestic Horses (Equus caballus) Across Different Contexts – Consistency Over Time and Effects of Context
  19. 40779
    “…Topics of discussion include the crosstalk between cartilage and bone, the efficacy of diagnostic procedures, the origins of joint pain, current and emerging treatment paradigms, and suitable preclinical animal models for safety and efficacy assessment of novel osteochondral therapies. …”
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    Beyond Cartilage Repair: The Role of the Osteochondral Unit in Joint Health and Disease
  20. 40780
    “…Previous studies of inattentional blindness using computer paradigms report higher incidence of this effect in older compared to younger adults. …”
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    Inattentional Blindness During Driving in Younger and Older Adults
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