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8261por Larsen, Magnus, Bartnes, Kristian, Tsai, Thomas T., Eagle, Kim A., Evangelista, Arturo, Nienaber, Christoph A., Suzuki, Toru, Fattori, Rossella, Froehlich, James B., Hutchison, Stuart, Sundt, Thoralf M., Januzzi, James L., Isselbacher, Eric M., Montgomery, Daniel G., Myrmel, Truls“…At the preoperative imaging, 414 (79.3%) patients had patent false lumens, 84 (16.1%) had partial thrombosis of the false lumen, and 24 (4.6%) had complete thrombosis of the false lumen. …”
Publicado 2013
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8262por Lexchin, Joel“…DATA SOURCES: Annual reports of the Therapeutic Products Directorate and the Biologic and Genetic Therapies Directorate; evaluations of therapeutic innovation from the Patented Medicine Prices Review Board and Prescrire International; MedEffect Canada website. …”
Publicado 2014
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8263por Rosenborg, Staffan, Nordström, Annica, Almquist, Tora, Wennberg, Lars, Bárány, Peter“…Since the expiration of the patent for Prograf(®), generic preparations have been approved in Europe as bioequivalence has been shown in healthy volunteers. …”
Publicado 2014
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8264“…We will search electronic databases and the grey literature using a predefined search strategy to identify randomised and non-randomised studies, technical reports and patents. Searches will not be restricted by language or date and will be expanded through contact with authors and experts, and by following up reference lists and citations. …”
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8265por Harno, Erika, Cottrell, Elizabeth C., Yu, Alice, DeSchoolmeester, Joanne, Gutierrez, Pablo Morentin, Denn, Mark, Swales, John G., Goldberg, Fred W., Bohlooly-Y, Mohammad, Andersén, Harriet, Wild, Martin J., Turnbull, Andrew V., Leighton, Brendan, White, Anne“…We then found that administration of compound C to male global 11β-HSD1 knockout mice elicited improvements in metabolic parameters, suggesting “off-target” mechanisms. Based on the patent literature, we synthesized another 11β-HSD1 inhibitor (MK-0916) from a different chemical series and showed that it too had similar off-target body weight and food intake effects at high doses. …”
Publicado 2013
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8266por Deininger, Maurilio Onofre, Moreira, Luiz Felipe Pinho, Dallan, Luiz Alberto Oliveira, de Oliveira, Orlando Gomes, Magalhães, Daniel Marcelo Silva, Coelho, José Reinaldo de Moura, Deininger, Eugênia di Giuseppe, Lopes, Norland de Souza, Queiroga, Ricardo Wanderley, Belmont, Elizabeth Ferreira“…Coronary CT angiography in 96 re-evaluated patients showed that all ITAs, right or left, used in situ for the left anterior descending were patent. There were no deaths in either group. CONCLUSION: Coronary artery bypass grafting surgery involving anastomosis of the anteroaortic right internal thoracic artery to the left anterior descending artery has an outcome similar to that obtained using the left internal thoracic artery for the same coronary site.…”
Publicado 2014
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8267por Wang, Changsong, Guo, Libo, Chi, Chunjie, Wang, Xiaoyang, Guo, Lei, Wang, Weiwei, Zhao, Nana, Wang, Yibo, Zhang, Zhaodi, Li, Enyou“…The combined results of available ventilation modes were not significantly different in regard to the incidences of patent ductus arteriosus and intraventricular hemorrhage. …”
Publicado 2015
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8268por Li, Hongliang, Wang, Xueding, Zhou, Yafang, Ni, Guanzhong, Su, Qibiao, Chen, Ziyi, Chen, Zhuojia, Li, Jiali, Chen, Xinmeng, Hou, Xiangyu, Xie, Wen, Xin, Shuang, Zhou, Liemin, Huang, Min“…However, the VPA Css in patents who gained weight were not significantly different from those who did not gain weight (p = 0.121). …”
Publicado 2015
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8269por Hyun, Chul Woong, Han, Eun Young, Im, Sang Hee, Choi, Jay Chol, Kim, Bo Ryun, Yoon, Ho Min, Lee, Yong Ki“…METHODS: Fifty-three subacute stroke patents were enrolled. Ambulatory function was assessed by gait speed and endurance. …”
Publicado 2015
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8270por Bittar, Joely FF, Bassi, Paula B., Moura, Dênia M., Garcia, Guilherme C., Martins-Filho, Olindo Assis, Vasconcelos, André B., Costa-Silva, Matheus F., Barbosa, Cristiano P., Araújo, Márcio SS, Bittar, Eustáquio R.“…CONCLUSIONS: The T. vivax infection in Zebu bulls from CSAI caused patent parasitemia, induced a febrile state, promoted reduction in the libido and increased the ejaculate volume. …”
Publicado 2015
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8271por Won, Hoyoun, Her, Ae-Young, Kim, Byeong-Keuk, Kim, Yong Hoon, Shin, Dong-Ho, Kim, Jung-Sun, Ko, Young-Guk, Choi, Donghoon, Kwon, Hyuck Moon, Jang, Yangsoo, Hong, Myeong-Ki“…RESULTS: Major adverse events occurred in 5 patients (5.6%) of the PCI group and in 17 patents (19.5%) of the OMT group (p=0.015). There were no significant differences between the PCI group and the OMT group in cardiac death [hazard ratio (HR) for the PCI group 0.454; 95% confidence interval (CI) 0.041–5.019, p=0.520], myocardial infarction (HR 0.399; 95% CI 0.039–4.050, p=0.437), or stroke (HR 0.919; 95% CI 0.057–14.709, p=0.952). …”
Publicado 2016
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8272por Knake, Lindsey A., Ahuja, Monika, McDonald, Erin L., Ryckman, Kelli K., Weathers, Nancy, Burstain, Todd, Dagle, John M., Murray, Jeffrey C., Nadkarni, Prakash“…RESULTS: Discrepancy rates between the EHR extraction and the manual database were calculated for gestational age in weeks (2.6 %), birthweight (9.7 %), first white blood cell count (3.2 %), initial hemoglobin (11.9 %), peak total and direct bilirubin (11.4 % and 4.9 %), and patent ductus arteriosus (PDA) diagnosis (12.8 %). …”
Publicado 2016
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8273por Fontanelli Sulekova, Lucia, Gabrielli, Simona, De Angelis, Maurizio, Milardi, Giovanni L., Magnani, Carlo, Di Marco, Biancamaria, Taliani, Gloria, Cancrini, Gabriella“…CONCLUSIONS: We report of a case in whom microfilariae were detected in fine-needle aspirate of subcutaneous node, without evidence of microfilaraemia, and the infection failed to become fully patent. Therefore we confirm that complete development and fertilization of D. repens worms in human hosts may occur, at variance with what is commonly believed, that Dirofilaria worms cannot fully develop in humans. …”
Publicado 2016
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8274por Padula, William V., Larson, Richard A., Dusetzina, Stacie B., Apperley, Jane F., Hehlmann, Rudiger, Baccarani, Michele, Eigendorff, Ekkehard, Guilhot, Joelle, Guilhot, Francois, Hehlmann, Rudiger, Mahon, Francois-Xavier, Martinelli, Giovanni, Mayer, Jiri, Müller, Martin C., Niederwieser, Dietger, Saussele, Susanne, Schiffer, Charles A., Silver, Richard T., Simonsson, Bengt, Conti, Rena M.“…CONCLUSION: When imatinib loses patent protection and its price declines, its use will be the cost-effective initial treatment strategy for CML-CP.…”
Publicado 2016
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8275por Chapman, Kathryn, Adjei, Akosua, Baldrick, Paul, da Silva, Antonio, De Smet, Karen, DiCicco, Richard, Hong, Seung Suh, Jones, David, Leach, Michael W., McBlane, James, Ragan, Ian, Reddy, Praveen, Stewart, Donald I. H., Suitters, Amanda, Sims, Jennifer“…The first approved biosimilar medicines were small proteins, and more recently biosimilar versions of innovator monoclonal antibody (mAb) drugs have entered development as patents on these more complex proteins expire. In September 2013, the first biosimilar mAb, infliximab, was authorised in Europe. …”
Publicado 2016
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8276“…BACKGROUND: PDA(Patent ductus arteriosus) is a common and clinically important condition which is presented with a number of hemodynamic and respiratory problems such as intraventricular hemorrhage, pulmonary hemorrhage and necrotizing enterocolitis due to increased pulmonary blood flow and stealing from systemic circulation. …”
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8277por Arévalo-Herrera, Myriam, Vásquez-Jiménez, Juan M., Lopez-Perez, Mary, Vallejo, Andrés F., Amado-Garavito, Andrés B., Céspedes, Nora, Castellanos, Angélica, Molina, Karen, Trejos, Johanna, Oñate, José, Epstein, Judith E., Richie, Thomas L., Herrera, Sócrates“…All non-protected volunteers developed symptoms 8–13 days after CHMI with a mean pre-patent period of 12.8 days. No serious adverse events related to the immunizations were observed. …”
Publicado 2016
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8278por Sinha, Santosh Kumar, Mishra, Vikas, Singh, Karandeep, Asif, Mohammad, Sachan, Mohit, Kumar, Ashutosh, Jha, Mukesh Jitendra, Khanra, Dibbendhu, Singh, Avinash Kumar, Singh, Shravan, Razi, Mahamdula, Thakur, Ramesh, Pandey, Umeshwar, Varma, Chandra Mohan“…Twenty-one (75%) had severe mitral stenosis (MS) including severe tricuspid regurgitation (n = 13, 61%), ventricular septal defect (VSD, n = 3, 14%), complete endocardial cushion defect (ECD, n = 3, 14%), and mild to moderate mitral regurgitation (MR) (n = 2, 11%), moderate MS and moderate MR were found in four (16%) patients among complete bridge type of DOMV, while all patients with incomplete bridge type had severe MS and patent ductus arteriosus (PDA) as associated lesions. …”
Publicado 2016
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8279por Grady, Elliot Nicholas, MacDonald, Jacqueline, Liu, Linda, Richman, Alex, Yuan, Ze-Chun“…This review also includes detailed information in Additional files 1, 2, 3 for major known Paenibacillus species with their locations of isolation, genome sequencing projects, patents, and industrially significant compounds and enzymes. …”
Publicado 2016
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8280por Kundra, Pankaj, Garg, Rakesh, Patwa, Apeksh, Ahmed, Syed Moied, Ramkumar, Venkateswaran, Shah, Amit, Divatia, Jigeeshu Vasishtha, Shetty, Sumalatha Radhakrishna, Raveendra, Ubaradka S, Doctor, Jeson R, Pawar, Dilip K, Singaravelu, Ramesh, Das, Sabyasachi, Myatra, Sheila Nainan“…At times, maintaining a patent airway may become difficult either due to direct handling during initial airway management or due to surgical intervention. …”
Publicado 2016
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