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  1. 7161
    “…AIMS: We applied the restricted mean survival time (RMST) to analyse the survival data reported in the PARADIGM‐HT trial in which sacubitril + valsartan was studied in comparison with enalapril in patients with heart failure. …”
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    The restricted mean survival time as a replacement for the hazard ratio and the number needed to treat in long‐term studies
  2. 7162
    “…PURPOSE: In the treatment of patients with metastatic cancer, the current paradigm states that metastasis-directed therapy does not prolong life. …”
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    Revisiting a Null Hypothesis: Exploring the Parameters of Oligometastasis Treatment
  3. 7163
    “…We describe a novel approach for experimental High-Energy Physics (HEP) data analyses that is centred around the declarative rather than imperative paradigm when describing analysis computational tasks. …”
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    Scalable Declarative HEP Analysis Workflows for Containerised Compute Clouds
  4. 7164
    “…Recent studies have shown that this paradigm cannot be maintained for SubAB, since SubA alone was demonstrated to intoxicate human epithelial cells in vitro. …”
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    Cytotoxic Effects of Recombinant StxA2-His in the Absence of Its Corresponding B-Subunit
  5. 7165
    “…Since 2015, immunotherapy has been changing the paradigm of NSCLC treatment in different settings and has contributed to improve the quality of life of these patients. …”
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    Immunotherapy in non-small cell lung cancer: Update and new insights
  6. 7166
    por Yahya, Jumana
    Publicado 2021
    “…Despite remaining a minority, situated views and practices based on these theories have planted the seeds of a paradigm shift in the self-control literature, moving away from the idea that self-control is an ability limited to the borders of the brain. …”
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    Breaking Beyond the Borders of the Brain: Self-Control as a Situated Ability
  7. 7167
    “…Our results show that the Antarctocentric palaeogeographic paradigm can reconcile geological data and simulated Cambrian climate. …”
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    Quantitative comparison of geological data and model simulations constrains early Cambrian geography and climate
  8. 7168
    “…A standard paradigm of localization microscopy involves extension from two to three dimensions by engineering information into emitter images, and approximation of errors resulting from the field dependence of optical aberrations. …”
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    Accurate localization microscopy by intrinsic aberration calibration
  9. 7169
    “…SIMPLE SUMMARY: Lymphoma research is a paradigm of integrating basic and applied research within the fields of molecular marker-based diagnosis and therapy. …”
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    An Overview on Diffuse Large B-Cell Lymphoma Models: Towards a Functional Genomics Approach
  10. 7170
    “…In this work, we propose to exploit collaborative grippers in a novel paradigm in which these devices can be easily attached and detached from the robot arm and used also independently from it. …”
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    Detachable Robotic Grippers for Human-Robot Collaboration
  11. 7171
    “…Energy-specific collimation is still a new paradigm in PBS and the 2 specific collimators tailored toward PBS are presented including the dynamic collimation system (DCS) and the Mevion Adaptive Aperture. …”
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    Innovations and the Use of Collimators in the Delivery of Pencil Beam Scanning Proton Therapy
  12. 7172
    “…OBJECTIVE: To propose a paradigm for a scalable time-aware clinical data search, and to describe the design, implementation and use of a search engine realizing this paradigm. …”
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    ACE: the Advanced Cohort Engine for searching longitudinal patient records
  13. 7173
    “…Bipolar Galvanic Vestibular Stimulation (GVS) was applied during the Misalignment Paradigm. A Sham stimulation condition was also included to control for non-specific effects. …”
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    The vestibular system modulates the contributions of head and torso to egocentric spatial judgements
  14. 7174
    por Omidi, Yadollah, Omidian, Hossein
    Publicado 2021
    “…Since the medication is a highly trusted and needed public enterprise, the drug discovery and development paradigm should be practiced at the highest speed with maximum transparency and accountability.…”
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    Transformative dynamism in pharmaceutical and biomedical research: Complexity of integration of innovative R & D hubs
  15. 7175
    “…This paper presents an experimental paradigm that uses a physical human-robot collaborative task environment to explore emergent human-robot co-adaptions and derive the interaction patterns (i.e., the targeted awareness of co-adaptation). …”
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    Identifying Interaction Patterns of Tangible Co-Adaptations in Human-Robot Team Behaviors
  16. 7176
    “…However, this paradigm does not explain why ~20%–30% of individuals with Na(V)1.2 deficiency still develop seizures. …”
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    Severe deficiency of the voltage-gated sodium channel Na(V)1.2 elevates neuronal excitability in adult mice
  17. 7177
    “…To test whether these expectations translate to actual harm to experienced autonomy, three online studies were conducted. The paradigm used in all studies was that participants were asked to voluntarily participate in a longer version of the questionnaire. …”
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    The effect of nudges on autonomy in hypothetical and real life settings
  18. 7178
    “…This study explored the feasibility of applying eye tracking technology to quantify CS as a first step toward developing a testing paradigm that will not rely on observers’ behavioral or language abilities. …”
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    The Integration of Eye Tracking Responses for the Measurement of Contrast Sensitivity: A Proof of Concept Study
  19. 7179
    “…Two CIH protocols were tested: A mild CIH paradigm (5/6 hypoxic (5% O(2)) cycles/h, 10.5 h/day) during 35 days and a severe CIH paradigm (30 hypoxic (5% O(2)) cycles, 8 h/day) during 15 days. …”
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    Chronic Intermittent Hypoxia Induces Early-Stage Metabolic Dysfunction Independently of Adipose Tissue Deregulation
  20. 7180
    por Huang, Xinxin, Izumi, Shin-Ichi
    Publicado 2021
    “…In addition, the passive IPD experimental paradigm is the main experimental paradigm for exploring neural activity in IPD cognition, with the parietal lobe, motor areas, prefrontal lobe, and amygdala being the main brain areas involved. …”
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    Neural Alterations in Interpersonal Distance (IPD) Cognition and Its Correlation with IPD Behavior: A Systematic Review
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