“…BACKGROUND: The large increase in the size of patent collections has led to the need of efficient search strategies. …”
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“…Exploring the chemical and biological space covered by patent applications is crucial in early-stage medicinal chemistry activities. …”
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“…The aim of this study was to evaluate the effect of timing of surgical closure of patent ductus arteriosus (PDA) on ventilatory, hemodynamic, and nutritional status of preterm infants. …”
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“…BACKGROUND: Chorioamnionitis has recently been reported as a risk factor for various neonatal diseases, including cerebral palsy, bronchopulmonary dysplasia, and necrotizing enterocolitis, but its effect on patent ductus arteriosus (PDA) is unclear. We performed a systematic review and meta-analysis to evaluate the effect of chorioamnionitis on PDA. …”
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“…Advances in molecular biology and pharmacology aided in better understanding of breast cancer, enabling the design of smarter therapeutics able to target cancer and respond to its microenvironment efficiently. Patents and research papers investigating diagnosis and treatment strategies for breast cancer using novel technologies have been surveyed for the past 15 years. …”
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“…BACKGROUND: This paper aims to identify the key fields and their key technical points of oncology by patent analysis. METHODOLOGY/PRINCIPAL FINDINGS: Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. …”
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“…INTRODUCTION: A 3-year-old child, weighing 8 kg, presented with patent ductus arteriosus (PDA) and interrupted inferior vena cava (IVC). …”
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“…We describe the development of a chemical entity recognition system and its application in the CHEMDNER-patent track of BioCreative 2015. This community challenge includes a Chemical Entity Mention in Patents (CEMP) recognition task and a Chemical Passage Detection (CPD) classification task. …”
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“…The present case report describes the diagnostic procedures, surgical treatment and follow-up of the patent NPD in a 53-year-old female patient suffering from maxillary pain caused by a patent NPD.…”
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“…Exploratory studies can be carried using knowledge of the patent/IP landscape for synthetic biology and metabolic engineering. …”
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“…The database presented in this paper unveils the geography of historical patents granted by the United States Patent and Trademark Office (USPTO) from 1836 to 1975. …”
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“…Soon after, Turing caused an uproar when it announced that it would raise the price per tablet of Daraprim from [Formula: see text] , a 5500% price hike for a drug that has been on the market for over 60 years and off patent since the 1970s. Old, off-patent drugs are becoming increasingly expensive; Daraprim is the archetypal example. …”
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“…Here, we investigated where research activities are focused with respect to Wnt signaling modulators by searching the United States Patent and Trade Office (USPTO) for patents and patent applications related to Wnt modulators and compared this to clinical trials focusing on Wnt modulation. …”
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“…BACKGROUND: Percutaneous transcatheter closure (PTC) of patent foramen ovale (PFO) is implicated in cryptogenic stroke, transitional ischemic attack (TIA) and treatment of a migraine. …”
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“…Patent foramen ovale (PFO) is a remnant of fetal circulation commonly found in healthy population. …”
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“…The extension of intellectual property rights into the realm of biology has emerged as an increasing focus of controversy in relation to science,(2) biodiversity,(3) agriculture,(4) health,(5) development,(6) human rights(7) and trade.(8) This paper presents the results of a review of international trends in activity for patent protection between 1990-2000 and provisional data to 2004 and 2005 from over 70 national patent offices, four regional patent offices and the World Intellectual Property Organisation (WIPO) using the European Patent Office esp@cenet worldwide database.(9) The review employed patent publication counts as an indicator of activity for traditional medicines, pharmaceuticals, agriculture, and biotechnology. …”
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