“…This review mainly focuses on the recent advances in patented approaches for chikungunya vaccine development and the forthcoming challenges.…”
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“…There continues to be a reluctance to close the patent ductus arteriosus (PDA) in premature infants. …”
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“…This a case of a patient with acute limb ischaemia in whom thorough transesophageal echocardiography (TEE) evaluation depicted a patent foramen ovale and allowed for the detection of a large thrombus arising from an atherosclerotic calcified plaque in the thoracic aorta. …”
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“…The most common of these is patent foramen ovale (PFO). Once this is identified, closure of the PFO can lead to resolution of hypoxia.…”
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“…Substitute drugs and notable patent expirations between 2004 and 2011 were obtained via pharmacist review. …”
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“…[Image: see text] [Image: see text] [Image: see text] [Image: see text] DISCLOSURES: Ritu Banerjee, MD, PhD, Accelerate Diagnostics: Grant/Research Support; BioFire: Research Grant; Biomerieux: Research Grant; Roche: Research Grant Robin Patel, MD, ASM and IDSA: Other Financial or Material Support, Travel reimbursement, editor’s stipends; CD Diagnostics, Merck, Hutchison Biofilm Medical Solutions, Accelerate Diagnostics, ContraFect, TenNor Therapeutics Limited, Shionogi: Grant/Research Support; Curetis, Specific Technologies, NextGen Diagnostics, PathoQuest, Qvella: Consultant; NBME, Up-to-Date, the Infectious Diseases Board Review Course: Honorarium recipient, Other Financial or Material Support; Patent on Bordetella pertussis/parapertussis PCR issued, a patent on a device/method for sonication with royalties paid by Samsung to Mayo Clinic, and a patent on an anti-biofilm substance issued: Other Financial or Material Support, Patents.…”
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“…KEY MESSAGES: Nocturnal non-dipping patterns of blood pressure were associated with cryptogenic ischemic stroke except in participants with a patent foramen ovale and in those without hypertension by any definition, which may indicate differing pathophysiology underlying cryptogenic ischemic stroke in patients with and without a patent foramen ovale. …”
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“…METHODS AND RESULTS: Using the nationwide Danish registries, we identified individuals diagnosed with isolated ventricular septal defect, atrial septal defect, patent ductus arteriosus, or pulmonary stenosis during 1977 to 2015, who were alive at 5 years of age. …”
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“…These are developed after patent expiration of innovator biopharmaceuticals and are submitted for separate marketing approval. …”
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“…Aortic stenosis and mitral regurgitation, patent foramen ovale, interatrial septal defect, atrial fibrillation and perivalvular leak, are now amenable to percutaneous treatment. …”
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“…An echocardiogram showed normal cardiac anatomy, patent ductus arteriosus, and retrograde flow in the descending aorta. …”
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“…It also has been shown an association with atopic disease and cardiovascular disease, especially ischemic stroke and patent foramen ovale (PFO).…”
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“…The canal of Nuck is analogous to a patent processus vaginalis in a male, which normally loses its communication to the peritoneal cavity within the first year of life. …”
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“…Cardiac abnormalities are found in a third of individuals with this condition and usually consist of isolated septal defects or patent ductus arteriosus, although more complex congenital lesions have been described. …”
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“…We describe spontaneous cerebrospinal fluid (CSF) otorrhea through a patent tympanomeningeal (Hyrtl) fissure presenting as recurrent serous otitis media. …”
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“…Agitated saline contrast bubble study showed evidence of a right to left intracardiac shunt, probably secondary to a patent foramen ovale. Results of a transesophageal echocardiogram suggested the possibility of an anomalous venous circulation and eventually identified as anomalous left-sided superior vena cava with cardiac magnetic resonance imaging.…”
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“…Infection occasionally occurs in patients with congenital patent urachus. Here, we report a patient with infection of a previously closed urachal tract presenting as an abdominal mass. …”
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“…Several relevant problems and issues were addressed and perspectives of scientific researches from urology and pathology as well as those of managers from the pharmaceutical industry and the field of patent law were discussed with an interdisciplinary audience.…”
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“…We present a rare case of the surgical management of bilateral LVMs arising at the junction of the brachiocephalic and internal jugular veins in a patient with a patent foramen ovale, identifying the source of previously unexplained paradoxical cerebrovascular accidents.…”
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“…Albert Einstein re-wrote the textbooks of science in 1905: physics since has been little more than a series of footnotes to the theories of a 26-year-old patent-office clerk. Einstein's science and emotional life come together in this vivid portrait of a rebellious and contradictory figure, a pacifist whose legendary equation E=mc2 opened scientists' eyes to the terrible power within every atom. …”
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