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  1. 40901
    “…RATIONALE: Recently, experimental paradigms have been developed to strengthen automatic avoidance or inhibitory responses for smoking cues. …”
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    “Push it!” or “Hold it!”? A comparison of nicotine-avoidance training and nicotine-inhibition training in smokers motivated to quit
  2. 40902
    “…Despite the development of predictive biomarkers to shape treatment paradigms and outcomes, de novo EGFR TKI resistance advanced non-small cell lung cancer (NSCLC) remains an issue of concern. …”
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    Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer
  3. 40903
    “…Trained men (n = 15, age: 23 ± 3 years; training experience: 7 ± 3 years) performed unilateral lower-body training for 6 weeks (3× weekly), where single legs were randomly assigned to HV and HL paradigms. Vastus lateralis (VL) biopsies were obtained prior to study initiation (PRE) as well as 3 days (POST) and 10 days following the last training bout (POSTPR). …”
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    Effects of High-Volume Versus High-Load Resistance Training on Skeletal Muscle Growth and Molecular Adaptations
  4. 40904
    “…Due to its simplicity and practicality, more patients with T2D can benefit from subgroup specific treatment paradigms.…”
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    Validation of type 2 diabetes subgroups by simple clinical parameters: a retrospective cohort study of NHANES data from 1999 to 2014
  5. 40905
    “…In line with grand demands in novel PGML principles, this work builds a bridge between extensive physics-based theories and data-driven modeling paradigms and paves the way for using hybrid physics and machine learning modeling approaches for next-generation digital twin technologies.…”
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    Multi-fidelity information fusion with concatenated neural networks
  6. 40906
    por Flory, Andi, Kruglyak, Kristina M., Tynan, John A., McLennan, Lisa M., Rafalko, Jill M., Fiaux, Patrick Christian, Hernandez, Gilberto E., Marass, Francesco, Nakashe, Prachi, Ruiz-Perez, Carlos A., Fath, Donna M., Jennings, Thuy, Motalli-Pepio, Rita, Wotrang, Kate, McCleary-Wheeler, Angela L., Lana, Susan, Phillips, Brenda, Flesner, Brian K., Leibman, Nicole F., LaDue, Tracy, Tripp, Chelsea D., Coomber, Brenda L., Woods, J. Paul, Miller, Mairin, Aiken, Sean W., Wolf-Ringwall, Amber, Borgatti, Antonella, Kraska, Kathleen, Thomson, Christopher B., Kosanovich Cahalane, Alane, Murray, Rebecca L., Kisseberth, William C., Camps-Palau, Maria A., Floch, Franck, Beaudu-Lange, Claire, Klajer-Peres, Aurélia, Keravel, Olivier, Fribourg-Blanc, Luc-André, Mazetier, Pascale Chicha, Marco, Angelo, McLeod, Molly B., Portillo, Erin, Clark, Terry S., Judd, Scott, Feinberg, C. Kirk, Benitez, Marie, Runyan, Candace, Hackett, Lindsey, Lafey, Scott, Richardson, Danielle, Vineyard, Sarah, Tefend Campbell, Mary, Dharajiya, Nilesh, Jensen, Taylor J., van den Boom, Dirk, Diaz, Luis A., Grosu, Daniel S., Polk, Arthur, Marsal, Kalle, Hicks, Susan Cho, Lytle, Katherine M., Holtvoigt, Lauren, Chibuk, Jason, Chorny, Ilya, Tsui, Dana W. Y.
    Publicado 2022
    “…Cancer is the leading cause of death in dogs, yet there are no established screening paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived genomic alterations in cell-free DNA in blood are being adopted for multi-cancer early detection in human medicine and are now available for veterinary use. …”
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    Clinical validation of a next-generation sequencing-based multi-cancer early detection “liquid biopsy” blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study
  7. 40907
    “…Infusion of an IGF-1 neutralizing antibody (nAb; 160 ng/side) into the mPFC 15 min before or 2 h after ketamine injection blocked the antidepressant-like effects of ketamine in three different behavioral paradigms (forced swim, female urine sniffing, and novelty-suppressed feeding tests were conducted 1, 3 and 4 days post-ketamine, respectively). …”
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    IGF-1 release in the medial prefrontal cortex mediates the rapid and sustained antidepressant-like actions of ketamine
  8. 40908
    “…The wealth of molecular information available and the pace at which new data are acquired suggest that methods for minimally invasive biomarker collection could dramatically alter our understanding of skin disease and positively impact treatment paradigms. METHODS: A chemical method was optimized to covalently modify custom dermal patches with single-stranded DNA that could bind to messenger RNA. …”
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    Minimally Invasive Skin Transcriptome Extraction Using a Dermal Biomarker Patch
  9. 40909
    “…The ‘hero’s journey’ concept which has been applied to other illness paradigms for motivation successfully the was adapted to describe surgery as a transformative experience. …”
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    Design and implementation of a novel patient-centered empowerment approach for pain optimisation in children undergoing major surgery
  10. 40910
    “…Anti-amnesic effects were determined employing the open field test, elevated plus maze (EPM), Morris water maze (MWM), and Y-maze paradigms. RESULTS: The in vitro cholinesterase assays disclosed a concentration-dependent inhibition of both AChE and BuChE with IC(50) values of 28.48 and 44.86 µg/mL for the ASEE extract and 32.04 and 50.26 µg/mL for the ASB extract against AChE and BuChE respectively. …”
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    The Neuroprotective Propensity of Organic Extracts of Acacia stenophylla Bark and Their Effectiveness Against Scopolamine-/Diazepam-Induced Amnesia in Mice
  11. 40911
    “…Different methods (e.g., Ambulatory Assessment) and stress reactivity paradigms (e.g., Trier Social Stress Test / TSST) in laboratory settings are often used to investigate basic mechanisms of this process. …”
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    Psychosocial stress induction in vivo vs. in virtuo and the influence of a health app on the acute stress reaction in youths: a study protocol for a randomized controlled trial
  12. 40912
    por Gokula, Veda, Terrero, David, Joe, Bina
    Publicado 2022
    “…On the clinical research front, Christopher Cooper and colleagues lead the CORAL trials and contributed importantly to the investigations on renal artery stenosis treatment paradigms. Hypertension research at this institution has not only provided these pioneering insights, but also grown careers of scientists as leaders in academia as University Presidents and Deans of Medical Schools. …”
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    Six Decades of History of Hypertension Research at the University of Toledo: Highlighting Pioneering Contributions in Biochemistry, Genetics, and Host-Microbiota Interactions
  13. 40913
    “…Preclinical and clinical studies have evidenced that effective targeted therapy treatment designed against receptor tyrosine kinases (RTKs) in different solid tumor paradigms is predicated on simultaneous inhibition of both the PI3K and MEK intracellular signaling pathways. …”
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    Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1
  14. 40914
    “…More detailed studies are required to understand which targets precociously react with CuO NPs, but these results introduce new paradigms for the toxicity of the metal-based NPs, beyond the Lysosomal-Enhanced Trojan horse-related mechanism, and open-up new opportunities to investigate the interactions and effects at the bio-interface for designing safer as well as more effective CuO-based biocides.…”
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    Biological mechanism of cell oxidative stress and death during short-term exposure to nano CuO
  15. 40915
    por Rajashekar, S., Jain, Alka
    Publicado 2023
    “…Attaining sustainable competitive advantage in changing paradigms of the business world is possible through highly engaged employees, and holistic well-being is considered one of employee engagement's most important drivers (Ryder, G., & Director-General, I. (2020). …”
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    A Thematic Analysis on “Employee Engagement in IT Companies from the Perspective of Holistic Well-being Initiatives”
  16. 40916
    por Stott, Matthew
    Publicado 2019
    “…It is important therefore, to quantify the statistical properties for such fields under the assumption of a multifarious scalar component in the low energy spectrum and the viability these ubiquitous elements of string models provide correct theoretic solutions to cosmological paradigms. The powerful asymptotic nature of the limiting spectral distributions of large random matrices has incorporated itself into various areas associated to multi-field axion cosmology. …”
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    Effective multi-axion cosmology and constraints from black hole superradiance
  17. 40917
    por Díaz Méndez, Marcela Mabel
    Publicado 2023
    “…Warning, in addition, in its correlation with power, possible changes in socio-legal paradigms and possible cracks or fractures in the biopower of States, especially in Latin America.Keywords: Collective, courageous speech, feminism, power, biopower.…”
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    El discurso valiente del colectivo feminista del siglo XXI
  18. 40918
    por Xiong, Wei
    Publicado 2023
    “…Because the polariton states are half-matter and half-light, whose energy is shifted from the parental states, polaritons are predicted to modify chemistry under thermally activated conditions, leading to an exciting and emerging field known as polariton chemistry that could potentially shift paradigms in chemistry. Despite several published results supporting this concept, the chemical physics and mechanism of polariton chemistry remain elusive. …”
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    Molecular Vibrational Polariton Dynamics: What Can Polaritons Do?
  19. 40919
    “…Motor imagery is one of the significant control paradigms in the BCI field, and many datasets related to motor tasks are open to the public already. …”
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    Review of public motor imagery and execution datasets in brain-computer interfaces
  20. 40920
    “…*COMMUNICATION: The behavioral scientists in community engagement do not necessarily share paradigms (e.g., public health, psychology, and social work). …”
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    439 Research Dynamics within a New Multi-Institutional Cross-Disciplinary Translational Team (MCTT): A Formative Study
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