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9041“…The list of transcript targets governed by a single miRNA provide a molecular paradigm applicable for therapeutic intervention. Indeed, reports have shown that specific manipulation of a miRNA in cell or animal models can significantly alter phenotypes linked with neurological disease. …”
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9042“…Finally, using a dual-task paradigm, we found that reducing attentional resources allocated to the moving target causes an increase in the perceived shift of the deviation point of the trajectory. …”
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9043“…Studies on both rats and mice indicate that histamine H3 receptor antagonists decrease alcohol drinking in several models, like operant alcohol administration and drinking in the dark paradigm. Alcohol-induced place preference is also affected by these drugs. …”
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9044“…To investigate how the visual system processes threatening actions, we employed a visual search paradigm with threatening boxer targets among emotionally-neutral walker distractors, and vice versa. …”
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9045“…Following priming, an automatic imitation paradigm was used to acquire an index of imitation. …”
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9046“…From the results, only with 10 minutes practice, the proposed paradigm of gestural-based control can achieve a performance of completing about six tasks per minute, which is in the same level of the RC-based method.…”
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9047“…Finally, we will argue that this paradigm is now challenged by the findings of a large randomized controlled trial in septic children. …”
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9048“…Studies on members of the crow family using the “Aesop's Fable” paradigm have revealed remarkable abilities in these birds, and suggested a mechanism by which associative learning and folk physics may interact when learning new problems. …”
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9049por Lamba, Gurpreet, Ambrale, Samir, Lee, Byung, Gupta, Ridhi, Rafiyath, Shamudheen M, Liu, Delong“…GIST research and clinical care now represent a paradigm of translating discoveries in the molecular pathogenesis of cancer into highly effective targeted therapies that selectively inhibit etiologic “driver” pathways, leading to dramatically improved clinical outcomes. …”
Publicado 2012
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9050por Bourgeois-Gironde, Sacha“…Such long-term profitability of short-sighted behavior cannot be evidenced when using a self-control paradigm (one which contrasts in a binary way sooner smaller and later larger payoffs) but becomes apparent when ecological patch-paradigms (replicating economic situations in which the main trade-off consists in staying on a food patch or leaving for another patch) are implemented. …”
Publicado 2012
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9051“…Here we provide experimental confirmation of this hypothesis using a classical paradigm known to create cognitive dissonance. Results of our experiment reveal that the exposure to Mozart's music exerted a strongly positive influence upon the performance of young children and served as basis by which they were enabled to reconcile the cognitive dissonance.…”
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9052“…To address this issue, we used a modified attentional blink (AB) paradigm in which masked (Experiment 1) or unmasked (Experiment 2) emotional faces (fearful or neutral) were presented before the AB sequence. …”
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9053por Wijlemans, J.W., Bartels, L.W., Deckers, R., Ries, M., Mali, W.P.Th.M., Moonen, C.T.W., van den Bosch, M.A.A.J.“…Recent decades have seen a paradigm shift in the treatment of liver tumours from invasive surgical procedures to minimally invasive image-guided ablation techniques. …”
Publicado 2012
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9054“…Quantum-dot cellular automata are an interesting nanoscale computing paradigm. The introduction of the ternary quantum-dot cell enabled ternary computing, and with the recent development of a ternary functionally complete set of elementary logic primitives and the ternary memorizing cell design of complex processing structures is becoming feasible. …”
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9055“…Personalized medicine is referred to as the ability to segment heterogeneous subsets of patients whose response to a therapeutic intervention within each subset is homogeneous. This new paradigm in healthcare is beginning to affect both research and clinical practice. …”
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9056“…Traditional concepts applied in clinical trials for the development of chemotherapeutic agents may be inadequate for immunotherapies and a new paradigm is emerging. It is possible that organized efforts and funding will accelerate the development of therapeutically effective cancer vaccines. …”
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9057por Prather, Richard W.“…In current study participants learn arithmetic principles via an implicit learning paradigm. Participants learn not by solving arithmetic equations, but through viewing and evaluating example equations, similar to the implicit learning of artificial grammars. …”
Publicado 2012
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9058por Schrobsdorff, Hecke, Ihrke, Matthias, Behrendt, Jörg, Hasselhorn, Marcus, Herrmann, J. Michael“…From the necessity of quantifying the experimental paradigms, we conclude that the specificity of the experimental paradigm must be taken into account when predicting the nature of the NP effect.…”
Publicado 2012
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9059“…We discuss the potential evolution of highly active anti-HER2 therapy (HAAHT) as an optimal treatment paradigm for HER2+ breast cancer. Additionally, we review lessons learned from the evolution of HAART for HIV treatment.…”
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9060por Day, Michael J., Breitschwerdt, Edward, Cleaveland, Sarah, Karkare, Umesh, Khanna, Chand, Kirpensteijn, Jolle, Kuiken, Thijs, Lappin, Michael R., McQuiston, Jennifer, Mumford, Elizabeth, Myers, Tanya, Palatnik-de-Sousa, Clarisa B., Rubin, Carol, Takashima, Gregg, Thiermann, Alex“…The One Health paradigm for global health recognizes that most new human infectious diseases will emerge from animal reservoirs. …”
Publicado 2012
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