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2701por Kim, Soo-Hong, Cho, Yong-Hoon, Kim, Hae-Young, Lee, Narae, Han, Young Mi, Byun, Shin Yun“…If peritonitis due to gastrointestinal perforation occurs, abdominal contamination may spread through a patent processus vaginalis in an infant, which may lead to pyocele. …”
Publicado 2021
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2702por Bernstein, Jeremy“…In March 1905, at approximately eight week intervals, the Editor of the noted German physics journal, Annalen der Physik, received three hand-written manuscripts from a relatively unknown patent examiner in Bern, Switzerland. This patent examiner was the twenty-six year old Albert Einstein and the three papers would set the agenda for twentieth century physics. …”
Publicado 2006
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2703“…Finding new therapeutic indications for already established drug substances is known as redirecting, repositioning, reprofiling, or repurposing of drugs. Off-patent and on-patent drugs can be screened for additional targets and new indications thus bringing them to clinical trials at a faster pace. …”
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2704por Moustafa, Giannis A., Kolokythas, Argyrios, Charitakis, Konstantinos, Avgerinos, Dimitrios V.“…Nowadays, a large variety of heart diseases are managed with transcatheter techniques, such as patent foramen ovale, atrial and ventricular septal defects, valve stenosis, patent ductus arteriosus, aortic coarctation, pulmonary artery and vein stenosis and arteriovenous malformations. …”
Publicado 2016
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2705“…M4K Pharma was incorporated to launch an open science drug discovery program that relies on regulatory exclusivity as its primary intellectual property and commercial asset, in lieu of patents.In many cases and in key markets, using regulatory exclusivity can provide equivalent commercial protection to patents, while also being compatible with open science. …”
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2706“…A 24-day-old apparently asymptomatic neonate was found to have complete transposition of great arteries with small patent ductus arteriosus and restrictive patent foramen ovale. …”
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2707por Tatekawa, Yukihiro“…When the inguinal canal was opened, a patent processus vaginalis was observed and the testis was found inside the abdominal cavity. …”
Publicado 2020
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2708“…The patient underwent successful transcatheter patent foramen ovale closure with a 25-mm Gore Cardioform septal occluder device with immediate and sustained improvement in hypoxia.…”
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2709por Guerroum, Hind, Rami, Amal, Kassimi, Mariam, Habi, Jihane, Imane, Rahmouni, Chikhaoui, Nabil, Rouibaa, Fadwa, Mahi, Mohamed“…The procedure was difficult and the placement of a long-term pancreatic stent during the ERCP was impossible, thus a surgical pancreatico-jejunostomy was proposed as a treatment of an ansa pancreatica with a non-patent major papilla.…”
Publicado 2020
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2710por Aitzetmüller, Matthias M., Klietz, Marie-Luise, Dermietzel, Alexander F., Hirsch, Tobias, Kückelhaus, Maximilian“…This review is based on a PubMed and Google Scholar database search, including case reports, case series, clinical and preclinical trials, as well as patents. Past, recent approaches, ongoing patents, as well as eight specific systems for robotic-assisted microsurgery and their potential to be translated into a clinical routine, are described. …”
Publicado 2022
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2711por Jungnickel, Kat“…This involves stitching data, theory and fabric into inventions described in patents and analysing them as three-dimensional arguments. …”
Publicado 2022
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2712por Roquini, Vinícius, Mengarda, Ana C., Cajas, Rayssa A., Martins-da-Silva, Milene F., Godoy-Silva, Julia, Santos, Gustavo A., Espírito-Santo, Maria Cristina C., Pavani, Thais F. A., Melo, Vanusa A., Salvadori, Maria C., Teixeira, Fernanda S., Rando, Daniela G. G., de Moraes, Josué“…In patent infection, NFZ achieved a high reduction in the number of eggs (~80%), but the drug caused a low reduction in the egg burden of animals with prepatent infection. …”
Publicado 2023
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2713por Sanati, Hamidreza, Zahedmehr, Ali, Firouzi, Ata, Salehi, Negar, Maadani, Mohsen, Shakerian, Farshad, Kiani, Reza, Golnari, Pedram, Parchami-Ghazaee, Sepideh, Peighambari, Mohammadmehdi“…OBJECTIVES: The present study is aimed to measure the TFC in the coronary arteries of UA/NSTEMI patients to find abnormalities in diseased or patent vessels and compare with the normal values. …”
Publicado 2013
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2714“…ABSTRACT: Before the first generic version of a drug is marketed, patent litigation often occurs. The process begins when generic manufacturers notify the US Food and Drug Administration (FDA) of their intent to market a generic copy of a brand‐name drug protected by patents, which they allege to be invalid or not infringed (called a Paragraph IV certification). …”
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2715por Silva, Roberto Rocha e, Goncharov, Maxim, de Freitas, Fabiane Letícia, Mejia, Omar Asdrúbal Vilca“…They all underwent midterm multidetector computed tomography after surgery with the association of at least one patent LITA and one patent RA graft. RESULTS: Twelve patients (46%) are alive with no angina symptoms. …”
Publicado 2023
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2716por Pereira, Mariana Rangel, Mercaldi, Gustavo Fernando, Maester, Thaís Carvalho, Balan, Andrea, de Macedo Lemos, Eliana Gertrudes“…Phylogenetic studies showed that the enzyme belongs to family V of bacterial lipolytic enzymes and has sequence and structural similarities with an aryl-esterase from Pseudomonas fluorescens and a patented Anti-Kazlauskas lipase (patent number US20050153404). …”
Publicado 2015
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2717“…We use textual content from patent sets in 27 domains to find the influence of interactions on improvement rates. …”
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2718“…Studying 24 million research articles and 3.9 million US patents, we find a substantial impact advantage of teamwork over solo work. …”
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2719por Isawi, Israa H., Morales, Paula, Sotudeh, Noori, Hurst, Dow P., Lynch, Diane L., Reggio, Patricia H.“…This model permitted the identification of unique GPR6 structural features and the exploration of the GPR6 binding crevice. A subset of patented pyrazine analogs were docked in the resultant GPR6 inactive state model to validate the model, rationalize the structure-activity relationships from the reported patents and identify the key residues in the binding crevice for ligand recognition. …”
Publicado 2020
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2720por Li, Zhiyong, Li, Caifeng, Zhang, Xiaobo, Tang, Shihuan, Yang, Hongjun, Cui, Xiuming, Huang, Luqi“…We investigated Chinese patent medicines (CPMs) declared as ethnomedicine on the drug instructions and identified 28 Dai patent medicines (DPMs) and 73 Yi patent medicines (YPMs) that were approved for clinical use in China. …”
Publicado 2020
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