Mostrando 21 - 40 Resultados de 2,593 Para Buscar '"piccolo"', tiempo de consulta: 2.33s Limitar resultados
  1. 21
    “…A genome-wide association study implicated the polymorphism rs2522833 in the piccolo (PCLO) gene—involved in monoaminergic neurotransmission—as a risk factor for MDD. …”
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    “…Piccolo and Bassoon are the two largest cytomatrix of the active zone (CAZ) proteins involved in scaffolding and regulating neurotransmitter release at presynaptic active zones (AZs), but have long been discussed as being functionally redundant. …”
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    “…Operating clinical analyzers within recommended parameters can be challenging during outbreak response. Using the Piccolo Xpress point-of-care blood chemistry analyzer on guinea pig blood, we found that values of many analytes are still readily comparable when samples and reagent discs are handled at various conditions outside of manufacturer recommendations.…”
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  5. 25
    “…Piccolo is a presynaptic protein with high conservation among different species, and the expression of Piccolo is extensive in vertebrates. …”
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    “…In this study, we use interference RNAs to eliminate Piccolo expression from cultured hippocampal neurons to assess its involvement in synapse formation and function. …”
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  8. 28
    “…Construct validation evidence was compiled by examining the relationship between PICCOLO scores and child age. As expected, teaching domain and total PICCOLO scores were positively correlated with child age. …”
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    “…Moreover, a striking re-distribution of a complex of proteins including Bassoon, Piccolo and Munc 13–1 from the cytoplasm and synapses into intranuclear huntingtin aggregates with loss of active zone proteins and dendritic spines. …”
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    “…We attempted to plug the PDA using an Amplatzer Piccolo Occluder, but the device failed to anchor. …”
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    “…Although PICCOLO has been validated in the United States for children as young as 4 months of age, the current focus is on parents with children aged between 10 and 47 months. …”
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    “…Trio was found to interact with the C-terminal PBH 9/10 domains of Piccolo and Bassoon via its own N-terminal Spectrin repeats, a domain that is also critical for its localization to the CAZ. …”
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  17. 37
    “…The mean age of the children was 29.0 ± 11.9 months. The median PICCOLO score was 43 (interquartile range (IQR)=36-47) in the age-appropriate developmental group, 44 (IQR=35-51) in the questionable group, and 36 (IQR=32-45) in the delayed group. …”
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    Libro
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    “…METHODS: The Pediatric Investigation and Close Collaborative Consortium for Ongoing Life Outcomes for MONitoring Dialysis Outcomes (PICCOLO MONDO) study provided de-identified electronic information of 3244 patients, ages 0–30 years from 2000 to 2012 in four regions: Asia, Europe, North America and South America. …”
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