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8421“…Using a free-flying learning paradigm, this paper shows that learning performance is impaired in bumble-bees (Bombus terrestris) that are not infected but whose immune system is stimulated non-pathogenically. …”
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8422por Majkowski, J“…The foodborne outbreak paradigm has shifted. In the past, an outbreak affected a small local population, had a high attack rate, and involved locally prepared food products with limited distribution. …”
Publicado 1997
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8423por Kurakin, Alexei“…The present work is intended to demonstrate that most of the paradoxes, controversies, and contradictions accumulated in molecular and cell biology over many years of research can be readily resolved if the cell and living systems in general are re-interpreted within an alternative paradigm of biological organization that is based on the concepts and empirical laws of nonequilibrium thermodynamics. …”
Publicado 2009
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8424por Snoj, Natasa, Bedard, Philippe L, de Azambuja, Evandro, Cardoso, Fatima, Piccart, Martine“…Using the ongoing neoadjuvant trials with HER2 (human epidermal growth factor receptor 2)-directed therapy as a paradigm, this article discusses recent innovations in study design and the challenges of conducting translational research in the neoadjuvant setting.…”
Publicado 2009
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8425“…The advance in genomic technologies has the potential to change this paradigm and add substantial value to current medical practice by providing an integrated approach to guide patient-specific treatment selection using the genetic make-up of the disease and the genotype of the patient. …”
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8426“…We do not agree with the sceptical claim that it is impossible to conceptualise spirituality within a scientific paradigm. Our aims are to 1) provide a brief over-view of critical thinking that might form the basis for a useful definition of spirituality for research and clinical work and 2) demystify the language of spirituality for clinical practice and research.…”
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8427“…We investigated these questions using a turn-reproduction paradigm, where participants were seated on a motion platform equipped with a projection screen and were asked to actively return a combined visual and inertial whole-body rotation around an earth-vertical axis. …”
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8428“…An ontology is similar to a paradigm but has very strict implications for formatting and meaning in a computational context. …”
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8429“…It can be argued that the arrival of the “genomics era” has significantly shifted the paradigm of vaccine and therapeutics development from microbiological to sequence-based approaches. …”
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8430“…In this review, we present a general screening paradigm that is currently being used as part of drug discovery at Schering-Plough and we describe a case study using the Hepatitis C Virus (HCV) protease inhibitor program as an example. …”
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8431“…As evidence-based medicine continues to establish itself as the new paradigm by which medicine is practiced, the need for good reporting for all research designs must also become commonplace as opposed to the exception.…”
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8432por Sharma, Savita“…The paradigm of preventing human papilloma virus (HPV) infection through currently approved vaccines, namely, Gardasil, manufactured by Merck and Co., Inc. …”
Publicado 2008
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8433“…Cellular therapy offers a new paradigm for treatment of heart disease. Stem cell therapies in animal models show that transplantation of various cell preparations improves ventricular function after injury. …”
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8434“…The occupational health scenario is undergoing a paradigm shift in developing countries with rapid industrialization. …”
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8435“…Based on the result of single non-overlapped SCRs, response parameters can be estimated precisely as shown in a paradigm with varying inter-stimulus intervals.…”
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8436por Lee, Byoung Dae, Shin, Joo-Ho, VanKampen, Jackalina, Petrucelli, Leonard, West, Andrew B., Ko, Han Seok, Lee, Yun, Maguire-Zeiss, Kathleen A., Bowers, William J., Federoff, Howard J., Dawson, Valina L., Dawson, Ted M.“…These results establish that LRRK2-induced degeneration of neurons in vivo is kinase dependent and that LRRK2 kinase inhibition provides a potential new neuroprotective paradigm for the treatment of PD.…”
Publicado 2010
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8437“…The T-helper (Th)1/Th2 paradigm has proven to be essential for the understanding of protective adaptive host responses. …”
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8438por Deretic, Vojo“…Autophagy has become a biological paradigm of how eukaryotic cells, especially those that are long lived, maintain their vitality, control the quality of cytoplasmic organelles, and stay alive or die when growth factors are withdrawn and there is an energy or nutrient crisis. …”
Publicado 2010
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8439“…In this study, using the apomorphine-induced motility-alteration behavioural paradigm, single session multiple ECS was found to produce no significant effect while single ECS behaviourally downregulated dopamine postsynaptic receptor functioning one week after the ECS, which effect was also seen (albeit to a lesser extent) a further week later. …”
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8440por Bukowski, Ronald M“…Development of vascular endothelial growth factor inhibitors and phase 3 clinical trials utilizing this class of agents has produced a new treatment paradigm for patients with metastatic renal cell carcinoma (RCC). …”
Publicado 2010
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