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  1. 1421
    “…IMPORTANCE: Some sole-source, off-patent drugs in the United States have undergone substantial price hikes in recent years. …”
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    Characteristics and Price Increases Among Sole-Source, Off-Patent Drugs in the United States, 2008 to 2018
  2. 1422
    “…INTRODUCTION: Patent ductus venosus (PDV) is a rare and critical disease, and the majority of patients present with pulmonary arterial hypertension (PAH) or hepatopulmonary syndrome due to congenital portosystemic shunt. …”
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    Ligation of patent ductus venosus in a child with pulmonary arterial hypertension and hypersplenism: A case report
  3. 1423
    “…Herein, we aim to describe a patient with no significant comorbidities who experienced a paradoxical thromboembolic episode of central retinal artery associated with patent foramen ovale.…”
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    Central Retinal Artery Occlusion Secondary to Patent Foramen Ovale: The Unexpected Journey of a Paradoxical Embolus
  4. 1424
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    2-Methyl-pentanoyl-carnitine (2-MPC): a urine biomarker for patent Ascaris lumbricoides infection
  5. 1425
    “…BACKGROUND: Transcatheter device closure is a safe procedure recommended in children with patent ductus arteriosus (PDA). While the standard procedure uses arterial and venous femoral access, it poses risk of vascular complications especially in young infants. …”
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    Comparison of isolated venous approach with the standard approach in children undergoing patent ductus arteriosus device closure
  6. 1426
    “…BACKGROUND: Percutaneous occlusion under fluoroscopy guidance has become the preferred method for the treatment of patent ductus arteriosus (PDA). To avoid radiation exposure and contrast agent use, PDA occlusion under transthoracic echocardiography (TTE) guidance was conducted. …”
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    Transcatheter Closure of Patent Ductus Arteriosus under Echocardiography Guidance: A Randomized Controlled Noninferiority Trial
  7. 1427
    por Zhao, Enfa, Xie, Hang, Zhang, Yushun
    Publicado 2020
    “…Objective: This study aimed to develop and validate a nomogram to predict cessation of patent foramen ovale (PFO) patients with migraine headache after percutaneous closure. …”
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    A Nomogram for the Prediction of Cessation of Migraine Among Patients With Patent Foramen Ovale After Percutaneous Closure
  8. 1428
    por Shi, Xiaoqing, Hua, Yimin, Li, Yifei
    Publicado 2020
    “…OBJECTIVE: Surgical closure of patent ductus arteriosus (PDA) has been considered the only way to rescue preterm neonates following nonsteroidal anti-inflammatory drugs closure failure. …”
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    Transcatheter closure of patent ductus arteriosus in preterm ventilation-dependent neonates: A case series report
  9. 1429
    “…Patent ductus arteriosus (PDA) is a common congenital cardiovascular malformation with both inherited and acquired causes. …”
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    Next Generation Sequencing Identify Rare Copy Number Variants in Non-syndromic Patent Ductus Arteriosus
  10. 1430
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    Aortic thrombosis and renal infarction in a young female with patent foramen ovale and COVID‐19 antibody
  11. 1431
    “…OBJECTIVES: Characterize the safety and effectiveness of the Amplatzer Piccolo Occluder for patent ductus arteriosus (PDA) closure. BACKGROUND: The presence of a hemodynamically significant PDA has been associated with an increased risk of morbidity and mortality in children born premature. …”
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    Amplatzer Piccolo Occluder clinical trial for percutaneous closure of the patent ductus arteriosus in patients ≥700 grams
  12. 1432
    “…We aimed to validate our protocol for the timing of CDH repair using the quantified patent ductus arteriosus (PDA) flow pattern. METHODS: This retrospective comparative study analyzed patients with a prenatal diagnosis of isolated CDH between 2007 and 2020. …”
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    Optimization of surgical timing of congenital diaphragmatic hernia using the quantified flow patterns of patent ductus arteriosus
  13. 1433
    “…Nowadays, a large number of randomized controlled clinical studies have shown that Chinese patent medicine has the advantages of good curative effect and high safety in the treatment of migraine. …”
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    Different Chinese patent medicine therapies for migraine: A protocol for systematic review and network meta-analysis
  14. 1434
    por Kartik, Krishna, Mehta, Chetan.M.
    Publicado 2021
    “…Here we report an unusual case of young female with multiple pulmonary artery aneurysms in bilateral lungs with fusiform dilation of main pulmonary trunk and a small patent ductus arteriosus.…”
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    Multiple pulmonary artery aneurysms in a young female with patent ductus arteriosus on CT pulomnary angiography
  15. 1435
    “…We present an extremely rare combination of biventricular outflow obstruction associated with atrioventricular septal defects and patent ductus arteriosus (PDA). Almost all the other published cases, including ours, were associated with other congenital cardiac lesions other than biventricular outflow obstruction. …”
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    Biventricular Outflow Obstruction Associated With Atrioventricular Septal Defects and Patent Ductus Arteriosus: An Extremely Rare Combination
  16. 1436
    “…INTRODUCTION: Observational studies have shown that migraine has been associated with patent foramen ovale (PFO). Whilst studies investigating PFO closure for the treatment of migraine have been neutral, there is some evidence that symptoms of migraine may improve if the PFO was closed after ischemic stroke. …”
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    Impact of percutaneous patent foramen ovale closure on migraine headaches in patients with history of ischemic neurological events
  17. 1437
    “…This paper explores some recent industrial granted patents related to biocatalysis and bulk chemicals. …”
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    Production of Bulk Chemicals with Biocatalysis: Drivers and Challenges Reflected in Recent Industrial Granted Patents (2015–2020)
  18. 1438
    “…Transthoracic echocardiography and transoesophageal echocardiography demonstrated no evidence of intracardiac thrombus but showed a patent foramen ovale (PFO) with large shunt. After thorough work-up and brain–heart team discussion, we concluded that the patient developed rTTC due to cryptogenic stroke related with her PFO. …”
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    Reverse takotsubo cardiomyopathy caused by patent foramen ovale-related cryptogenic stroke: a case report
  19. 1439
    “…Patients with a large patent ductus arteriosus (PDA) can have several presentations. …”
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    Hybrid retrieval of embolized device in abdominal aorta after transcatheter closure of large patent ductus arteriosus
  20. 1440
    “…This study assessed the state of the art of research activities on AMS through a systematic review of scientific and industrial research. The papers and patents of the last 20 years (2000–2019) were analysed to assess the research tendencies. …”
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    Challenges and Tendencies of Automatic Milking Systems (AMS): A 20-Years Systematic Review of Literature and Patents
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