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  1. 8441
    por Wu, Cindy, Prachand, Vivek N.
    Publicado 2008
    “…Surgeons are gaining interest in natural orifice surgery because of its minimally invasive nature. The new paradigm shift of using a natural orifice, as opposed to the abdominal wall, as a conduit for entry into the abdomen has resulted in novel solutions to solving difficult surgical problems. …”
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    Reverse NOTES: a Hybrid Technique of Laparoscopic and Endoscopic Retrieval of an Ingested Foreign Body
  2. 8442
    “…This paper describes a new development based on microarray technology which uses ultraviolet light induced DNA damage as a paradigm to determine the position and frequency of DNA damage and its subsequent repair throughout the entire yeast genome.…”
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    A novel method for the genome-wide high resolution analysis of DNA damage
  3. 8443
    por Jutel, Marek, Akdis, Cezmi A.
    Publicado 2011
    “…The discovery of Tregs revolutionized the primary concepts of immune regulation interpreted within the framework of a binary Th1/Th2 paradigm. Tregs play a central role in the maintenance of peripheral homeostasis, the establishment of controlled immune responses, and the inhibition of allergen-specific effector cells. …”
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    T-cell Subset Regulation in Atopy
  4. 8444
    “…Here, we decipher and discuss the key genes implicated in the leukocyte transmigration using the acute inflammation model called as the Dextran Sulphate Sodium (DSS) induced Colitis in mice as a classic paradigm.…”
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    Deciphering the key molecular and cellular events in neutrophil transmigration during acute inflammation
  5. 8445
    por Baird, MA
    Publicado 2008
    “…However, as the findings and student feedback will attest, many challenges and constraints continue to face educators who seek to situate their curriculum within the reflective practice paradigm.…”
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    Towards the development of a reflective radiographer: challenges and constraints
  6. 8446
    “…Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. …”
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    The functional role of long non-coding RNA in human carcinomas
  7. 8447
    “…Community-based participatory research (CBPR) is a paradigm to study and reduce disparities in health outcomes related to chronic disease. …”
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    Community Advisory Boards in Community-Based Participatory Research: A Synthesis of Best Processes
  8. 8448
    “…We transferred this paradigm to the auditory modality. Prime awareness was manipulated by a reduction of sound intensity level. …”
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    Subliminal Semantic Priming in Speech
  9. 8449
    “…While past attempts to use immunotherapy have failed to dramatically shift the paradigm of care for the treatment of patients with sarcoma, major advances in basic and translational research have resulted, in more recent years, in clinical trial activity that is now beginning to generate promising results. …”
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    Immunotherapeutic Intervention against Sarcomas
  10. 8450
    por Venkatesan, S.
    Publicado 2010
    “…Clinimetrics is explained as a changing paradigm in the design, administration, and interpretation of quantitative tests, techniques or procedures applied to measurement of clinical variables, traits and processes. …”
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    Indian scales and inventories
  11. 8451
    “…Response inhibition and response execution were measured by a stop-signal paradigm. Results show that users and non-users are comparable in terms of response execution but users need significantly more time to inhibit responses to stop signals than non-users.…”
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    Long-Term Effects of Chronic Khat Use: Impaired Inhibitory Control
  12. 8452
    por Mac Master, Frank P.
    Publicado 2010
    “…Given the persistence of symptoms and levels of treatment response, it is clear that the serotonin paradigm of OCD does not fully account for the neurobiology of the disorder, and that further translational research is needed. …”
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    Translational neuroimaging research in pediatric obsessive-compulsive disorder
  13. 8453
    por Backert, Steffen, Tegtmeyer, Nicole
    Publicado 2010
    “…Helicobacter pylori VacA is paradigm of pore-forming toxins which contributes to the pathogenesis of peptic ulceration. …”
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    The Versatility of the Helicobacter pylori Vacuolating Cytotoxin VacA in Signal Transduction and Molecular Crosstalk
  14. 8454
    “…Advances in our understanding of renal cancer biology have led to a new treatment paradigm in renal cancer. Tyrosine kinase inhibitors (TKI), that target the intracellular kinase domain of the VEGF receptor, have become established as the most successful class of agent in this disease. …”
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    Tyrosine Kinase Inhibitors in the Treatment of Advanced Renal Cell Carcinoma: Focus on Pazopanib
  15. 8455
    “…The present paper discusses preventing school bullying from a developmental guidance perspective, using the positive youth development paradigm and promoting the values of harmony and forgiveness at the whole-school level to cultivate a harmonious school culture as a way of combating school bullying.…”
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    Combating School Bullying through Developmental Guidance for Positive Youth Development and Promoting Harmonious School Culture
  16. 8456
    por Wang, Samantha X.Y.
    Publicado 2011
    “…Denny Sakkas of Yale’s Department of Obstetrics, Gynecology, and Reproductive Sciences presented a paradigm shift: using morphological factors along with metabolic, protein, and genetic markers in culture media to enhance embryo selection and IVF success rates.…”
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    The Past, Present, and Future of Embryo Selection in In Vitro Fertilization: Frontiers in Reproduction Conference
  17. 8457
    “…Biologic agents have dramatically shifted the treatment paradigm for rheumatic disease. Use of these agents can decrease disease burden, allow the patient to be weaned from corticosteroids, and reduce the likelihood of relapse. …”
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    Use of Biologic Agents in Ocular Manifestations of Rheumatic Disease
  18. 8458
    por Salje, E. K. H.
    Publicado 2010
    “…The increasing miniaturization of devices as well as the emphasis of recent research on microstructures with length scales of a few nanometres lead to paradigm changes that may impact not only on our scientific understanding of fine-grained structures but also on the way we will develop device materials in the future. …”
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    Multi-scaling and mesoscopic structures
  19. 8459
    “…This article will review the evolving diagnostic and therapeutic approaches in literature, and in the end, propose a paradigm in approaching this group of patients.…”
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    Assessment and Management of Proximal and Incomplete Symptomatic Obstruction of the Lacrimal Drainage System
  20. 8460
    “…The statistical analysis utilized the hypothesis-rich, targeted search unbiased assessment approach, rather than the hypothesis-free, genome-wide agnostic search paradigm. The association of DZIP1 with Parkinson's disease is discussed in the context of a Parkinson's disease stem-cell ageing theory.…”
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    Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease
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