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4841“…The method of preparation, characterization, factors affecting nanosponge development, drug loading and release mechanism, recent developments in this area, and patents filed in the area of nanosponges are all highlighted in this study. …”
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4842por Raina, Neha, Pahwa, Rakesh, Bhattacharya, Jaydeep, Paul, Alok K., Nissapatorn, Veeranoot, de Lourdes Pereira, Maria, Oliveira, Sonia M. R., Dolma, Karma G., Rahmatullah, Mohammed, Wilairatana, Polrat, Gupta, Madhu“…The outcome of various studies on the use of hydrogels in different segments and how they have been appropriately altered in numerous ways to attain the desired targeted delivery of therapeutic agents is summarized. Patents and clinical trials conducted on hydrogel-based products, along with scale-up translation, are also mentioned in detail. …”
Publicado 2022
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4843por Husain, Asif, Chanana, Harshit, Khan, Shah Alam, Dhanalekshmi, U. M., Ali, M., Alghamdi, Anwar A., Ahmad, Aftab“…This manuscript highlights the basic characteristics, chemistry, biosynthesis, stability profiling, chemical synthesis, physicochemical parameters along with various analytical methods developed for extraction, isolation and characterization, diverse biological activities and granted patents to this lead anthocyanin molecule, Dp. This review aims to open pathways for further exploration and research investigation on the true potential of the naturally occurring purple pigment (Dp) in its anthocyanidin and anthocyanin forms beyond nutrition.…”
Publicado 2022
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4844“…This study uses data source patents obtained by 285 focal firms in the Chinese new-energy vehicle industry in the period 2015–2020. …”
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4845por Wang, Jilong, Jin, Zongrui, Xu, Banghao, Chen, Weitao, Zhang, Jianyong, Zhu, Hai, Lu, Tingting, Zhang, Ling, Guo, Ya, Wen, Zhang“…During the post-operative examination and follow-up, the blood flow of the ePTFE graft was patent, and liver function recovered well. Thus, robotic hepatectomy with MHV reconstruction is a safe, minimally invasive, and precise surgery that may provide a novel approach for patients with liver tumors that are invading or adjacent to the main hepatic veins.…”
Publicado 2022
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4846“…Follow-up images after 39 months showed a patent artery with no recurrence of any cystic lesions, highlighting successful ACD treatment via stenting, ultrasound-guided aspiration, and cyst drainage. …”
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4847“…RESULTS: Cardioembolism due to paroxysmal atrial fibrillation, patent foramen ovale, or cardiomyopathy; occult atherosclerosis from unstable plaques and hypercoagulable conditions seem to be the most common underlying causes to be revealed by further investigations. …”
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4848por Jin, Hui-Ying, Li, Hai-Feng, Xu, Jia-Lu, Hui, Wang, Ruan, Wen-Cong, Lv, Cheng-Cheng, Xu, Ren-Ai, Qiang, Shu“…Transient hypoglycemia, abnormal cranial magnetic resonance imaging, multiple nodules in polycystic kidneys and liver, abnormal hearing, patent ductus arteriosus, and an atrial septal defect were also noted. …”
Publicado 2022
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4849por Souza, Tainá Santos, Moreira, Diogo Rodrigo Magalhães, Marcelino, Henrique Rodrigues“…The search was conducted in several databases, including scientific and patent databases. Pharmaceutical nanotechnology and medicinal chemistry are the tools of choice to achieve human applications, and most of these applications have been able to improve the biopharmaceutical properties and pharmacokinetic profile of DQ. …”
Publicado 2022
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4850“…LJF and LF are commonly used in Chinese patent drugs. In the Chinese Pharmacopoeia, LJF and LF once belonged to the same source. …”
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4851por Li, Siming, Li, Xiaoling, Wang, HeMeng, Jia, Xinhang, Mao, Haoyang, Dong, Fangxin, Zhao, Tingting, Gao, Yuan, Zhang, Chen, Bai, Ruisong, Liu, Ruihao, Yan, Lijun, Ji, Yubin, Zhang, Na, Wang, Wenfei“…JinQi Jiangtang tablet (JQJTT) is a Chinese patent medicine that has been shown to be beneficial for patients with diabetes both preclinically and clinically; however, the molecular mechanism underlying the effects of JQJTT remains unclear. …”
Publicado 2022
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4852por Yue, Xuan, Chen, Zhejie, Zhang, Jinming, Huang, Chi, Zhao, Shiyi, Li, Xuebo, Qu, Yan, Zhang, Chen“…Besides, the structure-activity relationship, application prospect and patent application of LPs were analyzed and summarized. …”
Publicado 2022
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4853“…Pfizer and the Medicines Patent Pool (MPP) have reached a voluntary licensing agreement for Paxlovid (nirmatrelvir+ritonavir), a novel antiviral for coronavirus disease 2019 (COVID-19) taken orally in the first 5 days from symptom onset. …”
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4854“…BACKGROUND: The coexistence with patent ductus arteriosus (PDA), mitral valve prolapse (MVP), atrial fibrillation (AF) and hyperthyroidism is extremely rare and complex. …”
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4855por Rai, Vikrant, Radwan, Mohamed M, Nooti, Sunil, Thankam, Finosh G, Singh, Harbinder, Agrawal, Devendra K.“…Thus, targeting TLR-4 to attenuate inflammation and early thrombosis might be a therapeutic approach to keep AVF patent and maintain blood flow through the outflow vein.…”
Publicado 2022
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4856“…DISCUSSION: CECT scan in over half of the AMI patients may show patent mesenteric vessels. However, such patency of mesenteric vessels should not rule out the possibility of AMI in cases of COVID-19 with prominent GI signs and symptoms, especially those admitted in ICU. …”
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4857por Listro, Roberta, Rossino, Giacomo, Piaggi, Federica, Sonekan, Falilat Folasade, Rossi, Daniela, Linciano, Pasquale, Collina, Simona“…A general outlook on the approved drugs, recent patents, and current research in this field is herein provided, and the role of the urea moiety in the drug discovery process is discussed form a medicinal chemistry standpoint. …”
Publicado 2022
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4858por Kumar, Harsh, Aggarwal, Navidha, Marwaha, Minakshi Gupta, Deep, Aakash, Chopra, Hitesh, Matin, Mohammed M., Roy, Arpita, Emran, Talha Bin, Mohanta, Yugal Kishore, Ahmed, Ramzan, Mohanta, Tapan Kumar, Saravanan, Muthupandian, Marwaha, Rakesh Kumar, Al-Harrasi, Ahmed“…In this manuscript, an effort has been made to review the research on TZD derivatives as potential antimicrobial, antioxidant, and antihyperglycemic agents from the period from 2010 to the present date, along with their molecular mechanisms and the information on patents granted to TZD analogues.…”
Publicado 2022
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4859“…Several physical eye models have been reviewed from peer-reviewed papers and patent applications. A typical eye model includes an artificial cornea, an intraocular lens or other lens to simulate the crystalline lens, an aperture as the pupil, and a posterior retinal surface, which may be connected to a light sensor. …”
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4860por Zhang, Xi, Luo, Tao, Mou, Yan-Rong, Jiang, Wei, Wu, Yan, Liu, Heng, Ren, Yi-Ming, Long, Pan, Han, Fei“…Detailed morphological and functional examinations of the retina revealed that the lesions of the three patients had many similar characteristics, such as macular morphological changes, patent pattern visual monitoring amplitude or peak time abnormalities, multi-fucus electroretinograms macular central amplitude density decreased. …”
Publicado 2022
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