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  1. 3241
    “…A similar opportunity presents years later with the completion of the full patent exclusivity period of many biologics. However, the ending of patent exclusivity, although enables more market competition, does not guarantee market penetration. …”
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    A narrative review of biosimilars: a continued journey from the scientific evidence to practice implementation
  2. 3242
    “…DISCLOSURES: Ofer Levy, MD, PhD, Avidea (Other Financial or Material Support, collaboration)Exicure (Other Financial or Material Support, collaboration)Multiple patents (Other Financial or Material Support, I am a named inventor on patents related to vaccine adjuvants)…”
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    349. Hardware-Associated Multidrug-resistant Pseudomonas aeruginosa Meningitis Treated with Ceftolozane-Tazobactam
  3. 3243
    “…The diagnoses were ventricular septal defect, patent ductus arteriosus, and definite interruption of the aortic arch. …”
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    Isolated interrupted aortic arch in an adult: A case report
  4. 3244
    “…The first patient died from pneumonia after 3 weeks in the intensive care unit; at that time, the foot was viable with triphasic flow in the distal posterior tibial artery and the AVF was patent. The second and third patients are doing well, they can walk without any problems, and the tibial arteries and AFV were patent on duplex ultrasound after 6 months. …”
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    Distal arteriovenous fistula to preserve patency in COVID-19–associated acute limb ischemia
  5. 3245
    “…Pelargonium graveolens plant named Narmada was discovered by Kulkarni R.N et al. (Patent ID, USPP12425P2) and a formulation comprising thymol obtained from Trachyspermum is useful in the treatment of drug-resistant bacterial infections (Patent ID, US6824795B2). …”
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    The Chemical Composition and Anti-mycobacterial Activities of Trachyspermum copticum and Pelargonium graveolens Essential Oils
  6. 3246
    por Wang, Chunying, Shi, Yunlong, Ji, Jianwei
    Publicado 2021
    “…OBJECTIVES: The paper uses block matching method combined with echocardiography to explore the value of N-terminal pro-brain natriuretic peptide (NT-proBNP) in predicting symptomatic patent ductus arteriosus (PDA) in preterm infants. …”
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    Application of block matching method-based Echocardiography combined with serum NT-PROBNP level detection in the early prediction of PDA in premature infants
  7. 3247
    “…We will design and implement this clinical trial using the patent of ‘a radiotherapy oral fixation and parameter acquisition device (patent number: ZL201921877986.5)’. …”
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    Radiotherapy for head and neck tumours using an oral fixation and parameter acquisition device and TOMO technology: a randomised controlled study
  8. 3248
    “…RESULTS: General trends of statin’ prescriptions were largely driven by a decrease in acquisition costs triggered by patent expiration, preceding NICE guidelines which themselves did not seem to affect prescription trends. …”
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    Price versus clinical guidelines in primary care statin prescribing: a retrospective cohort study and cost simulation model
  9. 3249
    “…Greater initial release of both ions occurred in roots with a patent apex, but by 1 week there was no significant difference between the two. …”
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    Evaluation of the diffusion of calcium hydroxide-based medicaments through the dentinal tubules and apical foramen: A mass spectrometry study
  10. 3250
    “…We synthesized and evaluated a radiolabeled macrocyclic peptide adapted from a patent by Bristol Myers Squibb. Synthesis of [(68)Ga]Ga‐NJMP1 yielded a product with a radiochemical purity>95 % that was evaluated in vitro. …”
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    Evaluation of a Radiolabeled Macrocyclic Peptide as Potential PET Imaging Probe for PD−L1
  11. 3251
    “…CONCLUSIONS: Our study shows that there is significant prevalence of neuropathy in PD patents that affects the quality of life of PD patients. …”
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    Neuropathy in Parkinson's Disease: Risk Determinants and Impact on Quality of Life
  12. 3252
    “…A total of 8126 associated patents led to the identification of 41 therapies that registered clinical trials; 18 of these therapies received FDA approved. …”
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    The Relative Contributions of NIH and Private Sector Funding to the Approval of New Biopharmaceuticals
  13. 3253
    “…This study provides technical and data support for the registration of Chinese patented medicines in the EU, controls quality and ensures safety, and is committed to the internationalization and standardization of Chinese patented medicines.…”
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    Simultaneous Determination of 32 Pyrrolizidine Alkaloids in Two Traditional Chinese Medicine Preparations by UPLC-MS/MS
  14. 3254
    “…Conclusion: Although there is no silver bullet that can balance valuable innovation with affordable access to medicines, (Belgian) policy and decision makers should continue to explore initiatives that exploit the potential of both the on-patent and off-patent pharmaceutical markets.…”
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    How to balance valuable innovation with affordable access to medicines in Belgium?
  15. 3255
    por Wang, Hui
    Publicado 2022
    “…He developed the 4Pi microscope and successfully increased the vertical resolution of traditional optical microscopes by 3–7 times. Once he sold the patent to a company, he invested the little personal money gained from the patent in breaking the Abbe diffraction limit. …”
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    Light People: Professor Stefan Hell
  16. 3256
    “…The inferior vena cava was patent, with no thrombus. Old superficial femoral vein thrombosis could be seen in the right lower extremity. …”
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    Case report: Endoluminal removal of a retrievable conical inferior vena cava filter with a ruptured retraction hook attached to the wall
  17. 3257
    “…This paper addresses the spatial pattern of urban biomedicine innovation networks by separately using four scales, i.e., the national scale, interregional scale, urban agglomeration scale, and provincial scale, on the basis of Chinese biomedicine patent data from the incoPat global patent database (GPD) (2001–2020) and using the method of social network analysis (SNA). …”
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    Research on the evolution of the Chinese urban biomedicine innovation network pattern: An analysis using multispatial scales
  18. 3258
    “…Among cardiac malformations, atrial septal defect, patent ductus arteriosus, patent foramen ovale and mitral valve prolapse were the most common findings, but other unspecified defects, such as mild pulmonary valve stenosis, were also described. …”
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    Helsmoortel–Van der Aa Syndrome—Cardiothoracic and Ectodermal Manifestations in Two Patients as Further Support of a Previous Observation on Phenotypic Overlap with RASopathies
  19. 3259
    “…CONCLUSIONS: A patent foramen ovale is found in approximately 15–20% of healthy individuals. …”
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    Cerebral infarction by paradoxical gas embolism detected after laparoscopic partial hepatectomy with an insufflation management system: a case report
  20. 3260
    “…We observed absence of epiphora and a patent nasolacrimal duct on irrigation in 105 out of 126 treated eyes. …”
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    Transcanalicular diode laser-assisted dacryocystorhinostomy
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