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761por Villar-Álvarez, Felipe, de la Rosa-Carrillo, David, Fariñas-Guerrero, Fernando, Jiménez-Ruiz, Carlos A.“…The new pneumococcal vaccines PCV15 and PCV20 will help to extend protection against pneumococcal disease in adults. The vaccine against COVID-19 is currently the most useful tool to prevent the disease and reduce its pathogenicity. …”
Publicado 2022
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762“…The impact of pneumococcal conjugate vaccines (PCVs) on invasive pneumococcal disease (IPD) burden has been extensively studied in children aged<5 years; however, a pooled estimation of the effect of PCVs on penicillin non-susceptible pneumococci (PNSP) has not yet been performed. …”
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763por Narciso, Ana Rita, Iovino, Federico, Thorsdottir, Sigrun, Mellroth, Peter, Codemo, Mario, Spoerry, Christian, Righetti, Francesco, Muschiol, Sandra, Normark, Staffan, Nannapaneni, Priyanka, Henriques-Normark, Birgitta“…Pneumococcal conjugate vaccines (PCVs) used in childhood vaccination programs have resulted in replacement of vaccine-type with nonvaccine-type pneumococci in carriage and invasive pneumococcal disease (IPD). A vaccine based on highly conserved and protective pneumococcal antigens is urgently needed. …”
Publicado 2022
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764por Desmet, Stefanie, Theeten, Heidi, Laenen, Lies, Cuypers, Lize, Maes, Piet, Bossuyt, Wouter, Van Heirstraeten, Liesbet, Peetermans, Willy E., Lagrou, Katrien“…After switching from 13-valent to 10-valent pneumococcal conjugate vaccine (PCV10) (2015–2016) for children in Belgium, we observed rapid reemergence of serotype 19A invasive pneumococcal disease (IPD). Whole-genome sequencing of 166 serotype 19A IPD isolates from children (n = 54) and older adults (n = 56) and carriage isolates from healthy children (n = 56) collected after the vaccine switch (2017–2018) showed 24 sequence types (STs). …”
Publicado 2022
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765por Neri, Margherita, Brassel, Simon, Schirrmacher, Hannah, Mendes, Diana, Vyse, Andrew, Steuten, Lotte, Hamson, Elizabeth“…This paper estimates the number of hospitalisations that current vaccines against influenza, pneumococcal disease (PD), COVID-19, and a hypothetical Respiratory Syncytial Virus (RSV) vaccine, could prevent in the winter among older adults in England. …”
Publicado 2023
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766“…Worldwide, conjugated pneumococcal vaccines (PCVs) have proven effective against invasive pneumococcal disease, but non-invasive pneumonia is a major cause of mortality in young children and serotypes vary geographically, affecting effectiveness. …”
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767“…CONCLUSION: We recommend, based on the model predictions, that strategies to control pneumococcal disease and organism transmission should include reducing the group size in day-care centers.…”
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768por Rhodes, Julia, Hyder, Joseph A., Peruski, Leonard F., Fisher, Cindy, Jorakate, Possawat, Kaewpan, Anek, Dejsirilert, Surang, Thamthitiwat, Somsak, Olsen, Sonja J., Dowell, Scott F., Chantra, Somrak, Tanwisaid, Kittisak, Maloney, Susan A., Baggett, Henry C.“…Our findings highlight the limitations of culture-based detection methods to estimate invasive pneumococcal disease incidence in settings where pre-culture antibiotic use is common.…”
Publicado 2010
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769por Moore, Catrin E., Sengduangphachanh, Amphone, Thaojaikong, Thaksinaporn, Sirisouk, Joy, Foster, Dona, Phetsouvanh, Rattanaphone, McGee, Lesley, Crook, Derrick W., Newton, Paul N., Peacock, Sharon J.“…A prospective hospital-based study was undertaken to define the incidence of invasive pneumococcal disease (IPD) and circulating serotypes in Laos. …”
Publicado 2010
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770por Daigneault, Marc, De Silva, Thushan I., Bewley, Martin A., Preston, Julie A., Marriott, Helen M., Mitchell, Andrea M., Mitchell, Timothy J., Read, Robert C., Whyte, Moira K. B., Dockrell, David H.“…These changes were associated with enhanced bacterial clearance in the lung and reduced levels of invasive pneumococcal disease.…”
Publicado 2012
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771“…The 7 and 13-valent pneumococcal conjugate vaccines are mostly used in routine infant immunizations to prevent the development of pneumococcal disease. Currently, the dosing schedule approved and recommended for PCV7 and PCV13 in infants is 3 primary doses followed by a booster dose in the second year of life. …”
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772por Rosch, Jason W, Iverson, Amy R, Humann, Jessica, Mann, Beth, Gao, Geli, Vogel, Peter, Mina, Michael, Murrah, Kyle A, Perez, Antonia C, Edward Swords, W, Tuomanen, Elaine I, McCullers, Jonathan A“…A live vaccine candidate based on deletion of the signal recognition pathway component ftsY induced potent, serotype-independent protection against otitis media, sinusitis, pneumonia and invasive pneumococcal disease. Protection was maintained in animals coinfected with influenza virus, but was lost if mice were depleted of CD4(+) T cells at the time of vaccination. …”
Publicado 2014
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773por Safari, Dodi, Kurniati, Nia, Waslia, Lia, Khoeri, Miftahuddin Majid, Putri, Tiara, Bogaert, Debby, Trzciński, Krzysztof“…These findings may facilitate potential preventive strategies that target invasive pneumococcal disease in Indonesia.…”
Publicado 2014
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774por Mahdi, Layla K., Van der Hoek, Mark B., Ebrahimie, Esmaeil, Paton, James C., Ogunniyi, Abiodun D.“…This work extends our previous analyses and suggests that both PrtA and SodA warrant examination in future studies aimed at prevention and/or control of pneumococcal disease.…”
Publicado 2015
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775Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Childrenpor Lundbo, Lene F., Harboe, Zitta Barrella, Clausen, Louise N., Hollegaard, Mads V., Sørensen, Henrik T., Hougaard, David M., Konradsen, Helle B., Nørgaard, Mette, Benfield, Thomas“…We aimed to replicate previous findings of genetic variation associated with invasive pneumococcal disease (IPD), and to assess whether similar associations could be found in invasive meningococcal disease (IMD). …”
Publicado 2015
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776“…PURPOSE: Pneumococcal disease leads to renal complications ranging from persistent proteinuria to end-stage renal disease. …”
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777por Wilson, Robert, Cohen, Jonathan M., Reglinski, Mark, Jose, Ricardo J., Chan, Win Yan, Marshall, Helina, de Vogel, Corné, Gordon, Stephen, Goldblatt, David, Petersen, Fernanda C., Baxendale, Helen, Brown, Jeremy S.“…Naturally acquired immunity against invasive pneumococcal disease (IPD) is thought to be dependent on anti-capsular antibody. …”
Publicado 2017
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778por Mahdi, Layla K., Higgins, Melanie A., Day, Christopher J., Tiralongo, Joe, Hartley-Tassell, Lauren E., Jennings, Michael P., Gordon, David L., Paton, Adrienne W., Paton, James C., Ogunniyi, Abiodun D.“…We propose that SpGlpO is a promising vaccine candidate against pneumococcal carriage, and warrants inclusion in a multi-component protein vaccine formulation that can provide robust, serotype-independent protection against all forms of pneumococcal disease.…”
Publicado 2017
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779por Chochua, Sopio, Metcalf, Benjamin J., Li, Zhongya, Walker, Hollis, Tran, Theresa, McGee, Lesley, Beall, Bernard“…We used whole-genome sequencing to characterize 199 nonvaccine serotype 35B pneumococcal strains that caused invasive pneumococcal disease (IPD) in the United States during 2015–2016 and related these findings to previous serotype 35B IPD data obtained by Active Bacterial Core surveillance. …”
Publicado 2017
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780por Chalmers, James, Campling, James, Ellsbury, Gillian, Hawkey, Peter M., Madhava, Harish, Slack, Mary“…Pneumococcal disease has a high burden in adults in the United Kingdom (UK); however, the total burden is underestimated, principally because most cases of community-acquired pneumonia (CAP) are non-invasive. …”
Publicado 2017
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