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5521“…Small-molecule drugs, once the patent term has expired, provide a uniquely sustainable form of healthcare.…”
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5522por Chen, Chao-Lin, Guo, How-Ran, Wang, Ying-Jan, Chang, Hong-Tai, Pan, Chui-Yi, Tuan-Mu, Ho-Yi, Lin, Hsiu-Chuan, Chen, Chao-Yi, Hu, Jin-Jia“…In comparison with those without cyclic dynamic stimuli, tubular tissues with this treatment during in vivo culture had stronger mechanical properties, better smooth muscle differentiation, and more collagen and elastin expression by the end of incubation period in the peritoneal cavity. The grafts remained patent after 4 months of implantation and showed the presence of endothelial and smooth muscle cells. …”
Publicado 2019
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5523“…Many patents for the first biologicals derived from recombinant technology and, more recently, monoclonal antibodies (mAbs) are expiring. …”
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5524“…The patient was a full-term male with trisomy 21, agenesis of corpus callosum, ventricular septal defect, patent ductus arteriosus, right-sided aortic arch, and congenital absence of sternum with no sternal bars. …”
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5525por Niinomi, Iku, Hosohata, Keiko, Mori, Yasuhiro, Yamaguchi, Yuki, Wakabayashi, Tomohito, Uchida, Mayako, Iwanaga, Kazunori“…The high cost of IFX and its patent expiry have led to pharmaceutical companies developing a biosimilar; however, its safety profile remains unknown in the real world. …”
Publicado 2019
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5526“…MATERIAL AND METHODS: The search for inventions was carried out in the databases, such as Google Patent, Google Scholar, Scopus, and PubMed. The key words used in this search were as follows: toothbrushes, toothpicks, toothpastes, plaque, cleaning products for teeth and dentures, teeth whiteners and dentures, bleach bruises and blood stains, pus, sulfur plugs, and pus solvents. …”
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5527“…Obliteration of the VAVF with a balloon while the parent vertebral artery is still patent is very possible.…”
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5528por Zuo, Tiantian, Qian, Yuexin, Zhang, Chunxia, Wei, Yuxi, Wang, Xiaoyan, Wang, Hongda, Hu, Ying, Li, Weiwei, Wu, Xiaohui, Yang, Wenzhi“…Compound Xueshuantong Capsule (CXC) is a four-component Chinese patent medicine prescribed to treat ophthalmic disease and angina. …”
Publicado 2019
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5529por Romanis, Elizabeth Chloe“…Second, I argue that there is nothing unique about pregnancy that displaces the ethical norm of respecting patents’ sufficiently autonomous choices. Thus, the starting presumption is that all informed choices regarding MRCS should be respected. …”
Publicado 2019
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5530“…The second part of the paper discusses the incorrect use of the term “lipoma” for retroperitoneal fat, which penetrated into the lumen of the patent processus vaginalis – the authors using this term acknowledge its incorrectness. …”
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5531“…We found that, in addition to the vector's saliva, the PSG from L. major and L. tropica potently exacerbated cutaneous infection in BALB/c mice, improved the probability of developing a patent cutaneous lesion, parasite growth and the evolution of the lesion. …”
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5532por Chen, Peng, Wang, Yu-zhu, Liu, Qi-zhi, Li, Wei-hua, Li, He-qin, Li, Xing-yue, Zhang, Yun-tao“…BACKGROUND: In strawberry cultivation, continuous cropping (CC) obstacles seriously threaten production. A patented soil amendment (SA) can effectively relieve the CC obstacles to strawberry cultivation, but knowledge of the recovery mechanisms underlying this phenomenon is limited. …”
Publicado 2020
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5533“…BACKGROUND: Shenmai injection (SMI) is a Traditional Chinese Medicine patent prescription consisting of extractions from ophiopogonis radix and ginseng radix rubra. …”
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5534“…We aimed to introduce patent processus vaginalis (PPV) sac tightening (PVST) technique and compare it to the conventional technique. …”
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5535por Camfferman, Fleur A., de Goederen, Robbin, Govaert, Paul, Dudink, Jeroen, van Bel, Frank, Pellicer, Adelina, Cools, Filip“…Altered perfusion, for example, seen in the context of a hemodynamically significant patent ductus arteriosus (PDA), has been linked to injury of the immature brain. …”
Publicado 2020
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5536por Rosol, Zachary P, Kopecky, Kathleen F, Minehart, Bailey R, Tecson, Kristen M, Vasudevan, Anupama, McCullough, Peter A, Grayburn, Paul A, Schussler, Jeffrey M“…We defined a change in management as the initiation of anticoagulation therapy, antibiotic therapy or patent foramen ovale closure as a direct result of TOE findings. …”
Publicado 2020
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5537por Tan, Daopeng, Yang, Zhou, Zhang, Qianru, Ling, Hua, Du, Yimei, Lu, Yanliu, Xie, Tianpei, Zhou, Xumei, Qin, Lin, He, Yuqi“…The results also showed that 3,3′,5,7-tetrahydroxy-4′-methoxyflavanone was the most abundant constituent, which could be used as a potential chemical marker for quality control of B. balsamifera and Chinese patent medications containing B. balsamifera herb.…”
Publicado 2020
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5538por Pennance, Tom, Ame, Shaali M., Amour, Armour Khamis, Suleiman, Khamis Rashid, Allan, Fiona, Rollinson, David, Webster, Bonnie L.“…Of 1317 B. globosus/B. nasutus collected, seven B. globosus, identified through sequencing a DNA region of the mitochondrial cytochrome oxidase subunit 1 (cox1), were observed with patent infections assumed to be S. haematobium. However, when the collected cercariae were identified through sequencing a region of the cox1 and the nuclear internal transcribed spacer (ITS1 + 2), schistosomes from five of these B. globosus collected from a single locality were in fact S. bovis. …”
Publicado 2018
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5539por Yin, Qinyan, Strong, Michael J., Zhuang, Yan, Flemington, Erik K., Kaminski, Naftali, de Andrade, Joao A., Lasky, Joseph A.“…Our results do not address the role of viral infection in acute exacerbations of IPF, however, this analysis patently did not support an association between herpes virus detection and IPF.…”
Publicado 2020
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5540por Liu, Jialin, Dong, Xiaoke, Li, Zhonghao, Wang, Gesheng, Zhou, Yujia, Liu, Chongchong, Wang, Kaiyue, Li, Lili, Liu, Jinmin“…Xiaoyukang Jiaonang (XYK) is a Chinese patent medicine approved by the National Medical Product Administration which is used to treat intracranial hematoma in China. …”
Publicado 2020
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