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9421por Getaneh, Yimam, Ning, Feng, He, Qianxin, Rashid, Abdur, Kassa, Desta, Assefa, Yibeltal, Yi, Feng, Liao, Lingjie, Shao, Yiming“…A mortality jump of 9.25% was observed among patents initiating HAART in 2017, which coincided with political instability happened in the country. …”
Publicado 2022
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9422por Nir-Paz, Ran, Onallah, Hadil, Gellman, Yechiel N, Haze, Amir, Braunstein, Ron, Hazan, Ronen, Leandro, Clara, Barbosa, Raquel, Dordio, Helena, Wagner, Alexandra, Corte Real, Sofia V, Garcia, Miguel“….: Employee Miguel Garcia, n/a, IBV Innovation Bioventures Lda: Board Member|IBV Innovation Bioventures Lda: Ownership Interest|LX Bio Pharmaceuticals SA: Board Member|LX Bio Pharmaceuticals SA: Ownership Interest|TechnoPhage, SA: Board Member|TechnoPhage, SA: Author of several patent applications|TechnoPhage, SA: Ownership Interest.…”
Publicado 2022
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9423“…If efficacy is proved definitively, new patent-free vaccines could lower costs of worldwide SARS-CoV-2 vaccination campaigns significantly. …”
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9424por Youssef, David Edward, Averin, Konstantin, Richards, Susan, Sheppard, Catherine, Seaman, Cameron, Pietrosanu, Matthew, Bates, Angela“…At a six-month clinical assessment, all group 1 patients had patent devices and improved WHO FCs. CONCLUSION: This work presents a single center's experience with AFR and FASD implants in a heterogeneous group of fourteen pediatric patients with severe PH. …”
Publicado 2023
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9425“…IMAGE: [Image: see text] CONCLUSION(S): Portosystemic shunt placement in the form of TIPSS or DIPS insertion is an increasingly common and effective treatment for portal hypertension in patents with advanced liver disease at UHN. DISCLOSURE OF INTEREST: None Declared…”
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9426por Galvez, Carlos, Nizamuddin, Imran, Tuchman, Emily, Doukas, Peter, Reddy, Neha, Altman, Jessica K., Winter, Jane N., Gordon, Leo I., Barth, Dylan, Hodgins, Nicole, Pro, Barbara, Ma, Shuo, Dinner, Shira, Frankfurt, Olga, Mehta, Jayesh, Singhal, Seema, Adekola, Kehinde, Moreira, Jonathan, Tanna, Sajal D, Wehbe, Firas, Karmali, Reem“…Gordon:Zylem Biosciences: Patents & Royalties: Patents, No Royalties. Pro:Verastem Oncology: Research Funding. …”
Publicado 2020
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9427por Nadeem, Omar, Mo, Clifton C, Laubach, Jacob P., Bianchi, Giada, Redd, Robert, Barth, Peter, Bayliss, Trevor J., Sanchorawala, Vaishali, Shune, Leyla, Distaso, Alexandra, Dalton, Virginia, Sperling, Adam S, Amweg, Laura, McKenney, Mary, Colson, Kathleen, Millard, Ella L, Hou, Isabella, Savell, Alexandra, Masone, Kelly, Munshi, Nikhil C., Ghobrial, Irene M., Anderson, Kenneth, Richardson, Paul G.“…Sanchorawala:Takeda: Research Funding; Celgene: Research Funding; Prothena: Research Funding; Caelum: Research Funding; Oncopeptide: Research Funding; Regeneron: Other: advisory board; Caleum: Other: advisory board; Proclara: Other: advisory board; Abbvie: Other: advisory board; UpToDate: Patents & Royalties; Janssen: Research Funding. Munshi:BMS: Consultancy; OncoPep: Consultancy, Current equity holder in private company, Membership on an entity’s Board of Directors or advisory committees, Patents & Royalties; C4: Current equity holder in private company; Janssen: Consultancy; Adaptive: Consultancy; Legend: Consultancy; Amgen: Consultancy; AbbVie: Consultancy; Karyopharm: Consultancy; Takeda: Consultancy. …”
Publicado 2020
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9428por Mack, Andrew R, Bethel, Christopher, Marshall, Steven, Patel, Robin, Patel, Robin, van Duin, David, Fowler, Vance G, Rhoads, Daniel D, Jacobs, Michael, van den Akker, Focco, Six, David A, Moeck, Greg, Papp-Wallace, Krisztina M, Bonomo, Robert A“…DISCLOSURES: Robin Patel, MD, 1928 Diagnostics (Consultant)BioFire Diagnostics (Grant/Research Support)ContraFect Corporation (Grant/Research Support)Curetis (Consultant)Hylomorph AG (Grant/Research Support)IDSA (Other Financial or Material Support, Editor’s Stipend)Infectious Diseases Board Review Course (Other Financial or Material Support, Honoraria)Mammoth Biosciences (Consultant)NBME (Other Financial or Material Support, Honoraria)Netflix (Consultant)Next Gen Diagnostics (Consultant)PathoQuest (Consultant)PhAST (Consultant)Qvella (Consultant)Samsung (Other Financial or Material Support, Patent Royalties)Selux Diagnostics (Consultant)Shionogi & Co., Ltd. …”
Publicado 2021
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9429por Mack, Andrew R, Bethel, Christopher, Marshall, Steven, Patel, Robin, Patel, Robin, van Duin, David, Fowler, Vance G, Rhoads, Daniel D, Jacobs, Michael, van den Akker, Focco, Six, David A, Moeck, Greg, Papp-Wallace, Krisztina M, Bonomo, Robert A“…DISCLOSURES: Robin Patel, MD, 1928 Diagnostics (Consultant)BioFire Diagnostics (Grant/Research Support)ContraFect Corporation (Grant/Research Support)Curetis (Consultant)Hylomorph AG (Grant/Research Support)IDSA (Other Financial or Material Support, Editor’s Stipend)Infectious Diseases Board Review Course (Other Financial or Material Support, Honoraria)Mammoth Biosciences (Consultant)NBME (Other Financial or Material Support, Honoraria)Netflix (Consultant)Next Gen Diagnostics (Consultant)PathoQuest (Consultant)PhAST (Consultant)Qvella (Consultant)Samsung (Other Financial or Material Support, Patent Royalties)Selux Diagnostics (Consultant)Shionogi & Co., Ltd. …”
Publicado 2021
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9430por Gonzales-Luna, Anne J, Skinner, Andrew M, Alonso, Carolyn D, Cornely, Oliver A, Garey, Kevin W, Gerding, Dale N, Johnson, Stuart, Kahn, Stacy A, Kelly, Ciaran P, Kelly, Colleen R, Kociolek, Larry K, Kuijper, Ed J, Kuijper, Ed J, Louie, Thomas J, Riley, Thomas V, Sandora, Thomas J, Vehreschild, Maria, Wilcox, Mark H, Dubberke, Erik R“…Dr., Abbott: Honoraria|Abbvie: Advisor/Consultant|Actelion: Board Member|Al-Jazeera Pharmaceuticals: Honoraria|Allecra Therapeutics: Board Member|Amplyx: Advisor/Consultant|Amplyx: Grant/Research Support|Astellas: Honoraria|Basilea: Advisor/Consultant|Basilea: Grant/Research Support|Biocon: Advisor/Consultant|Biosys: Advisor/Consultant|BMBF: Grant/Research Support|Cidara: Advisor/Consultant|Cidara: Board Member|Cidara: Expert Testimony|Cidara: Grant/Research Support|CoRe Consulting: Stocks/Bonds|Da Volterra: Advisor/Consultant|DLR: Grant/Research Support|DZIF: Grant/Research Support|Entasis: Board Member|EU Directorate-General for Resarch and Innovation: Grant/Research Support|F2G: Grant/Research Support|German Patent and Trade Mark Office: German patent (DE 10 2021 113 007.7)|Gilead: Advisor/Consultant|Gilead: Grant/Research Support|Grupo Biotoscana/United Medical/Knight: Honoraria|Hikma: Honoraria|IQVIA: Board Member|Janssen: Board Member|Matinas: Advisor/Consultant|Matinas: Grant/Research Support|MedPace: Advisor/Consultant|MedPace: Grant/Research Support|MedScape: Honoraria|MedUpdate: Honoraria|Menarini: Advisor/Consultant|Merck/MSD: Grant/Research Support|Merck/MSD: Honoraria|Molecular Partners: Advisor/Consultant|MSG-ERC: Advisor/Consultant|Mundipharma: Grant/Research Support|Mylan: Honoraria|Noxxon: Advisor/Consultant|Octapharma: Advisor/Consultant|Octapharma: Grant/Research Support|Paratek: Board Member|Pardes: Advisor/Consultant|Pfizer: Grant/Research Support|Pfizer: Honoraria|Projektträger Jülich: Grant/Research Support|PSI: Advisor/Consultant|PSI: Board Member|Pulmocide: Board Member|Scynexis: Advisor/Consultant|Scynexis: Grant/Research Support|Seres: Advisor/Consultant|Shionogi: Board Member|Wiley (Blackwell): Editor-in-Chief, Mycoses Kevin W. …”
Publicado 2022
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9431“…Several studies showed significant therapeutic effects for the Chinese patent medicine Suxiao Jiuxin Pill (SJP) in MIRI, although the specific molecular mechanisms remain undefined. …”
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9432por Assefa, Dawit Getachew, Bedru, Ahmed, Zeleke, Eden Dagnachew, Negash, Solomon Emiru, Debela, Dejene Tolossa, Molla, Wondowsen, Mengistu, Nebiyu, Woldesenbet, Tigist Tekle, Bedane, Neway Fekede, Kajogoo, Violet Dismas, Atim, Mary Gorret, Manyazewal, Tsegahun“…Furthermore, grade 3 and 4 liver toxicity was more common in patents who have taken 9H, 1HP, and 6H. This may support the current recommended TPT regimen of 3HP, 3RH, and 6H.…”
Publicado 2023
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9433por Santini, Lorenzo, Duranti, Claudia, Palandri, Chiara, Giammarino, Lucrezia, Musumeci, Monica, Carlucci, Lucia, Capitani, Chiara, Colasurdo, Rossella, Recchia, Fabio, Cerbai, Elisabetta, Coppini, Raffaele, Arcangeli, Annarosa“…Based on our discovery that hERG1 resides in a macromolecular complex with the β1 subunit of integrin adhesion receptors only in tumors, and not in the heart, we generated (and patented WO2019/015936) a novel engineered, single chain, bispecific antibody in the format of a diabody (scDb-hERG1-β1). …”
Publicado 2023
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9434“…While academic-led clinical trials are occasionally conducted to test off-label uses of drugs with expired patents, this is relatively rare. In this work, we explored how a patient-centered online research platform could supplement traditional trials to create a richer understanding of medical products postmarket by efficiently aggregating structured patient-reported data. …”
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9435por Campbell, Suzy J., Stothard, J. Russell, O’Halloran, Faye, Sankey, Deborah, Durant, Timothy, Ombede, Dieudonné Eloundou, Chuinteu, Gwladys Djomkam, Webster, Bonnie L., Cunningham, Lucas, LaCourse, E. James, Tchuem-Tchuenté, Louis-Albert“…Material from snail and parasite species were characterised by DNA methods. RESULTS: Egg-patent prevalence of urogenital schistosomiasis was 8.7% at Barombi Mbo (all light-intensity infections) and 40.1% at Barombi Kotto (21.2% heavy-intensity infections). …”
Publicado 2017
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9436por Kociolek, Larry, Kelly, Ciaran P, Espinosa, Robyn, Budz, Maria, Balaji, Aakash, Ozer, Egon, Tanz, Robert, Chen, Xinhua, Gerding, Dale N“…Treatment/Prevention of C. difficile: Patent Holder, no license or royalties.…”
Publicado 2018
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9437por Saito, Makoto, Mansoor, Rashid, Kennon, Kalynn, Anvikar, Anupkumar R., Ashley, Elizabeth A., Chandramohan, Daniel, Cohee, Lauren M., D’Alessandro, Umberto, Genton, Blaise, Gilder, Mary Ellen, Juma, Elizabeth, Kalilani-Phiri, Linda, Kuepfer, Irene, Laufer, Miriam K., Lwin, Khin Maung, Meshnick, Steven R., Mosha, Dominic, Muehlenbachs, Atis, Mwapasa, Victor, Mwebaza, Norah, Nambozi, Michael, Ndiaye, Jean-Louis A., Nosten, François, Nyunt, Myaing, Ogutu, Bernhards, Parikh, Sunil, Paw, Moo Kho, Phyo, Aung Pyae, Pimanpanarak, Mupawjay, Piola, Patrice, Rijken, Marcus J., Sriprawat, Kanlaya, Tagbor, Harry K., Tarning, Joel, Tinto, Halidou, Valéa, Innocent, Valecha, Neena, White, Nicholas J., Wiladphaingern, Jacher, Stepniewska, Kasia, McGready, Rose, Guérin, Philippe J.“…METHODS: A systematic review and one-stage IPD meta-analysis of studies assessing the efficacy of artemisinin-based and quinine-based treatments for patent microscopic uncomplicated falciparum malaria infection (hereinafter uncomplicated falciparum malaria) in pregnancy was conducted. …”
Publicado 2020
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9438por Berkhout, Robbert P, Keijser, Remco, Repping, Sjoerd, Lambalk, Cornelis B, Afink, Gijs B, Mastenbroek, Sebastiaan, Hamer, Geert“…R.P.B., G.H. and S.M. have a patent on the use of hsa-miR-320a in assisted reproduction treatments pending. …”
Publicado 2020
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9439por Nie, Fujiao, Yan, Jiazhao, Ling, Yanjun, Liu, Zhengrong, Fu, Chaojun, Li, Xiang, Qin, Yuhui“…Since apoptosis of retinal microvascular pericytes (RMPs) is the early characteristic of DR, this study aimed to reveal the mechanism of Shuangdan Mingmu (SDMM) capsule, a Chinese patent medicine, on oxidative stress-induced apoptosis of pericytes implicated with poly (ADP-ribose) polymerase (PARP) / glyceraldehyde 3-phosphate dehydrogenase (GAPDH) pathway. …”
Publicado 2021
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9440por Wierdsma, Nicolette J., Kruizenga, Hinke M., Konings, Lotte AML., Krebbers, Daphne, Jorissen, Jolein RMC., Joosten, Marie-Helene I., van Aken, Loes H., Tan, Flora M., van Bodegraven, Ad A., Soeters, Maarten R., Weijs, Peter JM.“…Serious acute weight loss (>5 kg) was showed in 22% of the patents during the hospital stay; most of these patients (85%) were admitted to the ICU at any point in time. …”
Publicado 2021
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