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  1. 5361
    “…Present tendency is to modulate IQC considering the workload and the impact of analytical failure in the patent harm. CONCLUSIONS: This paper remarks the strong points of IQC models, indicates the weak points that should be eliminated from practice and gives a future projection on how to promote patient safety through laboratory examinations.…”
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    Internal quality control – past, present and future trends
  2. 5362
    “…The interest in this spinning technology is evident from the growing number of patents issued and articles published over the last few years. …”
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    Advances in Biomedical Applications of Solution Blow Spinning
  3. 5363
    “…The recent expiration of patents for the antibiotic tulathromycin has led to a significant increase in the number of generic tulathromycin products (GTPs) available. …”
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    Evaluation of Biological Equivalence for Generic Tulathromycin Injections in Cattle
  4. 5364
    “…Pediatric drug studies are stimulated in the USA by the pediatric exclusivity provision under the Food and Drug Administration Modernization Act (FDAMA) that grants patent extensions when pediatric labeling is provided. …”
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    Stimulation programs for pediatric drug research – do children really benefit?
  5. 5365
    “…Serial sections of the ureter revealed several small and discontinuous lacunae lined by cuboidal and transitional epithelium, which did not constitute a patent lumen through the bladder. This case is a rare case of renal dysplasia with defect in recanalization of the ureteral bud during the early developmental stage.…”
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    Histochemical Analysis of Renal Dysplasia with Ureteral Atresia
  6. 5366
    por Bang, Oh Young
    Publicado 2009
    “…Second, multimodal MRI for identifying stroke mechanisms and the specific causes of stroke (i.e., patent foramen ovale, infective endocarditis, and nonbacterial thrombotic endocarditis) are presented, followed by MRI strategies for prevention of recurrent stroke: plaque images and flow dynamics for carotid intervention. …”
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    Multimodal MRI for Ischemic Stroke: From Acute Therapy to Preventive Strategies
  7. 5367
    “…The objective of this study was to investigate the efficacy and tolerability of sumatriptan 50 mg vs. placebo in migraine patents with infrequent migraine attacks when medication is taken during the mild phase of an attack. …”
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    Treatment with sumatriptan 50 mg in the mild phase of migraine attacks in patients with infrequent attacks: a randomised, double-blind, placebo-controlled study
  8. 5368
    “…Follow-up imaging demonstrated a patent drainage tract without evidence of recurrence. …”
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    Upper Nasopharyngeal Corridor for Transnasal Endoscopic Drainage of Petroclival Cholesterol Granulomas: Alternative Access in Conchal Sphenoid Patients
  9. 5369
    por Sabzi, Freidoun, Faraji, Reza
    Publicado 2016
    “…Transthoracic echocardiography showed a huge left atrial myxoma, and computed tomography scan illustrated paradoxical pulmonary embolism in the left upper lung lobe via a large patent foramen ovale. The tumor required urgent cardiac surgery. …”
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    Preoperative Emboli in a Pregnant Woman with Myxoma
  10. 5370
    por Pepeta, Lungile, Dippenaar, Adele
    Publicado 2013
    “…METHODS: Records of patients admitted for percutaneous closure of patent ductus arteriosus (PDA) were reviewed. RESULTS: From May 2009 to July 2012, 36 patients were assigned to closure using the ADO II. …”
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    Ductal closure using the Amplatzer duct occluder type two: experience in Port Elizabeth hospital complex, South Africa
  11. 5371
    por Lexchin, Joel
    Publicado 2016
    “…Therapeutic innovation evaluations came from the Patented Medicine Prices Review Board (PMPRB) and Prescrire International. …”
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    How Safe and Innovative Are First-in-Class Drugs Approved by Health Canada: A Cohort Study
  12. 5372
    “…Mutations inTFAP2B has been reported in patients with isolated patent ductus arteriosus (PDA) and Char syndrome. …”
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    TFAP2B mutation and dental anomalies
  13. 5373
    “…A spring nature, clip component was selected out of a newly designed medical device (patented) to perform this reliability study. This clip component was sterilized for a predetermined number of cycles (2, 4, 6, 8, 10, 20…100) at 121 °C for 30 min. …”
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    Effects of Sterilization Cycles on PEEK for Medical Device Application
  14. 5374
    “…A biosimilar is a biologic product that is highly similar to a licensed biologic (“originator”) such that there are no clinically meaningful differences in safety, purity, or potency between the biosimilar and the originator. As patent protection and data exclusivity for the biologic rituximab expire, several potential biosimilars to rituximab are in development, which could soon lead to the availability of numerous rituximab biosimilars. …”
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    Biosimilars Have Arrived: Rituximab
  15. 5375
    por D.Levit, Rebecca
    Publicado 2018
    “…After decellularization and transplantation as an arteriovenous fistula, this group showed that grafts remained patent for several weeks. The lack of cellular material in this graft at the time of transplantation reduced the risk of immune rejection. …”
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    Engineering Vessels as Good as New?
  16. 5376
    “…The new compound displays low levels of cytotoxicity against THP-1 and A549 cells with a selective index (SI) > 8 (patent application PCT/IB2017/054870, August 2017). …”
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    Novel Guanidine Compound against Multidrug-Resistant Cystic Fibrosis-Associated Bacterial Species
  17. 5377
    “…A patented organotin di-n-butyl-di-(4-chlorobenzohydroxamato)tin (DBDCT) with high a antitumor activity was designed, however, its antitumor and toxic mechanisms have not yet been clearly illustrated. …”
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    Proteomics Analysis Reveals an Important Role for the PPAR Signaling Pathway in DBDCT-Induced Hepatotoxicity Mechanisms
  18. 5378
    “…The drug in question is commonly sought after by pharmaceutical industries that produce generic drugs, due to the fact that the drug has a high value price, it is consumed globally, and its patent expired in late 2010. Many questions concerning this drug’s pharmaceutical scope demonstrate its importance regarding stability studies and the identification of degradation products of drugs and pharmaceutical formulations. …”
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    Degradation Kinetics of Atorvastatin under Stress Conditions and Chemical Analysis by HPLC
  19. 5379
    “…Viewing a metabolomic biomarker as a natural phenomenon would inhibit patent protection and potentially stifle commercial interest. …”
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    A Framework for Development of Useful Metabolomic Biomarkers and Their Effective Knowledge Translation
  20. 5380
    por Dang, Huy Q., Le, Huong T.
    Publicado 2019
    “…CASE PRESENTATION: We described an 8-year-old girl, weighing 17 kg, who was diagnosed with peri-membranous VSD and patent ductus arteriosus (PDA). The patient had undergone trans-catheter PDA closure first, and 3 weeks later, TES was performed for VSD repair through 4 small trocars (one 12 mm trocar and three 5 mm trocars) without robotic assistance. …”
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    Totally endoscopic ventricular septal defect repair using bilateral femoral arterial cannulation in an 8-year-old girl
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