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  1. 8941
    “…Over the last decade, the therapeutic scenario for advanced non-small-cell lung cancer (NSCLC) has undergone a major paradigm shift. Immune checkpoint inhibitors (ICIs) have shown a meaningful clinical and survival improvement in different settings of the disease. …”
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    Immune Checkpoint Inhibitors in “Special” NSCLC Populations: A Viable Approach?
  2. 8942
    “…By limiting the need to launch supplies from the Earth, the paradigm of spaceflight is changed, privileging the vanguard of the utilisation of resources in situ. …”
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    Characterization of Composite Freeze-Dried Aerogels with Simulant Lunar Regolith for Space Applications
  3. 8943
    por Su, Emily J.
    Publicado 2023
    “…Their findings can better individualize patient counseling but, just as compellingly, provide the capacity to identify those pregnancies that are at such considerable risk as to justify enrollment in paradigm-shifting interventional trials that are in the pipeline.…”
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    Scaling the EVERREST of severe, early-onset fetal growth restriction
  4. 8944
    por Raffo, Andrea, Paulsen, Jonas
    Publicado 2023
    “…We classify existing algorithms on the basis of the data representation and pattern recognition paradigm they make use of. Finally, we outline some of the challenges ahead and promising future directions.…”
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    The shape of chromatin: insights from computational recognition of geometric patterns in Hi-C data
  5. 8945
    “…Fecal microbiota transplantation (FMT) and maggot debridement therapy (MDT) represent paradigm-shifting approaches, leveraging biological systems to mitigate AMR. …”
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    Pushing the frontiers in the fight against antimicrobial resistance: the potential of fecal and maggot therapies
  6. 8946
    “…Here, we discuss how emerging virtual staining technologies and machine learning can help to disrupt the standard histopathology workflow and create new avenues for the diagnostic paradigm that will benefit patients and healthcare systems alike via digital pathology.…”
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    Emerging Advances to Transform Histopathology Using Virtual Staining
  7. 8947
    “…The results of IMbrave150 and HIMALAYA have changed the treatment paradigm for HCC and established immune checkpoint inhibition (ICI), either combined with anti-angiogenic therapy or dual ICI, as preferred first-line therapy for eligible patients with aHCC. …”
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    Current Evidence for Immune Checkpoint Inhibition in Advanced Hepatocellular Carcinoma
  8. 8948
    “…Our results contradict the long-standing paradigm that at least one asymmetric ion is required for ionic liquids to be molten at room temperature, and hence open up new and simpler design pathways for these remarkable materials.…”
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    Room temperature ionic liquids with two symmetric ions
  9. 8949
    por Li, Juntan, Jia, Xiaoyong
    Publicado 2023
    “…The exploration and control of NP assembly through such a photo-controlled strategy can open a new paradigm for scientists to deal with “bottom-up” behaviors and develop unprecedented optoelectronic functional materials.…”
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    Photo-Controlled Self-Assembly of Nanoparticles: A Promising Strategy for Development of Novel Structures
  10. 8950
    “…This confirmed previous observations that PA segregation in this organism seems to follow the Escherichia coli paradigm of nucleoid occlusion governing polar localization and asymmetric segregation during vegetative growth. …”
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    Impact of Protein Aggregates on Sporulation and Germination of Bacillus subtilis
  11. 8951
    “…METHODS: This is a qualitative study, within the interpretative paradigm, using the focus group methodology. Eight undergraduate nursing students participated in the study. …”
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    Clinical supervision strategies, learning, and critical thinking of nursing students
  12. 8952
    por Zhang, Lindsay, Vogt, Keith
    Publicado 2023
    “…An experimental auditory paradigm paired with the periodic pain was used to examine auditory encoding and subsequent recognition. …”
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    Psychometric and next day electrodermal activity data from an experiment involving midazolam, ketamine, and painful stimulation
  13. 8953
    por Han, Alex Heunhe, Lee, Dong Hoon
    Publicado 2023
    “…Risk-based authentication (RBA) plays a critical role in the context of the zero trust framework—a paradigm shift that assumes no trust within or outside the network. …”
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    Detecting Risky Authentication Using the OpenID Connect Token Exchange Time
  14. 8954
    “…In this paper, we provide a critical overview of this research with a focus on the RHI paradigm as a tool to study prothesis embodiment in individuals with amputation. …”
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    From rubber hands to neuroprosthetics: Neural correlates of embodiment
  15. 8955
    “…Additionally, we discuss how the future of AI in dermatology might evolve and the emerging paradigm of large language, and multi-modal models to emphasize the importance of developing responsible, fair, and equitable models in dermatology.…”
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    Principles, applications, and future of artificial intelligence in dermatology
  16. 8956
    “…AI, with its ability to mimic human intelligence, presents a paradigm shift in surgical practices. The review critically analyzes a broad range of research, encompassing machine learning, deep learning, natural language processing, and their diverse applications in preoperative planning, surgical simulation, intraoperative guidance, and postoperative analysis. …”
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    Advancements and Challenges in the Application of Artificial Intelligence in Surgical Arena: A Literature Review
  17. 8957
    por Sahni, Vaibhav, Van Dyke, Thomas E.
    Publicado 2023
    “…The discovery of specialized pro-resolving mediators (SPMs) resulted in a paradigm shift in our understanding of disease etiopathology. …”
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    Immunomodulation of periodontitis with SPMs
  18. 8958
    “…Synthetic biology enabling the genetically reprograming of biological systems offers a new paradigm. It has achieved remarkable progresses in cell reprogramming, engineering designer cells for diverse applications. …”
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    Engineering the next generation of theranostic biomaterials with synthetic biology
  19. 8959
    “…Nonetheless, there are encouraging results and ongoing experiments that instill hope for potential paradigm shifts in HNSCC therapy.…”
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    Head and Neck Squamous Cell Carcinoma Vaccine: Current Landscape and Perspectives
  20. 8960
    “…Using a group walking paradigm, participants were instructed to synchronize with a metronome while listening to the sounds of 8 virtual partners. …”
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    You, me, and us: Maintaining self-other distinction enhances coordination, agency, and affect
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