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  1. 7781
    “…Although classic chemo(immuno)therapy is still the standard of care for patients in need of treatment, this paradigm might change in the near future with the advent of new therapeutic agents targeting major pathogenic pathways in CLL.…”
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    Advances in treating chronic lymphocytic leukemia
  2. 7782
    “…Given their importance, these parameters should be carefully considered for the design of future clinical trials testing this immunotherapeutic paradigm in prostate cancer patients.…”
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    Prostate cancer: Important steps and considerations in the design of therapeutic vaccines
  3. 7783
    “…The convergence of these biomedical models with the ancient paradigm of TCM may provide a new insight into scientifically verifiable diagnostic and therapeutic approaches for these common disorders.…”
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    Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine
  4. 7784
    por Hanasono, Matthew M.
    Publicado 2014
    “…More importantly, there has been a paradigm shift toward seeking not only to achieve reliable wound closure to protect vital structures, but also to reestablish normal function and appearance. …”
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    Reconstructive Surgery for Head and Neck Cancer Patients
  5. 7785
    por Bernard, Bruno A.
    Publicado 2016
    “…The interdependence and complementary roles of these influences allow us to propose that the hair follicle is a true paradigm of a “Yin Yang” type, that is a cold/slow-hot/fast duality. …”
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    Advances in Understanding Hair Growth
  6. 7786
    “…Now, over 30 years later, this yeast and its receptors continue to provide a pathfinding experimental paradigm for investigating GPCR-initiated signaling and its regulation, as described in this retrospective overview.…”
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    Heterotrimeric G Protein-coupled Receptor Signaling in Yeast Mating Pheromone Response
  7. 7787
    por Parnham, Arie, Serefoglu, Ege Can
    Publicado 2016
    “…An enhanced awareness of sexual dysfunctions in the recent decades has lead to an increase in scientific research that has challenged the traditional paradigm regarding PE. This has also enabled to establish a universal definition and classification of the disease. …”
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    Classification and definition of premature ejaculation
  8. 7788
    por Birch, Kean
    Publicado 2006
    “…Finally it will consider how the manufacture of scarcity - in order to produce the bioeconomy - has led to a problematic focus on a specific innovation paradigm that may prove detrimental to the development and distribution of new biotechnologies.…”
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    The Neoliberal Underpinnings of the Bioeconomy: the Ideological Discourses and Practices of Economic Competitiveness
  9. 7789
    por Innocenti, Giorgio M.
    Publicado 2017
    “…This is due to the complexity of the networks, their heterogeneity, and to the multiple computations performed by the axons. Poffenberger’s paradigm is one example of a simple task aimed at characterizing the temporal properties of an interhemispheric network which has remained elusive to this day.…”
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    Network causality, axonal computations, and Poffenberger
  10. 7790
    “…The treatment of advanced laryngeal cancer has undergone a paradigm shift in recent years, with an increase in chemoradiation for organ preservation and a decrease in primary surgery. …”
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    Contemporary management of advanced laryngeal cancer
  11. 7791
    por Lawton, Rebecca
    Publicado 2018
    “…Mannion and Braithwaite outline a new paradigm for studying and improving patient safety – Safety II. …”
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    It Ain’t What You Do (But the Way That You Do It): Will Safety II Transform the Way We Do Patient Safety?: Comment on "False Dawns and New Horizons in Patient Safety Research and Practice"
  12. 7792
    “…Physicians should familiarize themselves with such paradigm shifts.…”
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    Remaining challenges in the diagnosis of early stage cardiac sarcoidosis
  13. 7793
    “…This observation supports a new paradigm of gonorrhea transmission in which oropharyngeal gonorrhea can be transmitted through tongue kissing.…”
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    Oropharyngeal Gonorrhea in Absence of Urogenital Gonorrhea in Sexual Network of Male and Female Participants, Australia, 2018
  14. 7794
    “…This is achieved following a new paradigm of using ART‐loaded NFN in infusion system of hydrophobic drug eluting nanocarriers, adapted to clinical applications. …”
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    Unlocking Nanocarriers for the Programmed Release of Antimalarial Drugs
  15. 7795
    “…In this review we highlight the difficulties and limitations of this popular paradigm, as well as the relations to alternative instruments ranging from survey measures to neurochemical manipulations and neuroimaging.…”
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    Trust Games and Beyond
  16. 7796
    por Burns, Devin
    Publicado 2019
    “…This data contains response times for 19 participants from a Systems Factorial Technology paradigm using visual and vibratory cues, as described in “The Balance Between Vision and Touch [1]”. …”
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    A Systems Factorial Technology dataset using visual and tactile cues to guide balance
  17. 7797
    “…MHV-A59 coronavirus infection produces a transient episode of demyelination that is followed by spontaneous remyelination. This paradigm provides a complex lesion environment to examine cellular and molecular mechanisms involved in successful CNS remyelination. …”
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    Coronavirus-Induced Demyelination and Spontaneous Remyelination: Growth factor expression and function
  18. 7798
    “…Here, we review the main players and mechanisms involved in the field. A new research paradigm, which considers also novel contributors, like endothelial cells, is needed to better understand the pathophysiology of immune-mediated cardiovascular disorders and beyond.…”
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    The crosstalk between the cardiovascular and the immune system
  19. 7799
    “…However, much remains to be done, not only for research discovery but also education and outreach, to increase and grow the biofilm paradigm as well as our understanding of the microbial world.…”
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    The establishment of the CBE launched biofilms as a field of specialized research
  20. 7800
    “…It includes ten select papers with methodological and theoretical advances, and demonstrates the usefulness of the network paradigm by applications to current problems.…”
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    Special issue on statistical analysis of networks: Preface by the guest editors
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