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5261por Andrade, Fernanda, Rafael, Diana, Videira, Mafalda, Ferreira, Domingos, Sosnik, Alejandro, Sarmento, Bruno“…Besides the development of new anti-infectious drugs, the development of innovative and more efficient delivery systems for drugs that went off patent appears as a promising strategy pursued by the pharmaceutical industry to improve the therapeutic outcomes and to prolong the utilities of their intellectual property portfolio. …”
Publicado 2013
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5262por Kamezaki, Hidehiro, Tsuyuguchi, Toshio, Shimura, Kenji, Sakamoto, Dai, Senoo, Junichi, Mizumoto, Hideaki, Kubota, Michio, Yoshida, Yu, Azemoto, Ryosaku, Sugiyama, Harutoshi, Kato, Naoya“…The present study aimed to assess the feasibility and risks of early removal of the PTGBD tube under the scenario of subsiding inflammation, patent cystic and common bile ducts, and absence of intraperitoneal leakage. …”
Publicado 2020
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5263por Patinote, Cindy, Karroum, Nour Bou, Moarbess, Georges, Cirnat, Natalina, Kassab, Issam, Bonnet, Pierre-Antoine, Deleuze-Masquéfa, Carine“…We gather in this review more than 360 scientific publications, reviews and patents, relating the extensive work carried out by researchers on the design of TLRs 7/8 modulators, which are classified firstly by their biological activities (agonist or antagonist) and then by their chemical structures, which total syntheses are not discussed here. …”
Publicado 2020
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5264“…This vessel was once again recruited by percutaneous approach and it is still patent and in catch-up growth after 6 months from the second recanalization procedure.…”
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5265por Zhang, Jingyuan, Liu, Xinkui, Zhou, Wei, Cheng, Guoliang, Wu, Jiarui, Guo, Siyu, Jia, Shanshan, Liu, Yingying, Li, Bingbing, Zhang, Xiaomeng, Wang, Miaomiao“…Yinzhihuang granules (YZHG) is a patented Chinese medicine for the treatment of hepatitis B. …”
Publicado 2020
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5266por de Almeida Magalhães, Thalita Sévia Soares, de Oliveira Macedo, Pollyana Cristina, Converti, Attilio, Neves de Lima, Ádley Antonini“…In this review, a search for literature and patent technological prospecting has been performed on the use of EO to treat and prevent diseases as well as to prepare pharmaceutical formulations. …”
Publicado 2020
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5267“…We present a tigecycline administration in a 5-month-old infant with patent arterial duct, heart failure, and respiratory failure due to respiratory syncytial virus bronchiolitis with subsequent respiratory distress syndrome and severe sepsis caused by multi-drug-resistant Pseudomonas aeruginosa. …”
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5268por Nardi-Ricart, Anna, Nofrerias-Roig, Isaac, Suñé-Pou, Marc, Pérez-Lozano, Pilar, Miñarro-Carmona, Montse, García-Montoya, Encarna, Ticó-Grau, Josep R., Insa Boronat, Raul, Suñé-Negre, Josep M.“…These surprising and novel results have given rise to patent number WO/2018/019997.…”
Publicado 2020
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5269por de Klerk, Johan C. A., Engbers, Aline G. J., van Beek, Floor, Flint, Robert B., Reiss, Irwin K. M., Völler, Swantje, Simons, Sinno H. P.“…The optimal management strategy for patent ductus arteriosus in preterm infants remains a topic of debate. …”
Publicado 2020
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5270“…The main reason is the disruptive character of the genome editing technologies due to their potential for novel, ground-breaking solutions in agriculture and aquaculture combined with the economic framework shaped by the patent system. Food is fundamental for a good life, biologically and culturally, which warrants stricter assessment procedures than what is required for other industries, at least in countries like Norway with a strong tradition for national control over agricultural markets and breeding programs.…”
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5271por Griffiths, Megan, Yang, Jun, Everett, Allen D., Jennings, Jacky M., Freire, Grace, Williams, Monica, Nies, Melanie, McGrath-Morrow, Sharon A., Collaco, Joseph M.“…ST2 concentrations predicted right to left patent ductus arteriosus flow (p=0.009). NT-proBNP was not associated with PH features. …”
Publicado 2020
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5272“…In this review, we presented a compilation of recent publications, clinical trials and patents, addressing the potential of lncRNAs that could be considered as biomarkers or therapeutic targets, with the hopes of providing promised implications for future cancer therapy.…”
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5273por Batista-Filho, João, Falcão, Maria Alice Pimentel, Maleski, Adolfo Luis Almeida, Soares, Amanda Beatriz Silva, Balan-Lima, Leticia, Disner, Geonildo Rodrigo, Lima, Carla, Lopes-Ferreira, Monica“…The patented anti-inflammatory peptide TnP had its effectiveness recently confirmed in vivo in a murine model of multiple sclerosis and asthma. …”
Publicado 2020
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5274“…Yufengingxin (YFNX) is a commonly used Chinese patent medicine in CHD angina treatment. The purpose of this protocol is to evaluate the effectiveness and safety of YFNX for the treatment of CHD angina. …”
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5275“…The pandemic has created the need for a rapid detection of technological convergence phenomena, but at the same time it has made clear that this task is impossible on the basis of traditional patent and publication indicators. This paper presents a novel methodology to perform a rapid detection of the fast technological convergence phenomenon that is occurring under the pressure of the Covid-19 pandemic. …”
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5276por Kim, Sunghwan, Chen, Jie, Cheng, Tiejun, Gindulyte, Asta, He, Jia, He, Siqian, Li, Qingliang, Shoemaker, Benjamin A, Thiessen, Paul A, Yu, Bo, Zaslavsky, Leonid, Zhang, Jian, Bolton, Evan E“…Data from more than 100 new data sources were added to PubChem, including chemical-literature links from Thieme Chemistry, chemical and physical property links from SpringerMaterials, and patent links from the World Intellectual Properties Organization (WIPO). …”
Publicado 2020
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5277“…Additionally, a type A IAA, an intact ventricular septum, and a large patent ductus arteriosus were revealed. Computed tomography angiography with 3-dimensional reconstruction confirmed above findings. …”
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5278por Mohlkert, Lilly-Ann, Hallberg, Jenny, Broberg, Olof, Sjöberg, Gunnar, Rydberg, Annika, Liuba, Petru, Fellman, Vineta, Domellöf, Magnus, Norman, Mikael, Pegelow Halvorsen, Cecilia“…We also examined relations between birth size, gestational age, neonatal diagnoses of bronchopulmonary dysplasia (BPD) and patent ductus arteriosus (PDA) with cardiac outcomes. …”
Publicado 2020
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5279por Vieira, Amanda A., Vianna, Giovanni R., Carrijo, Jessica, Aragão, Francisco J. L., Vieira, Pabline M.“…Genes of this microorganism have been studied, and their applications are patented for use in biofungicides and plant breeding strategies. …”
Publicado 2021
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5280“…In the view of technology, the store-and-forward (asynchronous/hybrid) and a real-time (synchronous) methods were introduced with one applied and nine registered patents recorded from 2004 to 2020 for the invention of teleaudiology in the United States. …”
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