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1021“…In this article we propose a new approach to pricing for patent-protected (on-patent) pharmaceuticals. We describe and define limit pricing as a method for drug companies to maximize revenue for their investment by offering budget-neutral pricing to encourage early adoption by payers. …”
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1022por den Toom, Marjolein L., Meiling, Agnes E., Thomas, Rachel E., Leegwater, Peter A. J., Heuven, Henri C. M.“…BACKGROUND: Patent ductus arteriosus (PDA) is one of the most common congenital heart defects in dogs and is considered to be a complex, polygenic threshold trait for which a female sex predisposition has been described. …”
Publicado 2016
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1023“…Cleaning and analyzing the publicly available data from the United States Patent and Trademark Office we illustrate that Central and Eastern European patents made in international co-operations with partners outside the region receive more citations than those Central and Eastern European patents that lack international co-operation. …”
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1024por dos REIS, José Maciel Caldas, PINHEIRO, Maurício Fortuna, OTI, André Takashi, FEITOSA-JUNIOR, Denilson José Silva, PANTOJA, Mauro de Souza, BARROS, Rui Sérgio Monteiro“…RESULTS: This search haven't found any deposit at the brazilian patents website (INPI) in this period; US Patent &Trademark Office had registered 60 titles in patents and the European Patent Office (EPO) showed 10 documents on the issue. …”
Publicado 2016
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1025“…Through an empirical investigation of patent data in the biotechnology industry from 1976 to 2003, we find that a technology’s internal (i.e., density and diversity) ecological characteristics have a positive effect on its growth rate. …”
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1026“…BACKGROUND: Qianggu Capsule, a Chinese patent medicine, has been widely applied in the clinical practice of primary osteoporosis (POP) in recent years. …”
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1027por Senger, Stefan“…BACKGROUND: Patents are an important source of information for effective decision making in drug discovery. …”
Publicado 2017
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1028“…BACKGROUND: The association between patent foramen ovale (PFO) and migraine with aura (MA) is well established. …”
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1029“…INTRODUCTION: Patent vitellointestinal duct occurs in about 2% of the population which unusually leads to small intestinal obstruction associated with high morbidity and mortality. …”
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1030A global comparison of the cost of patented cancer drugs in relation to global differences in wealthpor Goldstein, Daniel A., Clark, Jonathon, Tu, Yifan, Zhang, Jie, Fang, Fenqi, Goldstein, Robert, Stemmer, Salomon M., Rosenbaum, EliEnlace del recurso
Publicado 2017
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1031
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1032“…BACKGROUND: It has been suggested that there is an increase in aortic regurgitation (AR) in the short and medium term after percutaneous closure of patent foramen ovale (PFO). The aim of this study is to determine the long-term effect of percutaneous closure of PFO on the prevalence of AR. …”
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1033“…Technology diffusion and interest diffusion are measured by the volume of patent citations and web search traffic, respectively. …”
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1034“…In this article we have presented an adult patient with biventricular myocardial NC cardiomyopathy accompanied by severe valvular pulmonary stenosis and patent foramen ovale.…”
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1036“…A large volume of patent data, 15,422 patent filings citing Chinese pharmaceutical patents, 28,075 citing U.S. patents, and 6064 citing both Chinese and U.S. patents during 2014–2015, were retrieved from the world patent database, Derwent Innovation Index. …”
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1038“…The aim of this study was to investigate the effects of prophylactic oral ibuprofen on the closure rate of patent ductus arteriosus (PDA). This was a retrospective study and data on infants born before 36 weeks were collected. …”
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1039por Nguyen, Hieu Lan, Phan, Quang Tan, Doan, Dung Duc, Dinh, Linh Huynh, Tran, Hieu Ba, Sharmin, Saima, Thottian, Julian Johny, Won, Hoyoun, Lee, Wang Soo, Shin, Seung Yong, Nguyen, Truong Quang, Kim, Sang Wook“…OBJECTIVES: To assess the safety and efficacy of percutaneous closure of perimembranous ventricular septal defect (PmVSD) using patent ductus arteriosus (PDA) occluders. BACKGROUND: Widespread use of conventional PmVSD closure devices has been limited by unacceptable high rate of complete heart block (CHB). …”
Publicado 2018
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1040por Flint, Robert B., ter Heine, Rob, Spaans, Edwin, Burger, David M., de Klerk, Johan C. A., Allegaert, Karel, Knibbe, Catherijne A. J., Simons, Sinno H. P.“…PURPOSE: Ibuprofen is the drug of choice for treatment of patent ductus arteriosus (PDA). There is accumulating evidence that current ibuprofen-dosing regimens for PDA treatment are inadequate. …”
Publicado 2018
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