“…Changes in brain responses to emotional and cognitive stimuli will be examined with three functional magnetic resonance imaging (fMRI) paradigms. In addition, a resting state MRI will be acquired to investigate possible changes in brain connectivity. …”
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“…The included studies were then divided into subgroups according to different task paradigms. Then, an activation likelihood estimation algorithm (ALE) was performed in the different meta-analyses to identify whether brain regions showed consistent effects. …”
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“…Humoral immunity to factor VIII (FVIII) represents a significant challenge for the treatment of patients with hemophilia A. Current paradigms indicate that neutralizing antibodies against FVIII (inhibitors) occur through a classical CD4 T cell, germinal center (GC) dependent process. …”
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“…In the forthcoming sections, we provide a detailed overview of the clinical data, treatment paradigms, and considerations in this population. This review provides a comprehensive overview of existing clinical data and clinical considerations in the older adult head and neck cancer population. …”
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“…In neonates, where functional MRI is limited to very few paradigms, rsfMRI was shown to be a relevant tool to explore regional interactions of brain networks. …”
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“…Therefore, new diagnostic paradigms are needed to predict treatment response and inform clinical decision-making. …”
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“…Consequently, GSCs have emerged as targets of interest in new treatment paradigms. Here, we review the unique properties of GSCs, including their interactions with the hypoxic microenvironment that drives their proliferation. …”
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“…Furthermore, we aim to provide a pathway to an effective use of stimulation paradigms in future studies. METHODS: Preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines were followed. …”
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“…Nowadays, this knowledge has not only allowed the emergence of new etiologic paradigms for bone disease but also a new dynamic approach on the concept of osseointegration and MBL around oral implants, re‐evaluating our older disease oriented outlook. …”
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“…We experiment on six public Twitter sentiment datasets, the STS-Gold dataset, the Obama-McCain Debate (OMD) dataset, the healthcare reform (HCR) dataset and the SemEval2017 Task 4A, 4B and 4C on a heterogeneous classifier ensemble comprising fourteen individual classifiers from different paradigms. Results from the experimental study indicate that CFS supports in attaining a higher classification accuracy with up to 50% lesser features compared to count vectorizer approach. …”
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“…Technological advances may enhance organism identification but challenge existing paradigms of care. More studies are needed to better delineate the intersection of diagnostic advancements with patient care standards. …”
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“…Immune checkpoint inhibition (ICI) therapy has shifted treatment paradigms in many types of cancers, and recent clinical data have shown promise for improving MPM treatment. …”
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“…INTRODUCTION: Poor outcomes in glioblastoma patients, despite advancing treatment paradigms, indicate a need to determine non-physiologic prognostic indicators of patient outcome. …”
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“…We will conclude with a perspective of how multiplexed-engineered and gene edited cell products may upend today’s treatment paradigms as they evolve into the next generation of more potent cellular immunotherapies.…”
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“…Finally, we summarize the therapeutic strategies aimed at preventing the severe forms of COVID-19 that target ACE2. Changing paradigms may help improve patients’ therapy.…”
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“…This paper will document the book’s two fundamental errors: namely, its Kantian-influenced ontological idealism and its claims of incommensurability between competing paradigms. Both had significant flow-on effects. Although the book had many positive features, this paper will document how most of these ideas and insights were well established in HPS literature at the time of its 1962 publication. …”
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“…These results suggest that development of SEIs in AdV D8 conjunctivitis is largely attributable to pathologic viral sequence variants within the D8 type and establishes machine learning paradigms as a powerful technique for understanding viral pathogenicity.…”
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“…The COVID-19 pandemic has provided an abundant amount of data that allow for thorough testing of disease modelling assumptions, as well as how we think about classical infectious disease modelling paradigms. OBJECTIVE: We aim to assess the appropriateness of model parameter estimates and prediction results in classical infectious disease compartmental modelling frameworks given available data types (infected, active, quarantined, and recovered cases) for situations where just one data type is available to fit the model. …”
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“…Further validation is needed, which sets new paradigms for investigation in clinical research based on tumor biology for treatment allocation and not only on clinical stratification tools. …”
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“…With further prospective validation, ctDNA TF could be incorporated into care paradigms to enable precision escalation and de-escalation of cancer therapy based on patient-level tumor biology.…”
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