Mostrando 541 - 560 Resultados de 1,481 Para Buscar '"pneumococcal disease"', tiempo de consulta: 2.00s Limitar resultados
  1. 541
    “…Pneumococcal disease is a major cause of morbidity/mortality worldwide, and vaccination is an important measure in its prevention. …”
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    Pneumococcal Serotype Evolution and Burden in European Adults in the Last Decade: A Systematic Review
  2. 542
    “…Our findings suggest the multifactorial pathogenicity nature of this hypervirulent serotype and provide important evidence for the design of novel protein-based vaccines to prevent and control pneumococcal disease. IMPORTANCE It is important to understand the genetic and pathogenic characteristics of S. pneumoniae serotype 19A, which may provide important information for the prevention and treatment of pneumococcal disease. …”
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    Pan-Genome-Wide Association Study of Serotype 19A Pneumococci Identifies Disease-Associated Genes
  3. 543
    “…Our new workflow is accurate, cost-effective, and can easily be implemented in microbiology laboratories that already perform direct MALDI-TOF identification from positive blood cultures to improve the management of patients with invasive pneumococcal disease. IMPORTANCE: Invasive pneumococcal disease remains a major public health problem worldwide. …”
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    Evaluation of Immulex S. pneumoniae Omni test for the direct detection of S. pneumoniae from positive blood cultures
  4. 544
    “…Neonatal immunisation schedules should therefore be considered in high-risk areas where this may result in improved vaccine coverage and the earliest possible protection against pneumococcal disease and death.…”
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    Pneumococcal conjugate vaccination at birth in a high-risk setting: No evidence for neonatal T-cell tolerance
  5. 545
    “…Previous modelling assumed that the likely impact of PCV7 on invasive pneumococcal disease (IPD) would be similar to the US experience with PCV7. …”
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    7-Valent Pneumococcal Conjugate Vaccination in England and Wales: Is It Still Beneficial Despite High Levels of Serotype Replacement?
  6. 546
    “…METHODS: Cases of pneumococcal disease avoided were calculated through a dynamic model based on the work of Anderson and May (1999). …”
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    Budget impact analysis of a pneumococcal vaccination programme in the 65-year-old Spanish cohort using a dynamic model
  7. 547
    “…It has been suggested that genetic variants in mannose binding lectin (MBL2) influence susceptibility and outcome of invasive pneumococcal disease. We assessed the influence of genetic variation in MBL2 on susceptibility, outcome and causative serotype of pneumococcal meningitis in a prospective nationwide cohort study including 299 white patients and 216 controls. …”
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    Genetic Variation and Cerebrospinal Fluid Levels of Mannose Binding Lectin in Pneumococcal Meningitis Patients
  8. 548
    “…Hospitalization of the elderly for invasive pneumococcal disease is frequently accompanied by the occurrence of an adverse cardiac event; these are primarily new or worsened heart failure and cardiac arrhythmia. …”
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    Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac Function
  9. 549
    “…A prerequisite for pneumococcal disease and transmission is colonization of the nasopharynx. …”
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    Single-Plex Quantitative Assays for the Detection and Quantification of Most Pneumococcal Serotypes
  10. 550
    “…Pneumococcal conjugate vaccines (PCVs) have substantially reduced morbidity and mortality of pneumococcal disease. The impact of the 7-valent PCV on all-serotype invasive pneumococcal disease (IPD) among children was reported to vary between high-income countries. …”
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    The Serotype Distribution among Healthy Carriers before Vaccination Is Essential for Predicting the Impact of Pneumococcal Conjugate Vaccine on Invasive Disease
  11. 551
    “…While significant protection from pneumococcal disease has been achieved by the use of polysaccharide and polysaccharide-protein conjugate vaccines, capsule-independent protection has been limited by serotype replacement along with disease caused by nonencapsulated Streptococcus pneumoniae (NESp). …”
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    Nonencapsulated Streptococcus pneumoniae: Emergence and Pathogenesis
  12. 552
    “…Since the epidemiology of pneumococcal disease is constantly changing, with an increase in nonvaccine pneumococcal serotypes, vaccination policies on the effectiveness and usefulness of vaccines require regular revision. …”
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    The Saudi Thoracic Society pneumococcal vaccination guidelines-2016
  13. 553
    “…New antigens associated with pneumococcal disease virulence were used to test the delivery and adjuvant capabilities of a hybrid biological-biomaterial vector consisting of a bacterial core electrostatically coated with a cationic polymer. …”
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    In situ pneumococcal vaccine production and delivery through a hybrid biological-biomaterial vector
  14. 554
    “…PCVs decrease vaccine-type pneumococcal carriage, a prerequisite for invasive pneumococcal disease, and thereby affects pneumococcal disease and transmission. …”
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    Pneumococcal Carriage in Children under Five Years in Uganda-Will Present Pneumococcal Conjugate Vaccines Be Appropriate?
  15. 555
    “…Invasive pneumococcal disease and pneumococcal pneumonia cause substantial morbidity and mortality in the elderly. …”
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    Efficacy and Safety of the Pneumococcal Conjugate-13 Valent Vaccine in Adults
  16. 556
    “…CONCLUSIONS: If the patients in this sample had been previously vaccinated with PCV13 plus PPV23, theoretically, 50.8% of the cases of invasive pneumococcal disease that required hospital admission could potentially have been prevented. …”
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    Theoretical pneumococcal vaccine coverage: analysis of serotypes isolated from inpatients at a tertiary care hospital
  17. 557
    “…Geographic variations of invasive pneumococcal disease incidence and serotype distributions were observed after pneumococcal conjugate vaccine introduction at regional levels and among French administrative areas. …”
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    Association of Pneumococcal Conjugate Vaccine Coverage With Pneumococcal Meningitis: An Analysis of French Administrative Areas, 2001–2016
  18. 558
    “…Main outcome measures included incremental cost-effectiveness per quality-adjusted life year (QALY) gained and pneumococcal disease public health outcomes. RESULTS: Black cohorts had a greater risk of pneumococcal disease hospitalization compared to non-Black cohorts. …”
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    Cost-Effectiveness of Newly Recommended Pneumococcal Vaccination Strategies in Older Underserved Minority Adults in the USA
  19. 559
    “…It particularly affects those at the extremes of age and immunocompromised individuals. Preventing pneumococcal disease is paramount in at risk individuals, and pneumococcal vaccination should be offered. …”
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    Pneumococcal Vaccination in Immunocompromised Hosts: An Update
  20. 560
    “…Despite the dramatic decrease in invasive pneumococcal disease since the widespread use of the first pneumococcal vaccine, invasive and resistant disease still occurs. …”
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    Rare but not forgotten: A case of meningitis due to ceftriaxone-resistant Streptococcus pneumoniae
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