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  1. 41241
    “…Moreover, depression-like behaviors of ST2 Tg mice were observed in two well-established behavioral paradigms, the forced swimming test and the tail suspension test. …”
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  2. 41242
  3. 41243
    “…BACKGROUND: Treatment paradigms for metastatic non-small cell lung cancer are increasingly based on biomarker-driven therapies, with the most common alteration being mutation in the epidermal growth factor receptor (EGFR). …”
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  4. 41244
    por Brenneis, Georg
    Publicado 2022
    “…One key issue concerns the marine horseshoe crabs (Xiphosura), which recent studies recover either as sister group of terrestrial Arachnida or nested within the latter, with significant impact on postulated terrestrialization scenarios and long-standing paradigms of ancestral chelicerate traits. In potential support of a nested placement, previous neuroanatomical studies highlighted similarities in the visual pathway of xiphosurans and some arachnopulmonates (scorpions, whip scorpions, whip spiders). …”
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  5. 41245
    “…CONCLUSIONS: In a post hoc analysis of one of the largest ASUC cohorts collected to date, we report an emerging UK ambulatory practice which challenges treatment paradigms. However, our analysis remains underpowered to detect key outcome measures and further studies exploring clinical and cost-effectiveness as well as patient and physician acceptability are needed. …”
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  6. 41246
    “…Several factors could contribute to these mixed findings, including boredom and low motivation. Indeed, training paradigms are repetitive, which can lead to disengagement and high dropout rates. …”
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  7. 41247
    “…Precision medicines can help shift treatment paradigms toward treat-to-target, with clinical remission as the ultimate therapeutic goal in severe asthma. …”
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  8. 41248
    “…The SLF II appears to be a very important anatomical neural correlate involved in such learning paradigms. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12984-022-01042-2.…”
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  9. 41249
    “…Finally, the spatial salinity distribution assessment in the study area ascertained the high predictability potential of the ANFIS-OA hybrid with B-RF feature selection compared to other paradigms. The most important novelty of this research is using a robust framework comprised of the non-linear data filtering technique and a new hybrid neuro-computing approach, which can be considered as a reliable tool to assess water salinity in coastal aquifers.…”
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  10. 41250
  11. 41251
    “…METHODS: A multi-class, multiple binary classifier framework was used to decode three kinesthetically imagined movements (motor imagery of left arm, right arm, and feet), and relaxed state. Three game paradigms were used for training i.e., NeuroSensi, Triad, and Cybathlon Race: BrainDriver. …”
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  12. 41252
  13. 41253
    “…In conclusion, our result may help to shed new light on the “gut microbiota-immunity axis,” lipid metabolites, and duodenal immune response in overt CD and pCD patients, opening new paradigms in understanding the pathogenesis behind CD progression.…”
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  14. 41254
    “…Dominant, Western approaches to suicide prevention—typically involving individual-level efforts for behavioural change via mental health professional intervention—by themselves have largely failed at addressing suicide in Indigenous populations, possibly due to cultural misalignment with Indigenous paradigms. Consequently, many Indigenous communities, organizations and governments have been undertaking more cultural and community-based approaches to suicide prevention. …”
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  15. 41255
    “…Bayesian methods were used in 28.6% (n = 28) of platform RCTs and frequentist methods in 66.3% (n = 65) of trials, including 1 (1%) that used methods from both paradigms. Out of the twenty-five trials with peer-reviewed publication of results, seven trials used Bayesian methods (28%), and of those, two (8%) used a predefined sample size calculation while the remainder used pre-specified probabilities of futility, harm, or benefit calculated at (pre-specified) intervals to inform decisions about stopping interventions or the entire trial. …”
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  16. 41256
    “…Differences in the operational paradigms among provider groups of varying types and sizes may explain their varying extents of health information exchange for sending and receiving health information. …”
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  17. 41257
    “…To address this issue, risk stratification, machine learning, and linear regression paradigms have been proposed as potential predictive solutions. …”
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  18. 41258
    “…Contemporary management paradigms involve advanced molecular imaging and multimodal treatment with intensified prostate-directed or systemic treatment—resources more readily available at high-volume centers. …”
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  19. 41259
    por Onuigbo, Macaulay
    Publicado 2013
    “…Current renoprotection paradigms depend wholly and entirely on angiotensin blockade; however, these agents [angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs)] have proved to be imperfect renoprotective agents. …”
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  20. 41260
    “…Studies using a variety of paradigms involving self-performed actions argue in favor of perspective taking confusion in hallucination-prone subjects. …”
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