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  1. 5141
    “…The review concludes with a brief discussion on the patentability and regulatory issues related to pharmaceutical cocrystals.…”
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    Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems
  2. 5142
    por Pessa, Joel E.
    Publicado 2023
    “…Fluorescent injection confirms that these channels are patent and that flow occurs independent of the venous system. …”
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    Identification of a novel path for cerebrospinal fluid (CSF) drainage of the human brain
  3. 5143
    “…The models predict the likelihood of R&D success, commercialization, and patent applications within 5 years of project completion. …”
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    Prediction of SMEs’ R&D performances by machine learning for project selection
  4. 5144
    “…Recent data suggest that the burden of non-ischemic CS is increasing in the population of patents requiring intensive care admission. There is, however, a paucity of data and guidelines to inform the management of these patients who fall into two broad groups: those with existing heart failure and CS and those with no known history of heart failure who present with “de novo” CS. …”
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    The role of temporary mechanical circulatory support in de novo heart failure syndromes with cardiogenic shock: A contemporary review
  5. 5145
    “…This review analyzes commonly used TCM patent drugs and TCM decoctions that are applicable to different stages of CHF based on clinical trials. …”
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    The traditional Chinese medicines treat chronic heart failure and their main bioactive constituents and mechanisms
  6. 5146
    “…Presently, two top-ranked substances underwent successful patent filing. In addition, the study demonstrates how to work around reported VS pitfalls in detail.…”
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    Targeting the Human Influenza a Virus: The Methods, Limitations, and Pitfalls of Virtual Screening for Drug-like Candidates Including Scaffold Hopping and Compound Profiling
  7. 5147
    “…It shows good compatibility with most inorganic/organic fillers, and enhanced composites may be prepared without the need to introduce coupling agents and interfacial modifiers. The patented high amorphous polyvinyl alcohol (HAVOH), commercialized with the trade name G-Polymer, can be easily dispersed in water and melt processed. …”
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    Synthesis and Electrical Percolation of Highly Amorphous Polyvinyl Alcohol/Reduced Graphene Oxide Nanocomposite
  8. 5148
    “…The search was conducted in the main public databases (PubChem, PubMed, Science Direct, and Google Scholar) and in the Espacenet database (European Patent Office—EPO) and the Brazilian National Property Institute (INPI). …”
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    Seaweeds and Corals from the Brazilian Coast: Review on Biotechnological Potential and Environmental Aspects
  9. 5149
    “…CONCLUSION: Myocardial infarction in patent coronary arteries due to an anterior mediastinal mass is rare. …”
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    Non-ST-segment elevation myocardial infarction with non-obstructive coronary arteries due to a type-A thymoma: A case report
  10. 5150
    por Li, Shiding, Chen, Liangbo, Fu, Yao
    Publicado 2023
    “…Besides, we summarize the nanotechnology-based ophthalmic drugs currently on the market or still in clinical trials and the recent patents of nanocarriers. Finally, inspired by current trends and therapeutic concepts, we provide an insight into the challenges faced by novel ocular drug delivery systems and further put forward directions for future research. …”
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    Nanotechnology-based ocular drug delivery systems: recent advances and future prospects
  11. 5151
    “…S. borneensis and its natural products have important and potentially patentable pharmacological properties. In particular, the seeds have the potential to be used as a source of food preservatives, antiseptics, or termiticides. …”
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    The Garlic Tree of Borneo, Scorodocarpus borneensis (Baill.) Becc. (Olacaceae): Potential Utilization in Pharmaceutical, Nutraceutical, and Functional Cosmetic Industries
  12. 5152
    “…Follow-up lower extremity computed tomographic angiography showed a patent popliteal artery without any claudication in both two cases. …”
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    A case series: patients with complicated popliteal artery entrapment syndrome successfully treated with a hybrid surgical and interventional treatment
  13. 5153
    “…The paper uses spatial panel data on the number of patents in the field of sports in each province from 2017–2022 to explore the spatial and temporal evolution process of the innovation capacity of China’s sports industry and analyze its development trend based on theories related to economic geography, using exploratory spatial data analysis (ESDA) and Spatial-temporal correlation analysis research methods. …”
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    Analysis of the spatial and temporal evolution process and development trend of innovation capability of Chinese sports industry
  14. 5154
    por Xia, Nan
    Publicado 2023
    “…A discussion follows on how China, under foreign pressure, has made efforts to comply with the changing standards mandated by various international, regional, and bilateral arrangements related to intellectual property, with examples of the development of China’s patent law. China’s approach towards the protection of traditional medical knowledge in various international fora related to intellectual property is explored. …”
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    Intellectual property protection for traditional medical knowledge in China’s context: a round peg in a square hole?
  15. 5155
    “…There was an increase in quality-adjusted life years (QALYs) when incorporating glucosamine in conventional care. Moreover, patented crystalline glucosamine sulfate (pCGS) was more cost-effective than the other formulations of glucosamine (OFG). …”
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    Cost-Effectiveness of Glucosamine in Osteoarthritis Treatment: A Systematic Review
  16. 5156
    por Frihart, Charles R.
    Publicado 2023
    “…The specific structures and amounts of the diacids and diamines and their relative ratios have a big effect on the bio-based polyamide mechanical properties, but analysis of the structure–property relationships has seldom been attempted, since the data are mainly in the patent literature. The diacids derived from plant oils are valuable for making polyamides because of their very high bio-based content and highly tunable properties.…”
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    Chemistry of Dimer Acid Production from Fatty Acids and the Structure–Property Relationships of Polyamides Made from These Dimer Acids
  17. 5157
    por van Elk, Michiel, Fried, Eiko I.
    Publicado 2023
    “…This optimism is reflected in an increase in research papers, investments by pharmaceutical companies, patents, media coverage, as well as political and legislative changes. …”
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    History repeating: guidelines to address common problems in psychedelic science
  18. 5158
    “…In this review, we will shed light on the composition, methods of preparation, classification, surface functionalization, release mechanism, advantages and disadvantages, patents, and clinical trials of LPHNPs, with an emphasis on core–shell-structured LPHNPs.…”
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    Lipid–Polymer Hybrid Nanosystems: A Rational Fusion for Advanced Therapeutic Delivery
  19. 5159
    “…The postoperative MRI showed a patent third ventriculostomy, without complication, and a significant decrease in supratentorial ventricular size. …”
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    Symptomatic obstructive hydrocephalus caused by choroid plexus hyperplasia in a pediatric patient: illustrative case
  20. 5160
    Publicado 2021
    “…Parasitologists rapidly introduced newly developed Praziquantel, and Korean chemists quickly reverse engineered the compound to evade patent issues. This allowed for the mass production of Praziquantel at a lower price, which in turn enabled a nationwide Clonorchiasis control program. …”
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    1970-1980년대 한국 구충제 생산 기술 형성과 활용 : 프라지콴텔 국산화와 간흡충 관리 사업
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