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5961“…We hope this section for Pharmaceutical Patent Protection may help overseas and multinational pharmaceutical companies gain basic knowledge of IPR, design an optimized IPR protection strategy to best fit their products, and achieve a successful product protection for their intellectual property in China.…”
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5962por Rosa, L.A.G., Gomes, M.A., Mundim, A.V., Mundim, M.J.S., Pozzer, E.L., Faria, E.S.M., Viana, J.C., Cury, M.C.“…After inoculation feces were collected daily to determine the pre-patent period, by flotation in 33% zinc sulfate solution. …”
Publicado 2007
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5963por Hebben, Matthias, Duquesne, Véronique, Cronier, Joëlle, Rossi, Bernard, Aubert, André“…However, two studies have shown that poxvirus vectors (vaccinia WR and canarypox) expressing only the FIPV membrane (M) protein can elicit a partially protective immunity which is supposed to be cell-mediated (Virology 181 (1991) 327; International patent WO 97/20054 (1997)). In our study, we report the construction of another poxvirus, the modified vaccinia virus Ankara (MVA), as an expression vector for the FIPV M protein. …”
Publicado 2004
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5964“…Repositioning of old, clinically approved, off patent non-cancer drugs with known targets, into newer indication is like using old weapons for new battle. …”
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5965por Castro-Hermida, José Antonio, García-Presedo, Ignacio, González-Warleta, Marta, Mezo, Mercedes, Fenoy, Soledad, Rueda, Cristina, del Águila, Carmen“…Bobel-24 was effective as a prophylactic/therapeutic treatment at the lowest dose (50 mg/kg of body weight); in the group treated with this dose of drug there was a longer prepatent period, a shorter patent period and a lower intensity of oocyst excretion than in the untreated control group, and the differences were all statistically significant (P < 0.05). …”
Publicado 2008
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5966“…If the gonadal vein is patent, left renal vein occlusion could be treated conservatively.…”
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5967por Meagher, Claire, Franco, Enrico, Turk, Ruth, Wilson, Samuel, Steadman, Nathan, McNicholas, Lauren, Vaidyanathan, Ravi, Burridge, Jane, Stokes, Maria“…The gold standard for measuring muscle activity is electromyography; however, mechanomyography offers an appropriate alterative for our home-based rehabilitation device. We have patent filed a new laboratory-tested device that combines an inertial measurement unit with mechanomyography. …”
Publicado 2020
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5968“…Furthermore, there also are six challenges in the management of manufacturing biomedical products using 3D printing technology, and these include staff re-education, product pricing, limited guidelines, cyber-security issues, marketing, and patents and copyright. This study discusses the reality faced by 3D printing players when producing biomedical products in Malaysia, and presents a primary reference for practitioners in other developing countries.…”
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5969“…INTRODUCTION: Laparoscopic herniotomy (LH) for hydrocele is an accepted procedure and provides advantages of contralateral diagnosis and repair with the same incisions. The suturing of patent processus vaginalis is associated with various complications. …”
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5970“…CONCLUSION: The iuMR imaging features of the CSPV and its close anatomical relations closely correspond to post-mortem data. The CSPV was patent in all cases but we have shown that closure commences in the midpart of the third trimester and advances in a posterior to anterior direction. …”
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5971“…Pharmaceutical co-crystals are novel class of pharmaceutical substances, which possess an apparent probability of advancement of polished physical properties offering stable and patentable solid forms. These multi-component crystalline forms influence pertinent physicochemical parameters like solubility, dissolution rate, chemical stability, physical stability, etc. which in turn result in the materials with superior properties to those of the free drug. …”
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5972“…Rega has developed and patented its own PIU. This device allows spontaneously breathing or mechanically ventilated patients to be transported in pressurized jet cabins, small helicopters and ambulance vehicles, without the need to change between transport units. …”
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5973por Gonçalves, Carla, Silva-Santos, Tânia, Abreu, Sandra, Padrão, Patrícia, Graça, Pedro, Oliveira, Luis, Esteves, Sílvia, Norton, Pedro, Moreira, Pedro, Pinho, Olívia“…TRIAL REGISTRATION NUMBER: NCT03974477 EQUIPMENT PROVISIONAL PATENT NUMBER: Registered at INPI: 20191000033265.…”
Publicado 2020
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5974por Bodin, Justine, Adrien, Amandine, Bodet, Pierre-Edouard, Dufour, Delphine, Baudouin, Stanislas, Maugard, Thierry, Bridiau, Nicolas“…PROT-1 was extracted using a patented acid- and solvent-free process (FR2998894 (B1)). …”
Publicado 2020
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5975“…Success of the procedure was documented as absence of epiphora and patent nasolacrimal duct on syringing. RESULTS: Seventy three patients (males 27; females 46) were included in this study. …”
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5976“…Echocardiography and computed tomography angiography confirmed TGA with anterior-posterior-oriented great arteries, wide patent ductus arteriosus, type B IAA, ventricular septal defect (VSD) and pulmonary arterial hypertension. …”
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5977“…RESULTS: The patient presented with skin tightness, wrist and ankle stiffness, short stature and limbs, several deformed joints in the extremities, cone‐shaped epiphyses, and distinct facial features. He also had a patent foramen ovale and frequent respiratory infections. …”
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5978“…METHODS: 141 representative Chinese formulas and Chinese Patent Medicines from the National Protocol and the most of Provincial Protocols for controlling COVID-19 in China have been collected to statistical analyze the composition and characteristics of CMM. …”
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5979por Zonta, Giulia, Malagù, Cesare, Gherardi, Sandro, Giberti, Alessio, Pezzoli, Alessandro, De Togni, Aldo, Palmonari, Caterina“…This work illustrates the results of a three-year clinical validation protocol (started in 2016) of a patented device composed of a core of nanostructured gas sensors. …”
Publicado 2020
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5980por Serini, Simona, Guarino, Roberta, Ottes Vasconcelos, Renata, Celleno, Leonardo, Calviello, Gabriella“…On this basis, we investigated in vitro the antioxidant/antineoplastic efficacy and anti-aging activity of a dietary supplement containing sulforaphane (SFN), a sulfur-isothiocyanate present in broccoli, combined with the patented extract Fernblock(®) XP (FB), obtained from the tropical fern Polypodium leucotomos. …”
Publicado 2020
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